Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: New Frontiers in Angiogenesis and Endothelial Cell Physiology
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:10 pm
"Exploring Muscle Development, Disease and Regeneration"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Reprogramming the Tumor Microenvironment to Enhance Cancer Treatment: Bench to Bedside"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Signaling Pathways and Networks
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Overcoming TEKnical Challenges on the Road to New Vascular Therapies"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
"The Tyrosine Kinase Receptor Tie1 Shapes Different Organo-Specific Wnt Codes"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Organotypic Regulation of the Vascular Barrier"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Designer Adaptable Endothelium to Decipher Vascular Heterogeneity"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"CDS2 Deficiency Converts Outcome of VEGFa Signaling from Angiogenesis to Vascular Regression"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Eavesdropping Cardiovascular Regulation at Single Cell Level"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Developmental Fate, Plasticity and Differentiation
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Angiocrine Signals and Epithelial Mesenchymal Transition"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Coronary Revascularization After Injury Is Regulated by Endocardial and Epicardial Cues and Forms a Scaffold for Cardiomyocyte Regeneration"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Novel Mechanisms Regulating Early Vascular Development"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
"Was Controls Cell Migration During Vascular Remodeling"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Investigating the Embryonic Origins of Endothelial Heterogeneity"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Vascular Control of Organ Function
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Mechanisms of Vascular Specialization in Lymph Node and Intestine"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Hepatic Angiodiversity: Vascular Control of Liver Function and Disease"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Molecular Determinants of Intrahepatic Vascular Zonation"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Guidance of Vascular Barrier Formation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Activating NO-sGC Pathway in Pericytes Ameliorates Inflammation-Induced Lung Injury"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Vascular Control of Oligodendrocyte Precursor Specification"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Angiocrine Metabolic Signaling Controls Muscle Regeneration by Instructing Macrophage Functional Polarization"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Remodeling of the Aging Vasculature
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Cellular Heterogeneity and Plasticity in Vascular Growth"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Vascular Cell Heterogeneity and Disease"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Role of Circadian Clock Gene in Retinal Vascular Remodeling"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Building Resilience in the Vascular Wall"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Differentiation and Functions of Organotypic Vasculatures
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"The Heterogenous Origin of Endothelial Cells in Blood and Lymphatic Vasculature"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Kidney Organoids as a Dual Model of Vascular Regression and Angiocrine Signaling"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Endothelial Cells in Adipose Tissue"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"How Chromatin-Remodeling Enzymes Reveal Insights into Organ-Specific Vascular Development and Maintenance"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"DNA Methylation of a Non-Coding RNA Cluster and Endothelial Cell Fates"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Mechanically Induced Angiocrine Signals"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Novel Technological Developments to Study Vascular Morphogenesis
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Genetic Targeting of Organ Specific Vessels"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:15 pm
"EXC-4/CLIC Proteins Are Ancient Regulators of Rho-Family GTPase Signaling in Tubulogenesis and Angiogenesis"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Using Multispectral Genetic Mosaics to Enlighten Vascular Cell Heterogeneity"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Regulatory Pathways Governing Coronary Vessel Development Are Dysregulated After Myocardial Infarction in the Adult Heart"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Transcriptional Basis of How S1P Regulates Primary Vascular Network Formation"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Systems Biology Approaches Towards Angiogenesis and Vascular Differentiation
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Angiogenesis Revisited: The Role and (Therapeutic) Implications of Endothelial Metabolism"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Control of Endothelial Quiescence by FOXO Regulated Metabolites"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"N-Glycome Regulation Limits the Endothelial Transition to Hematopoietic Stem Cells"
10:15 am - 10:25 am
Discussion
10:25 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"TGFβ Signaling in Vascular Development"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Transcription Networks Regulating Endothelial Lineage and Function"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Low PI3-Kinase Signaling Permits Pericyte Maturation During Angiogenesis"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Hemodynamic Regulation of Valve Development and Function"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Angiogenesis in Disease and Vascular Targeted Therapies
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Organotypic Angiocrine Signatures in Aging Tissue Compartments"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Anti-Angiogenic Immunotherapy"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Temporal Multi-Omics Identifies LRG1 as Vascular Niche Instructor of Early Metastatic Colonization"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"New Insights into the Functional Role of Organ Specific Vasculature and Cell Specific Tumor Stroma in Cancer Progression and Metastasis"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure