Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Endothelial Cell Development and Diversity
Discussion Leader: Jesus Gomez Salinero (Weill Cornell Medicine, United States)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
Rui Benedito (Centro Nacional de Investigaciones Cardiovasculares (CNIC), Spain)
"Unraveling Angiogenesis and CV Disease with Single Cell Genetics"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Modelling Vascular Organotypicity
Discussion Leaders: Brisa Palikuqi (UCSF, United States) and Tyler Lu (Weill Cornell Medicine, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:45 pm
Greg Farber (UNC Chapel Hill, United States)
"Direct Highly Efficient Endothelial Reprogramming Using Sox17-Erg"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
Taylor Chavez (Duke University, United States)
"Vascular Engineering to Study Sexual Dimorphisms During Development"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:15 pm
Laura Gutierrez Miranda (Weizmann Institute of Science (WIS), Israel)
"Unraveling Novel Players of Zebrafish Marrow Vasculature Formation"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Bong-Ihn Koh (Max Planck Institute for Molecular Biomedicine, Germany)
"Sustained Vascular Growth in Aging-Resistant Skull Bone Marrow Expansion"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Kevin Chen (Weill Cornell Medicine, United States)
"Exploring the Role of ATOH8 in Pancreatic Endothelial Cells: Implications for Health and Disease."
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
Eunhyeong Lee (Columbia University Irving Medical Center, United States)
"Angiopoietin-2 Blockade Reduces Growth of Liver Metastases From Pancreatic Neuroendocrine Tumors by Enhancing Vascular Integrity and T-cell Infiltration"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Mechanisms of Vascular Development and Maintenance
Discussion Leader: Ivan Xia (Yale University, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:15 am
Soo Jin Kim (Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, South Korea)
"Dynamic Pericyte Replacements Maintain Vascular Homeostasis"
9:15 am - 9:20 am
Discussion
9:20 am - 9:30 am
Sakurako Kobayashi (Peter MacCallum Cancer Centre, Australia)
"Don’t be so vein: Meox1 is a Context-Specific Target Gene that Regulates Venous Sprouting Downstream of Hippo Signalling"
9:30 am - 9:35 am
Discussion
9:35 am - 9:45 am
Chris Benwell (The Norwich Research Park, The Quadram Institute, United Kingdom)
"Endothelial Neuropilins Function as Master Regulators of a5Integrin Trafficking."
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
Jessica Furtado (Yale University, United States)
"Mechanisms of Blood Retinal Barrier Development"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
Dongying Chen (Yale Cardiovascular Research Center, United States)
"VEGF Counteracts Shear Stress-Determined Capillary-to-Artery Cell Fate Transition During Arteriogenesis"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Feston Idrizi (UMass Chan Medical School, United States)
"Integrated Single cell Molecular Analysis of Pericytes Reveals the cis-Regulatory Logic Governing their Identity"
10:30 am - 10:35 am
Discussion
10:35 am - 10:45 am
Fatemeh Mirzapour (Technical University of Munich, Germany)
"Vascular Branching Morphology and Tissue Perfusion: Therapeutic Implications"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: New Frontiers in Angioscience
Discussion Leader: Miki Kamiyama (Medical Faculty Mannheim, Heidelberg University, Germany)
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:05 pm
Stefania Nicoli (Yale University, United States)
"The Bottoms-up Problem Solving Approach: How to Investigate the Unknown"
2:05 pm - 2:15 pm
Discussion
2:15 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes