SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:45 pm | Welcome / Introductory Comments by GRC Site Staff |
7:45 pm - 9:30 pm | Keynote Speakers - AMPs: Where we have we been and where are we going? In memory of Hans Boman |
| Discussion Leaders: Richard Gallo (UCSD) and Paul McCray (U. Iowa) |
7:45 pm - 8:25 pm | Michael Karin (UCSD) "Cell Signaling Networks in Innate Immunity" |
8:25 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Charles Bevins (UC Davis) "History and Current Concepts of AMPs in Mucosal Defense" |
9:15 pm - 9:25 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Peptides and other molecules as native antibiotics |
| Discussion Leaders: Tomas Ganz (UCLA) and Nita Salzman (Medical College of Wisconsin) |
9:00 am - 9:20 am | Louisa P. Wu (U Maryland) "Drosophila Innate Immunity" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Eddy Rubin (UC Berkeley) "Genomic discovery tools for antimicrobials" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | William Fenical (Scripps Institute of Oceanography) "Antimicrobials from the sea, diversity and opportunity" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Anne E. Osbourn (UK Sainbury Lab) "Innate Immunity in Plants" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Alexander M Cole (University of Central Florida) "Reawakening Retrocyclins: Ancestral Human Defensins Active against HIV-1" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Natalie L Reynolds (Western General Hospital, MRC Human Genetics Unit) "Exploring Zebrafish Defensins" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Molecular models to understand AMP Function |
| Discussion Leaders: Mei Hong (Iowa State University) and Hans-Georg Sahl (University of Bonn) |
7:30 pm - 7:50 pm | Judy Kim (UCSD) "Understanding AMP-membrane interactions by optical spectroscopy" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Gerard Wong (U of Illinois) "AMP interactions with membranes" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Ka Yee Lee (Univ of Chicago) "Membrane disruption mechanism of antimicrobial peptides" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:30 pm | General Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Regulation of AMP expression |
| Discussion Leaders: Gudmundur Gudmundsson (University of Iceland) and Ylva Engstrom (Stockholm University) |
9:00 am - 9:20 am | Jay Kolls (U Pitt) "IL-17, IL-22 regulation of host defense programs" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Fritz Gombart (LPI/OSU) "Vitamin D and the antimicrobial response" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Jean-Marc Reichhart (ULP - IUF) "Antimicrobial Defense in Drosophila: A Paradigm for Innate Immunity" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Adrian Martineau (Imperial College London) "Induction of AMPs for the Treatment of mycobacterial disease" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Jack B Cowland (Rigshospitalet) "Induction of NGAL expression by co-stimulation with IL-17 and TNF-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor by C/EBP-delta" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Katherine A Radek (University of California, San Diego) "Cholinergic activation regulates epidermal antimicrobial peptide function and susceptibility to invasive bacterial infection" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Microbial Response to AMPs "tricks of the trade" |
| Discussion Leaders: Andreas Peschel (University of Tubingen) and Victor Nizet (University of California) |
7:30 pm - 7:50 pm | Michael Apicella (Univ of Iowa) "How Bacteria Hide from the Host" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Heidi Goodrich-Blair (Univ of Wisconsin) "Mutualistic and pathogenic relationships between Microbes and their Hosts" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Pradeep Singh (Univ of Washington) "Strategies of Pseudomonas for Evasion of Host Defense" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:30 pm | General Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cell and tissue specific roles for AMPs |
| Discussion Leaders: Gill Diamond (UMDNJ) and Andy Ouellette (University of California, Irvine) |
9:00 am - 9:20 am | Allison McDermott (Univ of Houston) "Functions of AMPs in eye disease" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Peter Elias (UCSF) "Stress and the AMP Barrier of the skin" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Mike Welsh (Univ of Iowa) "A porcine model of Cystic Fibrosis" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Lauren Bakaletz (Ohio State Univ) "Middle Ear Host Defense and Otitis Media" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Michelo Simuyandi (University of Zambia) "Helminth infection is associated with down-regulation, even abolition, of a range of antimicrobial peptides in human small intestine" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Neeloffer Mookherjee (University of Manitoba) "Intracellular receptor for immunomodulatory host defence peptides LL-37 and IDR-1 in mononuclear cells" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Non-antimicrobial functions of the AMPs |
| Discussion Leaders: Bob Hancock (University of British Columbia) and Mona Stahle (Karolinska Institutet) |
7:30 pm - 7:50 pm | Joost Oppenheim (NIH) "How AMPs act as Alarmins" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Micheal Gilliet (UT-Houston) "Control of Inflammation by LL37" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Peter Hiemstra (Netherlands) "Function of AMPs in Lung Disease" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:30 pm | General Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:30 am | Understanding biology through the AMPs |
| Discussion Leaders: Birgitta Agerberth (Karolinska Institutet) and Jens Schroder (University of Kiel) |
9:00 am - 9:20 am | Lora Hooper (UT Southwestern) "Microbial regulation of gut AMPs" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Juergen Harder
(University Hospital Schleswig-Holstein) "AMPs in skin biology and diseases" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Ed Hollox (University of Leicester) "Defensin gene copy number polymorphism and disease" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Greg Barsh (Stanford Univ) "Defensin genes and mammalian color variation" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:30 pm | Hot Corner and late breaking news |
| Presenters for short talks and discussion will be selected at the meeting by the Chairs and Vice-Chairs |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Strategies and roadblocks to therapeutic applications |
| Discussion Leaders: Mike Selsted (University of California, Irvine) and Jerry Weiss (University of Iowa) |
7:30 pm - 7:50 pm | Mike Zasloff (Georgetown) "Understanding the Therapeutic Potential of AMPs" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Anton Stuetz (Novartis) "Successful Drug Development in Pharma- Overcoming barriers" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Amram Mor (Technion) "Potent Antimicrobial Peptide Mimetics from Oligoacyllysines (OAKs)" |
8:50 pm - 9:00 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |