| Sunday, 15th February |
- 2:00 pm - Registration
- 4:00 to 6:00 pm - Reception
- 6:00 pm - Dinner
|
| 7:00 - 10:00 pm: Transcriptional Regulation of RAS Genes |
Discussion Leader - Kathryn Sandberg - Georgetown University Medical Centre
- Curt Sigmund - University of Iowa
- Molecular mechanisms regulating the renin gene: role of cAMP and an upstream enhancer
- Ganes Sen - Cleveland Clinic Foundation
- Tissue-specific expression of angiotensin converting enzyme
- Kathleen Curnow - Baker Medical Research Institute, Australia
- Sequences determining the level of expression of AT1 genes
Discussants - Akiyoshi Fukamizu, Florence Pinet |
| Monday, 16th February |
- 8:30 am - Group Photograph
|
| 9:00 am - 12:30 pm: AT1 Receptors - Structure and Function |
Discussion Leader - Kevin J. Catt - Bethesda
- Dr. Stephen Ferguson - John P. Robarts Research Institute, Canada
- Molecular mechanisms of GPCR internalization
- Thomas Coffman - Duke University Medical Centre
- Insights into AT1 receptor function from gene targeting
- Anthony Balmforth - University of Leeds, UK
- Active conformation of the AT1 receptor
- Laszlo Hunyady - Semmelweis University, Hungary
- Structural basis of AT1 receptor regulation
Discussants - Jean-Claude Bonnafous, Sadashira Karnik, Walter Thomas |
- 4:30 - 6:00 pm - Poster Session
- 6:00 pm - Dinner
|
| 7:00 - 10:00 pm: Signalling of AT1 Receptors |
Discussion Leader - R. Wayne Alexander - Emory University School of Medicine
- R. Wayne Alexander - Emory University School of Medicine
- Role of Caveolae in angiotensin II signaling
- Eric Clauser - INSERM, France
- AT1 receptor mutants and signaling
- Kenneth Berstein - Emory University School of Medicine
- Angiotensin and JAK2 activation: a new paradigm in seven
transmembrane receptor coupling
Discussants - Bradford Berk, Tadashi Inagami, Jerry Nadler |
| Tuesday, 17th February |
| 9:00 am-12:30 pm: Genetics of Hypertension |
Discussion Leader - Stephen Harrap - University of Melbourne, Australia
- Howard Jacob - Medical College of Wisconsin
- Experimental genetic hypertension: selecting and separating phenotypes
- Nicholas Schork - Case Western Reserve University
- Weighing the genetic odds: what are the options?
- Guiseppi Bianchi - Universita Degli Studi di Milano, Italy
- Candidate genes, sodium and hypertension
Discussants - Eric Boerwinkle, Anna Dominiczak, Klaus Lindpaintner, Perrin White
- 4:00 - 6:00 pm - Poster Session
- 6:00 pm - Dinner
|
| 7:00 - 10:00 pm: Vascular Development - Differentiation & Remodelling |
Discussion Leader - Gary Owens - University of Virginia
- Richard Pratt - Harvard Medical School
- Role of AT2 receptors in vascular development
- Mike Mulvany - University Hospital in Åarhus, Denmar
- Vascular remodelling and angiotensin
- Gary Owens - University of Virginia
- Molecular regulation of SMC differentiation - potenial role for angiotensin II
Discussant - Marijke Brink, Yigal Pinto |
| Wednesday, 18th February |
| 9:00 am-12:30 pm - AT4 Receptors |
Discussion Leader - Joseph Harding - Washington State University
- Joseph Harding - Washington State University
- AT4 receptors: structural properties and heterogeniety
- John Wright - Washington State University
- Central actions mediated by AT4 receptors
- Siew-Yeen Chai - Howard Florey Institute, Australia
- Isolation of a neuropeptide with high affinity for the AT4 receptor: LVV-hemorphin-7
- Eric Pederson - Washington State University
- Cognitive-enhancing effects of central administration of LVV-hemorphin-7: reversal of scopolamine induces amnesia
- Douglas Vaughan - Vanderbilt University Medical Centre
- AT4 receptors and the regulation of endothelial cell gene expression
Discussants - Mohan Raizada, Conrad Sernia
- Afternoon - Free Time / Soccer Game
- 7:00 pm - Banquet
|
| Thursday, 19th February |
| 9:00 am -12:30 pm: Salt Sensitive Hypertension |
Discussion Leader - Gordon Williams - Brigham & Women's Hospital, Boston
- Bernard Rossier - Université de Lausanne, Switzerland
- The epithelial sodium channel and salt sensitive hypertension
- Steven Hunt - University of Utah
- Kallikrein, genes and salt-sensitive hypertension in humans
- J. Howard Pratt - Indiana University Medical Center
- Race, salt-sensitive hypertension and genes effecting sodium handling
Discussants - John Connell, Perin White
- 4:30 to 6:00 pm - Poster Session
- 6:00 pm - Dinner
|
| 7:00 - 10:00 pm: AT2 Receptor Function and Signalling |
Discussion Leader: - Thomas Unger - Klinikum des Christian-Albrechts Universität zu Kiel, Germany
- Robert Carey - University of Virginia
- AT2 mediated nitric oxide production in the kidney
- Masatsugu Horiuchi - Harvard Medical School
- Mechanisms of AT2 mediated apoptosis
- Colin Sumners - Univeristy of Florida
- PLA2/ arachidonic acid
- Clara Nahmias - CNRS-ICGM, France
- Role of SHP-1 tyrosine phosphatases in AT2 signaling
- Stephan Gallinat - Universität zu Kiel, Germany
- Role of the AT2 receptor in cell differentiation and tissue regeneration
Discussants - David Dudley |
| Friday, 20th February |
- Breakfast
- Conferees Depart
|
