SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | ANGIOTENSIN ANTAGONISM - FROM SNAKE VENOM TO VACCINE |
| Discussion Leader: Ernesto Schiffrin (McGill University) |
7:40 pm - 8:20 pm | Nancy Brown (Vanderbilt University School of Medicine)
"Historical, contemporary and emerging therapies" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Juerg Nussberger (Centre Hospitalier Universitaire Vaudois, Lausanne)
"Angiotensin vaccines in hypertension" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:05 am | A DECADE OF ACE2 - CLONING TO CLINIC |
| Discussion Leader: Anthony Turner (University of Leeds) |
9:00 am - 9:25 am | David Brenner (University of California, San Diego)
"ACE2 & Liver fibrosis and Inflammation" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:50 am | Hans Loibner (Apeiron, Vienna)
"Recombinant ACE2 in clinical trials" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break / Group Photo |
10:30 am - 10:55 am | Gavin Oudit (University of Alberta)
"ACE2 & Heart failure and Diabetes" |
10:55 am - 11:05 am | Discussion |
11:05 am - 12:30 pm | RECEPTOR SIGNALLING & DISEASES |
| Discussion Leader: László Hunyady (Semmelweis University) |
11:05 am - 11:30 am | Patrizia Nigro (University of Rochester)
"Cyclophilin A: a novel mediator of Angiotensin II pathophysiology" |
11:30 am - 11:40 am | Discussion |
11:40 am - 12:00 pm | Gervaise Loirand (INSERM, Université de Nantes)
"Angiotensin, Rho exchange factors & hypertension" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Marta Ruiz-Ortega (Universidad Autónoma Madrid, Madrid)
"Angiotensin II and TGF-beta: Role of AT1/Smad pathway in renal and vascular fibrosis" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GENETIC MODIFIERS & THE EXPRESSION OF COMPLEX PHENTOTYPES |
| Discussion Leader: Jose Eduardo Krieger (University of Sao Paulo Medical School) |
7:30 pm - 7:55 pm | Jonathan G. Seidman (Harvard Medical School)
"Genetic modifiers - genome wide mapping and validation" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | John Mullins (Queen's Medical Research Institute, Edinburgh)
"RAS genotypes in health and disease" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:55 pm | Ashok Kumar (New York Medical College)
"Human angiotensin receptor haplotype related to hypertension" |
8:55 pm - 9:05 pm | Discussion |
9:05 pm - 9:20 pm | Terry Elton (Ohio State University, Columbus)
"Combinatorial miRNA inhibition of the human angiotensin II type 1 receptor expression" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:05 am | ANGIOTENSIN & CELL PROGRAMMING |
| Discussion Leader: Dominik N. Müller (Max-Delbrück-Centrum) |
9:00 am - 9:25 am | Elias Zambidis (Johns Hopkins University School of Medicine)
"ACE/AT2R in Hematopoiesis" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:50 am | Thomas Walther (The University of Hull)
"Ang1-7 and hematopoietic progenitor cells" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:55 am | Aurelie Contrepas (INSERM, Collège de France)
"Prorenin Receptor & ES cell pluripotency" |
10:55 am - 11:05 am | Discussion |
11:05 am - 12:30 pm | YOUNG INVESTIGATOR SESSION |
| Early career scientists chosen from abstracts. |
| Discussion Leader: Kathryn Sandberg (Department of Medicine Georgetown University) |
11:05 am - 11:20 am | Nicola Clarke (University of Leeds, UK) |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Jose Lopes (Instituto de Farmacologia & Terpeutica, Portugal) |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:50 am | Young-Soo Song (Duke University Medical Center, Durham) |
11:50 am - 12:05 pm | Discussion |
12:05 pm - 12:20 pm | Hamiyet Unal (Lerner Research Institute, Cleveland) |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | STRETCH & ANTIBODY MEDIATED ACTIVATION OF AT1 RECEPTORS |
| Discussion Leader: Sadashiva Karnik (Cleveland Clinic Foundation) |
7:30 pm - 7:55 pm | Issei Komuro (Chiba University Graduate School of Medicine)
"Molecular & Therapeutic implications of stretch-sensing by the AT1R" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Thomas Gudermann (Ludwig-Maximilians-Universitaet)
"AT1R as Mechanosensors" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Yang Xia (University of Texas Medical School, Houston)
"AT1R Autoantibodies in preeclampsia" |
9:05 pm - 9:15 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | DIABETIC COMPLICATIONS & THE RAS |
| Discussion Leader: Mark Cooper (Baker IDI Heart and Diabetes Research Institute) |
9:00 am - 9:30 am | Rudy Bilous (Newcastle University)
"Microvascular Complications" |
9:30 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Jennifer Wilkinson-Berka (Monash University, Melbourne)
"Aliskerin improves diabetic and ischemic retinopathy in transgenic ren-2 rats" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 11:00 am | Janos Peti-Peterdi (University of Southern California)
"Glucose & Renin" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:40 am | Atsuhiro Ichihara (Keio University School of Medicine)
"Pro-renin Receptor Antagonism" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Ravi Nistalla (University of Missouri-Columbia School of Medicine)
"Ang II, oxidative stress and proteinuria: Is megalin the missing link?" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Eric Lazartigues (Louisiana State University Health Sciences Center)
"ACE2 and the pancreas" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session III |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | OPPORTUNITIES BASED ON SELECTIVITY OF THE N & C ACTIVE SITES IN ACE |
| Discussion Leader: Kenneth Bernstein (Cedars-Sinai Medical Centre) |
7:30 pm - 7:55 pm | Oscar Carretero (Henry Ford Hospital)
"Ac-SDKP; Heart Disease & Inflammation" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Ed Sturrock (University of Cape Town)
"Specific Inhibitors of the N- and C-catalytic domains in ACE" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Kenneth Bernstein (Cedars-Sinai Medical Centre)
"Mouse models lacking either N or C terminal catalytic ACE activity" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Ann Tallant (Wake Forest University School of Medicine)
"Angiotensin-(1-7): A Novel Treatment for Cancer" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
9:00 am - 11:20 am | LATE BREAKING ADDITIONS |
| Discussion Leader: Tom Coffman (Duke University and Durham VA Medical Centers) |
9:00 am - 9:20 am | Ulrike Steckelings (Charité - Universitätsmedizin Berlin)
"AT2R non-peptide agonists" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Nicole Gallo-Payet (Université de Sherbrooke, Québec)
"New tools for the type-2 (AT2) receptor" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:45 am | Hitoshi Okamura (Kyoto University)
"Novel molecular link between the circadian clock and hypertension" |
10:45 am - 10:55 am | Discussion |
10:55 am - 11:10 am | Jakob Hansen (University of Copenhagen)
"Biased agonism of the AT1 receptor" |
11:10 am - 11:20 am | Discussion |
11:20 am - 12:30 pm | REFLECTIONS & PREDICTIONS |
11:20 am - 11:30 am | Discussion Leader: Kenneth M. Baker (Texas A&M Health Science Center) |
11:30 am - 11:50 am | Kevin J. Catt (National Institutes of Health)
"Angiotensin Receptors" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Ronald D. Smith (RDS Scientific Solutions LLC)
"Angiotensin & Industry" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | LOCAL RAS & NEW APPLICATIONS |
| Discussion Leader: Richard Re (Ochsner Clinic Foundation) |
7:30 pm - 7:55 pm | Ryuichi Morishita (Osaka University, School of Medicine)
"RAS & Osteoporosis" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Andrew Allen (University of Melbourne)
"Brain Angiotensin, Sympathetic Drive & Hypertension" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 8:55 pm | Yumei Feng (Tulane University)
"Brain ACE2 and hypertension" |
8:55 pm - 9:05 pm | Discussion |
9:05 pm - 9:20 pm | Romer Gonzalez-Villalobos (Tulane University)
"Local ACE is sufficient to generate intrarenal AngII and raise blood pressure" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |