Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Endothelial Cell Homeostasis and Regeneration
Discussion Leader: Haley Barlow (University of Texas Southwestern Medical Center, USA)
3:45 pm - 4:05 pm
Luisa Iruela-Arispe (University of California, Los Angeles, USA)
"Endothelial Repair in Large Arteries"
4:05 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Nathalie Tisch (Heidelberg University, Germany)
"Caspase-8 Is a Prosurvival Factor in Endothelial Cells of the Gut-Vascular Barrier"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Signaling and Endothelial Cell Function
Discussion Leaders: Dominic Love (Uppsala University, Sweden) and Raphael Lis (Weill Cornell Medicine, USA)
7:30 pm - 7:40 pm
Saptarshi Biswas (Columbia University Irving Medical Center, USA)
"Wnt/Beta-Catenin Inhibitor Apcdd1 Regulates Blood-Retinal Barrier Maturation by Modulating Neurovascular Unit Integrity"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Linda Lorenz (Institute of Metabolic Physiology, Heinrich Heine University Düsseldorf, Germany)
"Identification of Angiocrine Signals to Promote Liver Growth and Survival"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Robert Johnson (University of East Anglia, United Kingdom)
"Endothelial Fibronectin Receptors: avβ3-Integrin, a5β1-Integrin and Neuropilin-1 Regulate VEGFR2 and Hippo-YAP/TAZ Dependent Angiogenesis"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Yu Ting Ong (Max Planck Institute for Heart and Lung Research, Germany)
"A YAP/TAZ-TEAD Signaling Module Controls Endothelial mTORC1"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Ashraf Ul Kabir (Washington University School of Medicine in St. Louis, USA)
"Myct1 Is a Novel Regulator of Tumor Angiogenesis"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Laura Pisarsky (Fred Hutchinson Cancer Research Center, USA)
"Disruption of Vascular Homeostasis Awakens Dormant Disseminated Tumor Cells"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Christian Helker (Philipps-Universität Marburg, Germany)
"Apelin Signaling Switches Quiescent Vascular Endothelial Cells into a Pro-Angiogenic State"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Kerstin Wilhelm-Jüngling (Max Planck Institute for Heart and Lung Research, Germany)
"Control of Lymphatic Vessel Size by FOXO Transcription Factors"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Keynote Session: Single Cell Transcriptomics / New Technologies and Approaches in Vascular Biology
Discussion Leaders: Katelyn Cabral (University of California, San Francisco, USA) and Brisa Palikuqi (Weill Cornell Graduate School of Medical Sciences, USA)
9:00 am - 9:20 am
Christer Betsholtz (Uppsala University, Sweden)
"A Single-Cell Perspective on Vascular Biology"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Yifan Yuan (Yale University, USA)
"Purified Pulmonary Microvascular Endothelial Cells for Pulmonary Microvascular Engineering as Evaluated by Single-Cell Transcriptomics"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Sinem Karaman (Wihuri Research Institute / University of Helsinki, Finland)
"Organotypic Sensitivity of Vessels to Loss of Vascular Endothelial Growth Factor Signaling"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Tyler Lu (Weill Cornell Medicine, USA)
"Human Induced Pluripotent Stem Cell-Derived Neuroectodermal Epithelial Cells Mistaken for Blood-Brain Barrier-Forming Endothelial Cells"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Mark Richards (Uppsala University, Sweden)
"Claudin5 Expression in Dermal Venules Restricts Macromolecular Leakage to VEGF-A but Not Histamine"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Heon-Woo Lee (Yale University, USA)
"Generation of Venous-Endothelial Cell Specific Inducible Cre Mice Using BAC Cloning"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Kazuhide Okuda (University of Queensland, Australia)
"Real Time Visualization of Endothelial Erk Signalling During Angiogenesis and Vessel Remodelling in Zebrafish"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Meet the Editors
Does the editorial process seem puzzling? This session will provide an opportunity to hear and discuss about high impact scientific journals, including publishing, being an author or reviewer, developing track records, and pursuing a career in scientific publishing.
Discussion Leader: Lowell Edgar (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom)
1:30 pm - 1:40 pm
Priscilla Kelly (Science, AAAS, USA)
"Publishing in High Impact Journals"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
Wei Wong (Science Signaling, AAAS, USA)
"Lab to Editor"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:30 pm
Panel Discussion
Scientific Publishing and Career Development for Vascular Biologists
Priscilla Kelly (Science, AAAS, USA)
Wei Wong (Science Signaling, AAAS, USA)
Christer Betsholtz (Uppsala University, Sweden)
Luisa Iruela-Arispe (University of California, Los Angeles, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
