Sunday, April 20: 7:30 - 10:00 pm

Phylogenesis of the renin system

• H. Nishimura - Phylogeny of angiotensin receptors and signaling
• N. Hazon - RAS in elasmobranches
• M. Salzet - Renin and angiotensin converting enzyme in the Annelids
• E. Isaac - Insect angiotensin-converting enzyme: Comparative biochemistry and evolution

Monday, April 21: 9:30 am - 12:30 pm

G-protein coupling / Angiotensin coupling

• F. McKenzie - Vaso-active peptides and MAP kinases
• L. M. Luttrell - Regulation of tyrosine protein phosphorylation by G protein-coupled receptors
• B. Berk - Angiotensin II signal transduction: Role of tyrosine-kinase

Monday April 21: 4:30 - 7:30 pm

Angiotensin and CNS

• C. Llorens-Cortes - The role of aminopeptidase A in the metabolism of angiotensin in the brain
• M. Raizada - The AT₁ receptor and neuromodulation
• M. McKinley - Central angiotensinergic pathways involved in the neural and endocrine regulation of the kidneys

Tuesday, April 22: 9:30 am - 12:30 pm

Protein processing in health and diseases

• J. Arribas - A common mechanism governing the shedding of transmembrane proteins
• R. A. Black - TNFalpha converting enzyme: Proteolytic processing of a cell-surface protein by a mammalian adamalysin
• S. E. Gandy - Metabolism of the Alzheimer ß-amyloid precursor protein (ßAPB): Protein phosphorylation regulated ßAPP transport vesicle biogenesis in the TGN
• T. L. Reudelhuber - Intracellular targeting and proteolytic activation of human prorenin

Tuesday, April 22: 4:30 - 7:30 pm

Endothelin

• M. Yanagisawa - Endothelin: Vascular biology to genetics
• H. Kurihara - Gene targeting and overexpression of ET-1 in mice
• T. F. Luetscher - Endothelin receptor blockade from experimental models to patients with cardiovascular diseases

Wednesday, April 23: 9:30 am - 12:30 pm

Interactions of the renin-angiotensin system and the arginine/NO system

• G. Gibbons - Antagonistic roles of nitric oxide and angiotensin II in vascular remodeling and lesion formation: A matter of life and death
• E. Shesley - Altered blood pressures and renin concentration in mice lacking endothelial nitric oxide synthase
• T. Hintze - Interaction of angiotensin and bradykinin in the control of NO production and tissue oxygen consumption

Thursday, April 24: 9:330 am - 12:30 pm

Genetics

• J. Rapp - Rat hereditary hypertension: Towards gene identification
• J. Naggert - Experimental genetics in metabolic syndromes of the mouse
• J. Krege - Mutating genes to study hypertension
• L. Pascoe -Inherited disoders of steroid biosynthesis and hypertension caused by mutations in CYP11B genes

Thursday, April 24: 4:30 - 7:30 pm

Steroids and blood pressure regulation

• T. Balla - Novel elements of the inositide/calcium signaling pathway involved in AT₁ receptor-mediated cellular responses
• N. Cherradi - Mitochondrial sites of action of calcium in the acute regulation of mineralocorticoid biosynthesis by angiotensin II
• A. Agarwal - Mutations in 11ß-hydroxysteroid deshydrogenase (type II) gene as a cause of hypertension