Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Dissecting Amygdala Function Across Translational Scales
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
"The Human Amygdala, Threat and Anxiety: Translational Progress and Challenges"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
"Solving the Valence Assignment Problem"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Dissociable Contributions of the Amygdala and Ventral Hippocampus to Stress-Induced Changes in Defensive Behavior"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Intersection of Stress and Social Function in the Amygdala"
9:55 am - 10:05 am
Discussion
10:05 am - 10:25 am
"Opposing Amygdala-Striatal Pathways Allow Stress to Promote Habits"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:30 am
"Dynorphin / Kappa-Opioid Receptor Regulation of Excitation-Inhibition Balance Toggles Afferent Control of Prefrontal Cortical Circuits in a Pathway-Specific Manner"
11:30 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Human Threat Circuitry in the Aftermath Trauma"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Neural Circuits Underlying Estrous Cycle Regulation of State-Dependent Emotional Memory"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Sex Differences in the Amygdala
6:00 pm - 6:20 pm
"Adolescent Stress Reprograms Sex Differences in the Medial Amygdala Transcriptome and Reward"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Sex Differences in Neural Projections of Fear Processing in Mice and Humans"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Brain Sex is a State Defined by Gonadal Hormones"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Sex Differences in the Human Extended Amygdala"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Value, Decision Making and the Amygdala
9:00 am - 9:20 am
"Amygdala Inputs to Striatum Regulate Exploratory Decision Making"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Causal Constraints on Value Estimation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Prefrontal-Amygdala Circuit Maturation and its Role in Adaptive Threat Avoidance"
10:20 am - 10:30 am
Discussion
10:30 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Neural Substrates of Approach-Avoidance Conflict"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
"Distributed Coding in Auditory Thalamus and Amygdala During Aversive Learning"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Molecular and Neural Mechanism of Behavioural Integration in the Extended Amygdala"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Microcircuitry and Modulation in the Amygdala
6:00 pm - 6:20 pm
"Aversive Memory and Learning Rule Update by the Parabrachial-to-Amygdala Network"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Reorganization of Memory Cell Ensembles by Re-Learning"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Novel Amygdala Mechanisms Orchestrating Fear"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Contribution of the Insular Cortex to Anxiety: Dissection in Pre-Clinical Models of Healthy and Pathological States"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Aversive Learning and the Amygdala
9:00 am - 9:20 am
"The Reorganization of Short and Long-Range Medial Prefrontal Projections in Consolidation of Threat Memories"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cortico-Amygdala Regulation of Fear Propagation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:35 am
Coffee Break
10:35 am - 10:55 am
"Dynamic Encoding of Internal States in Amygdala Circuit"
10:55 am - 11:05 am
Discussion
11:05 am - 11:25 am
"Ovarian Hormones Tune Amygdala Inhibition to Drive Anxiety-Like Behavior Across the Reproductive Cycle"
11:25 am - 11:35 am
Discussion
11:35 am - 11:50 am
"Ovarian Hormones Tune Amygdala Inhibition to Drive Anxiety-Like Behavior Across the Reproductive Cycle"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Encoding the Interactions between Appetitive and Aversive Signals in the Central Amygdala"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Appetitive Learning and the Amygdala
6:00 pm - 6:20 pm
"Neuromodulation of valence encoding amygdala ensembles"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Cell Type-Specific and Spatially-Resolved Molecular Signatures of PTSD across Cortico-Amygdala Circuits in the Human Brain"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"An Amygdala-Cortical Circuitry Controls the Striatal Memory System Driving Stimulus-Based Decisions"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"The Role of Dopamine D2 Receptors in the Basolateral Amygdala in Punishment-Based Risky Decision Making"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Amygdala Regulation of Pain and Arousal
9:00 am - 9:20 am
"The Posterior Capsular Subnucleus of the Central Amygdala (pCeC) - A Nociceptive Site Receiving Direct Inputs from Pain-Activated Parabrachial Neurons"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Sex-Dependent Effects of Adolescent Alcohol on Central Amygdala and Nociception"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Functional and Genetic Dissection of a Nociceptive Amygdala to Accumbens Neural Circuit"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Amygdalar Involvement in Gut Microbiome-Related Pain Signaling"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Reverse-Engineering Physiological Arousal and Anxiety within Extended Amygdala Circuits"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Modulation of Injury-Induced Hypersensitivity by Central Amygdala-Projecting Parabrachial Neurons"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:20 pm
"Amygdala Circuit Control of Social Behavior in Typical and Perturbed Development"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Maturation of the Prefrontal-Amygdala Pathway and Developmental Regulation of Emotional Learning"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Early Experiences and the Developing Human Amygdala"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Functional Development of the Primate Amygdala and Early Life Pathological Anxiety"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure