| Sunday August 15 PM (7:00 - 9:30) | Vasculogenesis and Angiogenesis |
Sunday afternoon: arrival, registration, dinner (6:00 p.m.)
Chair: Patricia A. D'Amore, Schepens Eye Research Institute/Harvard Medical School
- Patricia A. D'Amore, Welcome & Introductions
- Peter Carmeliet, Center for Transgene Technology & Gene Therapy
"Molecular Analysis of Vascular Development: Role of VEGF, Hypoxia and VE-Cadherin"
Coffee Break
- George Yancopoulos, Regeneron Pharmaceuticals, Inc.
"Emerging Roles of the Angiopoietins in Normal and Abnormal Angiogenesis"
- Charlie Little, Medical University of South Carolina
"De Novo Formation of Blood Vessels"
| Monday August 16 AM (9:00 - 12:30) | Development and Remodeling |
Chair: Andras Nagy, Samuel Lunenfeld Research Institute
- Kari Alitalo, University of Helsinki
"VEGFs and Receptors Involved in Angiogenesis and Lymphangiogenesis"
- Shahin Rafii, Cornell University
"Reconstitution of Angiogenesis by Transplantation and Engraftment of Ex Vivo Expanded Human AC133+CD34+KDR+ Endothelial Progenitor Cells"
Coffee Break
- Eli Keshet, The Hebrew University Hadassah Medical School
"Vascular Pruning"
- David Anderson, Howard Hughes Medical Institute
"Angiogenesis and the Problem of Vessel Identity"
| Monday August 16 PM (7:00 - 9:30) | Pericytes: Differentiation and Function |
Chair: Elisabetta Dejana, Mario Negri Institute
- Christer Betsholtz, University of Gothenburg
"Recruitment of Vascular Smooth Muscle Cells and Pericytes in Embryonic and Tumor Angiogenesis"
- Ira Herman, Tufts University
"Signaling Pathways Controlling Pericyte Growth and Differentiation"
Coffee Break
- Laura Benjamin, The Hebrew University Hadassah Medical School
"The Role of Pericytes in Angiogenesis and Remodeling in the Developing Retina" (15 min)
- Short presentation, selected from Poster Session
| Tuesday August 17 AM (9:00 - 12:30) | Cell-Cell Interactions |
Chair: David Shepro, Boston University
- Elisabetta Dejana, Mario Negri Institute
"The Role of VE-Cadherin in Angiogenesis"
- Brian Duling, UVA Health Sciences Center
"Gap Junctional Communication in the Microcirculation"
Coffee Break
- Diane Darland, Schepens Eye Research Institute
"Heterotypic Cell-Cell Interactions in a Three-Dimensional Culture System" (15 min)
- William Aird, Beth Israel Deaconess Medical Center
"Vascular Bed-Specific Gene Regulation"
| Tuesday August 17 PM (7:00 - 9:30) | Angiogenesis in Reproduction |
Chair: Peter Rogers, Monash Medical Centre
- Hellmut Augustin (Ovary), University of Gottingen Medical School
"Life Cycle of the Ovarian Vasculature: Angiogenesis, Vessel Maturation, and Vessel Regression
- Napoleone Ferrara (Ovary), Genentech
"VEGF, An Essential Regulator of Reproductive Angiogenesis"
Coffee Break
- Susan Fisher (Placenta), UCSF
"Human Placental Cytotrophoblasts: Masters of Vascular Morphing"
- Short presentation, selected from Poster Session
| Wednesday August 18 AM (9:00 - 12:30) | Regulating Angiogenesis |
Chair: Luisa Ireula-Arispe, UCLA
- Urban Deutsch, Kerckhoff Institute
"Regulation of Vascular Remodeling by Receptor Tyrosine Kinases"
- Dave Cheresh, The Scripps Research Institute
"Integrins in Angiogenesis"
Coffee Break
- Jan Kitajewski, Columbia University
"Notch Function in Vascular Development"
- Celeste Simon, University of Chicago
"Role of bHLH-PAS Proteins in Angiogenesis"
| Wednesday August 18 PM (7:00 - 9:30) | Novel Molecules in the Control of Vessel Formation and Function |
Chair: Ramzi Cotran, Brigham & Women's Hospital
- William Kaelin, Howard Hughes Medical Institute
"Inhibition of Angiogenesis by the Von Hippel-Lindau Tumor Suppressor Protein"
- Mike Klagsbrun, Harvard Medical School
"VEGF-Neuropilin Interactions"
Coffee Break
- Anne Marie Schmidt, Columbia University
"Receptor for AGE (RAGE): Implications for Vascular and Inflammatory Dysfunction in Diabetes and Other Disorders"
- Short presentation, selected from Poster Session
| Thursday August 19th AM (9:00 - 12:30) | Tumor Angiogenesis |
Chair: Shmuel (Muli) Ben-Sasson, The Hebrew University Hadassah Medical School
- Rakesh Jain, Massachusetts General Hospital
"Tumor Angiogenesis and Microcirculation: New Insights"
- Donald McDonald, UCSF
"Phenotypic Changes in Endothelial Cells at Sites of Angiogenesis in Chronic Inflammation and Tumors"
Coffee Break
- Doug Hanahan, UCSF
"Matrix Metalloproteinases: Components of the Angiogenic Switch During Tumorigenesis"
- Hal Dvorak, Beth Israel Deaconess Medical Center
"The Angiogenic Response Induced by VPF/VEGF"
| Thursday August 19th PM (7:00 - 9:30) | Therapeutics: Pro- and Anti-Angiogenesis |
Chair & Discussant: Harold Dvorak, Beth Israel Hospital
- Jeff Isner, Tufts University
"Cytokines and Cell Therapeutics for Myocardial and Limb Ischemia"
- Renata Pasqualini, The Burnham Institute
"Vascular Targeting In Vivo"
Coffee Break
- Judah Folkman, Children's Hospital
"Control of Tissue Mass by Vascular Endothelium"
- Short presentation, selected from Poster Session
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