| SATURDAY |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | The B Cell Response |
| Discussion Leader: Jan Terje Andersen (Oslo University Hospital, Norway) |
| 3:15 pm - 3:45 pm | Susan K. Pierce (Laboratory of Immunogenetics, NIAID, NIH, USA)
"The Initiation of Antigen-Driven B Cell Receptor Signaling"
|
| 3:45 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | Antibody Technologies and Therapeutics |
| Discussion Leader: John R. Desjarlais (Xencor, Inc) |
| 5:30 pm - 5:45 pm | Jean-Philippe Bürckert (Centre de Recherche Public de la Santé, Luxembourg)
"Probing the B Cell Repertoire with Low Molecular Weight Hapten Conjugates" |
| 5:45 pm - 5:50 pm | Discussion |
| 5:50 pm - 6:05 pm | Johan Seijsing (Royal Institute of Technology (KTH), Sweden)
"Phage Display Selection of Highly pH Dependent Fusion Tags Binding to the Neonatal Fc Receptor for Extending Serum Half-Life of Biopharmaceuticals"
|
| 6:05 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:25 pm | Filippa Fleetwood (Royal Institute of Technology (KTH), Sweden)
"Surface Display of a Single-Domain Antibody Library on Gram-Positive Bacteria"
|
| 6:25 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:45 pm | Patrick Dennler (Paul Scherrer Institute, Switzerland)
"Towards Homogenous Antibody-Drug Conjugates - Transglutaminase as a Tool for Site-Specific Antibody Modification"
|
| 6:45 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:05 pm | Lois Paton (University of Dundee, UK)
"A Novel Magnetic Fusion Protein for Antibody-Based Cancer Therapy"
|
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:25 pm | Liheng Cai (Harvard University, USA)
"Droplet-Based Microfluidics for High-Throughput Screening of Antibody Secreting Cells"
|
| 7:25 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Antibody Biology and Engineering |
| Discussion Leader: Richard S. Blumberg (Brigham and Women's Hospital and Harvard Medical School, USA) |
| 9:00 am - 9:15 am | Iwan Kustiawan (Sanquin Research and Amsterdam University, the Netherlands)
"Anti-Inflammatory Effect of Dimeric IgG Derived from IVIG"
|
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Johnathan Sockolosky (University of California, USA)
"Cross-Species Ligand Binding to the Neonatal Fc Receptor, FcRn, and the Impact on Plasma Half-Life in Mice Suggest a Species-Specific Role of Beta2-Microglobulin in FcRn Function"
|
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Kathrin Hnida (University of Oslo, Norway)
"Functional Implications of Celiac Autoantibodies-Transglutaminase Interactions"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Jiwon Lee (University of Texas at Austin, USA)
"Identification and Characterization of the Monoclonal Antibodies Comprising the Serological Response to Seasonal Influenza Vaccines" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Arjen Bakker (AIMM Therapeutics)
"Antibody Engineering AIDed by Nature" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Davide Corti (Institute for Research in Biomedicine, Switzerland)
"Dissecting the Human B Cell Response to Pathogens and Self Antigens" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Life as a Scientist - Career Paths and Advice |
| Discussion Leader: Paul Marinec (University of California, USA) |
| Panelists:
- Susan K. Pierce (Laboratory of Immunogenetics, NIAID, NIH, USA)
- Jenny Woof (University of Dundee, UK)
- Richard S. Blumberg (Brigham and Women's Hospital and Harvard Medical School)
- John R. Desjarlais (Xencor, Inc)
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
