SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
4:30 pm - 6:00 pm | Social Hour |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Session |
| Discussion Leaders: Andre Ouellette (UC Irvine) & William Shafer (Emory University) |
7:30 pm - 7:45 pm | Welcome |
7:45 pm - 7:55 pm | Career Achievement Award Presentation |
8:00 pm - 8:35 pm | Keynote Address: Michael Zasloff (Georgetown University)
"Antimicrobial peptides in Metazoa" |
8:45 pm - 9:20 pm | Keynote Address: Robert E.W. Hancock (University of British Columbia)
"Beyond Microbicidal Activity" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | AMP Diversity and Phylogenetics |
| Discussion Leader: Charles L. Bevins (UC Davis) |
9:00 am - 9:20 am | Susan E. Douglas (Institute for Marine Biosciences, Halifax)
"Pleurocidins" |
9:30 am - 9:50 am | Carlos Bloch, Jr. (University of Brazil)
"Amphibian AMPs" |
10:00 am - 10:20 am | Timothy A. Mietzner (University of Pittsburgh)
"Lentiviral-derived AMPs" |
10:30 am - 11:15 am | Coffee Break |
11:15 am | Conference Photo |
11:30 am - 11:50 am | Alessandro Tossi (University of Trieste)
"Primate beta-defensin evolution" |
12:00 pm - 12:10 pm | Hans-Henrik Kristensen (Novozymes)
“Plectasin” |
12:15 pm - 12:25 pm | Jurgen Harder (University of Kiel)
“Psoriasin/S100A7” |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session A (M. Ackermann to D. Destoumieux, inclusive) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Regulation of AMP Synthesis |
| Discussion Leader: Robert Bals (Hospital of the University of Marburg) |
7:30 pm - 7:40 pm | Paul B. McCray (University of Iowa)
"An Informatics Approach to Host Defense Gene Discovery in Human Airway Epithelia" |
7:45 pm - 7:55 pm | Frank J. Schmidt (University of Missouri)
"Phage-displayed antimicrobial peptides" |
8:00 pm - 8:20 pm | Lora V. Hooper (University of Texas Southwestern Medical Center)
"Microflora-induced epithelial gene expression" |
8:30 pm - 8:50 pm | Ylva Engstrom (Stockholm University)
"Regulation of AMP expression in Drosophila" |
9:00 pm - 9:20 pm | Bergitta Agerberth (Karolinska Institute)
"Regulation of mammalian AMP expression" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms of AMP action |
| Discussion Leader: Anca M. Segall (San Diego State University) |
9:00 am - 9:20 am | Mira Edgerton (SUNY at Buffalo)
"Fungicidal activity of salivary histatin 5" |
9:30 am - 9:50 am | Karin Thevissen (Catholic University Leuven)
"Plant defensin killing of Neurospora" |
10:00 am - 10:20 am | Hans-Georg Sahl (University of Bonn)
"Lipid II and microbial resistance" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Mary E. Klotman (Mount Sinai School of Medicine)
"α-defensin activity against HIV" |
11:30 am - 11:50 am | Margitte Dathe (Institute of Molecular Pharmacology, Berlin)
"Membrane-peptide interactions" |
| Discussion Leader: Yechiel Shai (Weizmann Institute) |
12:00 pm - 12:05 pm | Maria Luisa Mangoni (La Sapienza University)
"Temporins exert a potent Leishmanicidal activity at the promastigote and amastigote stages" |
12:10 pm - 12:15 pm | Frank Blecha (Kansas State University)
"Peptidoglycan recognition proteins are involved in regulation of beta-defensin-1 expression" |
12:20 pm - 12:25 pm | Mats Andersson (Karolinska Institute)
"Increased diversity of intestinal CRS peptides" |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session B (D. Divine to H-H Kristensen, inclusive) |
6:00 pm | Dinner |
7:30 pm - 9:00 pm | Pathogenesis and Microbial Resistance Mechanisms |
| Discussion leader: John Gunn (The Ohio State University) |
7:30 pm - 7:50 pm | Friedrich Goetz (University of Tübingen)
"Mechanisms of resistance of staphylococci to lysozyme and lysozyme-derived antimicrobial peptides" |
8:00 pm - 8:20 pm | Eric J. Brown (UCSF)
"Mycobacteria and AMP resistance mechanisms" |
8:30 pm - 8:50 pm | Jan Potempa (Jagiellonian University)
"Bacterial proteases and AMPs" |
9:00 pm - 9:30 pm | Open Microphone |
| Free discussion period, 5 min per speaker, maximum of 3-5 overhead transparencies, sign-up will be optional. |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | AMP Model Systems and Innate Immunity |
| Discussion Leader: Tomas Ganz (UCLA) |
9:00 am - 9:20 am | Richard L. Gallo (UCSD)
"CRAMP knockout mice" |
9:30 am - 9:50 am | Gill Diamond (UMDNJ)
"Airway and innate immune mechanisms" |
10:00 am - 10:20 am | Arnold S. Bayer (Harbor-UCLA)
"Bacterial endocarditis and AMPs" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Evelyne Bachère (IFREMER - University of Montpellier II)
"Marine models of infection" |
11:30 am - 11:50 am | Dominique Farrandon (CNRS)
"Innate immune mechanisms in Drosophila" |
| Discussion Leader: Ylva Engstrom (Stockholm University) |
12:00 pm - 12:05 pm | Pieter Hiemstra (Leiden University Medical Center)
"Cigarette smoke condensate increases the expression of beta-defensin-3 in cultured primary bronchial epithelial cells" |
12:10 pm - 12:15 pm | Jan Wehkamp (UC Davis)
"Defensins and Crohn's disease: a molecular link to mucosal barrier" |
12:20 pm - 12:25 pm | Mona Bajaj-Elliott (Institute of Child Health)
"Defensins as bactericidal agents against Neisseria" |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session C (S. Kristian to A. Rinaldi, inclusive) |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting / Elections |
7:30 pm - 9:30 pm | Biochemical/Biophysical Parameters of AMP Action |
| Discussion Leader: Michael Selsted (UC Irvine) |
7:30 pm -7:50 pm | David J. Craik (University of Queensland)
"Cyclotide structures" |
8:00 pm - 8:20 pm | Jacek Lubkowski (NCI Frederick)
"Defensin Structures" |
8:30 pm - 8:50 pm | Alexey Ladokhin (The University of Kansas Medical Center)
"AMP interactions with biomimetic membranes" |
9:00 pm - 9:20 pm | Hans J. Vogel (University of Calgary)
"Structural studies of novel AMPs" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Microbial Responses to Antimicrobials |
| Discussion leader: Andreas Peschel |
9:00 am - 9:20 am | E. Peter Greenberg (University of Iowa)
"Quorum sensing in biofilms" |
9:30 am - 9:50 am | Eduardo A. Groisman (Washington University)
"Bacterial signaling pathways" |
10:00 am - 10:20 am | Steven Projan (Wyeth Research)
"Bacterial gene expression patterns" |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:20 am | Samuel I. Miller (University of Washington)
"Salmonella and AMP resistance mechanisms" |
11:30 am - 11:50 am | Corrella S. Detweiler (University of Colorado)
"In silico studies of molecular pathogenesis" |
| Discussion Leader: Yechiel Shai (Weizmann Institute) |
12:00 pm - 12:05 pm | Martin W. Bader (University of Washington)
"Activation of a bacterial sensor kinase by antimicrobial peptides" |
12:10 pm - 12:15 pm | Emma Andersson Nordahl (Lund University)
"Activation of the complements system generates antibacterial peptides" |
12:20 pm - 12:25 pm | Maire Begley (University College Cork)
"Transcriptional profiling of the Listeria monocytogenes response to the two-peptide lantibiotic lacticin 3147" |
12:30 pm | Lunch |
1:30 pm - 4:30 pm | Free Time |
4:30 pm - 6:00 pm | Poster Session D (M. Roupe to L. Zhang, inclusive) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Finale & Beyond |
| Discussion Leaders: Yechiel Shai (Weizmann Institute) & Ylva Engstrom (Stockholm University) |
7:30 pm - 7:50 pm | Margherita Zanetti (University of Udine)
"Cathelicidin interactions with host cells" |
8:00 pm - 8:20 pm | Timothy J. Falla (Helix Biomedix)
"Peptide delivery to the marketplace" |
8:30 pm - 9:30 pm | Hot Corner: Brief (5 min) presentations featuring news from the lab, controversial issues, or new methods and approaches. Participants will sign up at the conference. There is a maximum of 3-5 overhead transparencies per speaker. |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |