Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Alternative Models for Alcohol-Related Research
Our speakers in this session will challenge convention by using novel methods and approaches in alcohol research.
3:45 pm - 4:10 pm
"Using Zebrafish to Model Gene-Ethanol Interactions and Their Impact on Craniofacial Development"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"CTGF Regulation During Liver Regeneration: Involving Yap Activity that Is Antagonized by HNF4a and Required for Ethanol-Detoxification"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Pathophysiology of Alcohol-Related Organ Damage
Mechanisms of disease progression in multiple organs will be discussed in this session related to alcohol-induced end organ damage.
7:30 pm - 7:50 pm
"Impact of Chronic Alcohol Consumption on Mitochondrial Physiology in Aging Rats"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Impact of Chronic Alcohol and Hepatocyte Circadian Clock Disruption on Diurnal Rhythms of Lipid Droplet-Associated Genes and Hepatic Steatosis"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Role of P62 in Chronic-Plus-Binge Alcohol-Induced Hepatic Protein Aggregates and Stress Granules"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Hepatic Ceramide Reduction Alleviates Alcoholic Steatosis and Insulin Resistance in Female Mice"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Adipocyte Death Contributes to Alcoholic Liver Injury"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Translational/Therapeutic Developments in Alcohol-Induced Tissue Injury
This session will connect "bench to bedside" concepts in alcohol-related diseases.
9:00 am - 9:25 am
"Translational Studies in Alcoholic Hepatitis"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"miRNA Regulation of PBMCs in Alcoholic Hepatitis"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Immunohistochemistry Analyses of Inflammatory Cells and Signaling Pathways in Severe Alcoholic Hepatitis"
10:25 am - 10:30 am
Discussion
10:30 am - 10:55 am
"Critical Role of TFEB-Mediated Lysosomal Biogenesis in Alcohol-Induced Pancreatitis in Mice and Humans"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: What Can You Learn from Successful Scientists?
This session will adopt a "speed mentoring" format with Drs Arteel, Bailey, Pritchard and Li, allowing trainees to interactively discuss a wide range of topics related to mentor/mentee relationships (communication), self-motivation, overcoming scientific hurdles/funding issues, funding mechanisms for trainees, work-life balance and mental health.
1:30 pm - 2:30 pm
Panel Discussion
Interactive Focus Groups
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes