Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Endothelial Cell Specification and Differentiation
Discussion Leader: Anne Karine Lagendijk (University of Queensland, Australia)
3:45 pm - 4:05 pm
Didier Stainier (Max Planck Institute for Heart and Lung Research, Germany)
"Endothelial Cell Development in Zebrafish"
4:05 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Alice Neal (University of Oxford, United Kingdom)
"Vein Identity Requires BMP Signalling"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Angiogenesis, Metabolism and Disease / Keynote Session: Vascular Patterning
Discussion Leaders: David Kallenberg (University College London, United Kingdom) and Emma Gordon (Uppsala University, Sweden)
7:30 pm - 7:40 pm
Robert Johnson (University of East Anglia, United Kingdom)
"Regulating Post-Natal Retinal Angiogenesis: A Fresh Look at the Roles of avβ3 and a5β1 Integrins"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Joanna Kalucka ( Vesalius Research Centre (VRC), VIB-KU Leuven, Belgium)
"Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Masataka Yokoyama (Weill Cornell Medicine, USA)
"Endothelial p53 Prevents the Aging Stress-Induced Adipose Tissue Malignancy"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Alexandre Dubrac (Yale University, USA)
"Inhibiting Nck-Dependent Pericyte Migration Improves Pathological Neoangiogenesis During Retinopathy"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Heike Stingl (Institute for Vascular Signalling, Goethe University Frankfurt, Germany)
"The Role of AMP-Activated Protein Kinase a1 in Angiogenesis"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Marc Schwab (University of Zurich, Switzerland)
"Nogo-A and S1PR2 as Novel Regulators of Developmental and Tumor Angiogenesis in the CNS"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Anne Eichmann (Yale School of Medicine, USA)
"Vascular Patterning in Development and Disease"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Novel Methods to Study Angiogenesis / Vascular Integrity and Permeability
Discussion Leaders: Michael Potente (Max Planck Institute for Heart and Lung Research, Germany) and Georgia Zarkada (Yale University, USA)
9:00 am - 9:10 am
Akanksha Bhargava (Johns Hopkins University, USA)
"High-Fidelity Image-Based Modeling of Structural and Functional Angiogenic Heterogeneity in Breast Cancer"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
H.H. Greco Song (Massachusetts Institute of Technology, USA)
"Synthetic Functional Vasculature as an Organ-on-a-Chip Platform"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Serena Zacchigna (International Center for Genetic Engineering and Biotechnology / University of Trieste, Italy)
"Understanding the Poor Angiogenic Capacity of the Mammalian Heart"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
David Gurevich (University of Bristol, United Kingdom)
"Live Imaging of Wound Angiogenesis Reveals How Phenotypic State of Macrophages Directs Vessel Sprouting and Subsequent Vessel Resolution"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Bongnam Jung (Uppsala University, Sweden)
"The Role of FGFBP1 in the Central Nervous System"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Sinem Karaman (Wihuri Research Institute / University of Helsinki, Finland)
"Interplay of VEGFRs in the Regulation of Vascular Permeability"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Ross Smith (Uppsala University, Sweden)
"Vascular Permeability via VEGF/VEGFR2 Contributes to Pathological Angiogenesis in the Eye"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Nicolas Ricard (Yale Cardiovascular Research Center, USA)
"ERK1/2 Pathway Is Critical for Maintenance of Vascular Integrity"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Anne Eichmann (Yale School of Medicine, USA)
1:30 pm - 2:30 pm
Panel Discussion
Career Development
Roberto Buccione (EMBO Molecular Medicine, EMBO Press, Germany)
Michael Potente (Max Planck Institute for Heart and Lung Research, Germany)
Didier Stainier (Max Planck Institute for Heart and Lung Research, Germany)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes