Multimodal Approaches to Mechanisms and Therapeutic Targets

This inaugural, 2025 Gordon Research Conference on Alzheimer’s Disease will bring together scientists from academia and industry to discuss the latest breakthroughs in the study of neurodegeneration[YJ1] in Alzheimer’s disease and related dementias. The conference will focus on complementary approaches to study genetic etiology, molecular and cellular mechanisms of disease, biomarkers and endophenotypes associated with disease progression, and potential therapeutic opportunities. The scientific sessions will focus on recent technological innovations for studying these questions, covering recent discoveries spanning functional genomics, epigenetics, systems biology, multi-omics, neuroimaging, and including clinical heterogeneity and machine learning integration of diverse datasets. A major goal of this conference is to bring leading neuroscientists from both northern and southern hemispheres to communicate exciting science and to foster new collaborations through formal scientific sessions as well as during informal interactions. To promote the next generation of neuroscientists, short talks will be specifically selected from abstracts submitted by students, postdoctoral fellows, and early career faculty members. This inaugural Alzheimer’s disease GRC will also serve as a forum for trainees to broaden their peer network, bringing together scientists from around the world to discuss and identify new directions in the field of neurodegeneration.