Sunday evening, April 25th, 1999 |
18h00 - 19h30 |
Dinner |
19h30 |
J. A. Hoffmann, Chairman, Strasbourg:
Welcome address |
19h45 |
Keynote lecture: T. Ganz, Los Angeles:
The antimicrobial peptides - an overview |
Monday, April 26th |
7h30 |
Breakfast |
9h - 12h30 |
Novel structural aspects, novel methodologies |
Chairs: R.I. Lehrer, Los Angeles & M. Zanetti, Trieste |
- P. Bulet, Strasbourg:
Use of MALDI-TOF mass spectrometry to reveal novel immune-induced peptides in Drosophila (30 min)
- H. Steiner, Stockholm:
Application of differential display PCR techniques to unravel immunity genes (30min)
|
10h |
Coffee break & Photo session |
- S. Natori, Tokyo:
Glutathion-linked antimicrobial peptides from flies (30 min)
- I.F. Nes, Akerhus, Norway:
Ribosomally synthesised antimicrobial peptides in bacteria : A defense system used by bacteria to survive in a competitive environment? (30 min)
- D. Romeo, Trieste:
Comparative studies on cathelicidins and other antimicrobial peptides for the design of efficient antibiotics (30 min)
|
12h30 |
Lunch |
15h30 - 17h30 |
Poster session |
Chairs: C. Bevins, Cleveland; W. Broekaert, Leuven; R. Hancock, Vancouver
Self-service coffee during the session |
17h30 - 19h30 |
Antimicrobial peptides in innate immunity (A) |
Chair: P. Elsbach, New York |
- R.I. Lehrer, Los Angeles:
Antimicrobial peptides in human body fluids (50 min)
- C. Bevins, Cleveland:
Regulation of antimicrobial peptide synthesis in mammals in response to bacterial stimuli (50 min)
|
20h |
Dinner |
Tuesday, April 27th |
7h30 |
Breakfast |
9h - 12h30 |
Antimicrobial peptides in innate immunity (B) |
Chairs: D. Marchini, Siena & R. Gennaro, Trieste |
- J.A. Hoffmann, Strasbourg:
Antimicrobial peptides in insect immunity (50 min)
|
10h |
Coffee break |
- F.C. Kafatos, Heidelberg:
Innate immunity and transmission of parasites by vector insects (50 min)
- A.J. Ouellette, Irvine:
Role of antimicrobial peptides in intestinal defense (50 min)
|
12h30 |
Lunch |
15h30 - 17h30 |
Poster session |
Chairs: C. Bevins, Cleveland; W. Broekaert, Leuven; R. Hancock, Vancouver
Self-service coffee during the session |
17h30 - 19h30 |
Antimicrobial peptides in innate immunity (C) |
Chair: M. Simmaco, Chieti |
- D.F. Klessig, Piscataway:
Signaling in the plant defense response (50 min)
- W. Broekaert, Leuven:
Antimicrobial peptides in plant immunity (50 min)
|
20h |
Dinner |
Wednesday, April 28th |
7h30 |
Breakfast |
8h30 - 11h00 |
The Toll signaling pathway in innate immunity |
Chair: J.A. Hoffmann, Strasbourg |
- F. Bazan, Palo Alto:
A family of human receptors structurally related to Drosophila Toll (50 min)
- B. Beutler, Dallas:
Positional cloning of LPS, the principal susceptibility locus for Gram negative sepsis (50 min)
- S. Akira, Hygo:
MyD88 and TLR-4 KO mice are LPS-hyporesponsive
|
11h |
Coffee break |
11h - 13h00 |
Resistance strategies of microorganisms |
Chairs: C. Bevins, Cleveland & L. Rivas, Madrid |
- E.A. Groisman, St Louis:
Bacterial resistance to antimicrobial peptides (50 min)
- P. Rodriguez-Palenzuela, Madrid:
Bacterial resistance to plant antimicrobial peptides (30 min)
- S.I. Miller, Seattle:
Lipid A modifications and bacterial inducible resistance to antimicrobial peptides (30 min)
|
12h30 |
Lunch |
|
Excursion or Free |
18h - 20h |
Mode of action (A) |
Chair: C. Hetru, Strasbourg |
- R.E.W. Hancock, Vancouver:
Design of improved antimicrobial peptides from natural templates 50min
- D. Aunis, Strasbourg:
New antibacterial peptides involved in neuroimmunity in mammals 50min
|
20h |
Dinner |
Thursday, April 29th |
7h30 |
Breakfast |
9h - 12h30 |
Mode of action (B) |
Chair: M. Zasloff, Philadelphia |
- Y. Shai, Rehovot:
Molecular basis for cell selectivity by antimicrobial peptides (50 min)
- H.G. Sahl, Bonn:
The mode of action of lantibiotics. (50 min)
|
10h |
Coffee break |
- W.M. Shafer, Atlanta:
A proton motive force-driven efflux pump that recognizes antibacterial peptides (30 min)
- P.H. Axelsen, Philadelphia:
Membrane recognition by antimicrobial peptides (50 min)
|
12h30 |
Lunch |
15h -19h30 |
Medical and agricultural applications |
Chair: S. Natori, Tokyo |
- M.A. Zasloff, Philadelphia:
State of the art in commercial peptide applications (30 min)
- J. Fiddes, Sunnyvale:
Medical uses of protegrin-like peptides (30 min)
|
16h |
Coffee break |
- P.R. Abraham, Amsterdam:
Therapeutic potential of designer antimicrobial peptides in pre-clinical models of infection (30 min)
- B. Simons, Leiden:
Antifungal proteins in fungal resistance strategies for plants (30 min)
- J.M. Jaynes, Demeter:
In vivo activity of designed antimicrobial peptides (30 min)
- Round table discussion and business meeting
Chair: J.A. Hoffmann, Strasbourg
|
20h |
Banquet and attribution of the Lifetime Achievement Award for Antimicrobial Peptides to Hans G. Boman |
Friday, April 30th |
7h30 |
Breakfast |
|
Departure |