| SUNDAY |
| 4:00 pm - 8:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:45 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:45 pm - 9:30 pm | The Rise of the Archaea (in memory of Dr. Carl R. Woese) |
| Discussion Leader: John Reeve (Ohio State University, USA) |
| 7:45 pm - 8:00 pm | Discussion leader's remarks |
| 8:00 pm - 8:50 pm | Rudolf Thauer (Max Planck Institut für terrestrische Mikrobiologie, Germany)
"Archaea and the methane cycle"
|
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:25 pm | Eugene Koonin (National Institutes of Health, USA)
"Evolution of Archaea: the complex ancestors and the origin of eukaryotes"
|
| 9:25 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Replication, recombination and repair |
| Discussion Leader: Patrick Forterre (Université de Paris Sud, France) |
| 9:00 am - 9:10 am | Discussion leader's remarks |
| 9:10 am - 9:25 am | Simonetta Gribaldo (Institut Pasteur, France)
"Phylogenomics of DNA replication in the Archaea: further support for a complex ancestor and the global phylogeny of the third domain of life" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:45 am | Kayleigh Wardell (University of Nottingham, UK)
"Regulation of homologous recombination in Haloferax volcanii"
|
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:15 am | Nick Robinson (University of Cambridge, UK)
"DNA end-resection and double-strand break repair in Sulfolobus solfataricus"
|
| 10:15 am - 10:20 am | Discussion |
| 10:20 am | Group Photo / Coffee Break |
| 11:00 am - 11:25 am | Isaac Cann (University of Illinois at Urbana-Champaign, USA)
"Biochemical, genetic, and biophysical studies on DNA replication in the mesophilic archaeon Methanosarcina acetivorans" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Stuart MacNeill (University of St Andrews, Scotland)
"Untangling the function of the haloarchaeal RecJ family proteins"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Yoshizumi Ishino (Kyushu University, Japan)
"Nucleases for DNA repair in Thermococcals" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Transcription |
| Discussion Leader: Michael Thomm (Universität Regensburg, Germany) |
| 5:30 pm - 5:40 pm | Discussion leader's remarks |
| 5:40 pm - 5:55 pm | Eveline Peeters (Vrije Universiteit Brussel)
"Transcription regulatory networks of Lrp-like transcription factors in Sulfolobus"
|
| 5:55 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:15 pm | Elizabeth Karr (University of Oklahoma)
"Insights into the MsvR protein family" |
| 6:15 pm - 6:20 pm | Discussion |
| 6:20 pm - 6:45 pm | Tom Santangelo (Ohio State University, USA)
"Archaeal transcription regulation in vivo: insights into regulated elongation and termination"
|
| 6:45 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:15 pm | Finn Werner (University College London, UK)
"Archaeal RNA polymerase - evolution and mechanisms"
|
| 7:15 pm - 7:20 pm | Discussion |
| 8:00 pm | Dinner |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CRISPR and viruses |
| Discussion Leader: Ken Stedman (Portland State University, USA) |
| 9:00 am - 9:10 am | Discussion leader's remarks |
| 9:10 am - 9:25 am | Tatiana Demina (University of Helsinki)
"Virus-host interactions in high salinity" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:45 am | Adit Naor (Tel Aviv University)
"The benefits of imperfection - why limited endonuclease homing can increases genetic variation in populations of halophilic archaea" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:15 am | Ziga Zebec (University of Vienna)
"CRISPR-mediated defense mechanisms in Sulfolobus solfataricus" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 11:00 am - 11:25 am | Anita Marchfelder (Universität Ulm, Germany)
"CRISPR/Cas with a grain of salt"
|
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Michael Terns (University of Georgia, USA)
"The CRISPR-Cas systems of Pyrococcus furious"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Malcolm White (University of St Andrews, Scotland)
"Ribonucleoprotein complexes for CRISPR-mediated antiviral defence"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Small RNAs |
| Discussion Leader: Rolf Bernander (Stockholm University, Sweden) |
| 5:30 pm - 5:40 pm | Discussion leader's remarks |
| 5:40 pm - 5:55 pm | Yuchen Liu (Yale University)
"A novel translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogens" |
| 5:55 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:15 pm | Ramesh Gupta (Southern Illinois University)
"Guide RNA-mediated RNA modifications are not essential in Haloarchaea" |
| 6:15 pm - 6:20 pm | Discussion |
| 6:20 pm - 6:45 pm | Ruth Schmitz-Streit (Christian-Albrechts-Universität Kiel, Germany)
"New insights in regulation by sRNAs in Methanosarcina mazei"
|
| 6:45 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:15 pm | Todd Lowe (University of California at Santa Cruz, USA)
"Comparative small RNA-seq across 17 diverse archaea: Unexpected sRNAs suggest new layers of regulation" |
| 7:15 pm - 7:20 pm | Discussion |
| 8:00 pm | Dinner |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Cell envelope |
| Discussion Leader: Karl O. Stetter (Universität Regensburg, Germany) |
| 9:00 am - 9:10 am | Discussion leader's remarks |
| 9:10 am - 9:25 am | Anna-Lena Henche (Max-Planck Institute for Terrestrial Microbiology)
"The assembly and function of cell surface structures in Sulfolobus acidocaldarius" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:45 am | Arnulf Kletzin (Universität Darmstadt)
"Properties of C-Type cytochromes of Ignicoccus hospitalis Localized in Inner and Outer Membranes"
|
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:15 am | Kenneth Jarrell (Queen's University, Canada)
"N-linked glycosylation and surface structures in Methanococcus maripaludis"
|
| 10:15 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 11:00 am - 11:25 am | Mecky Pohlschröder (University of Pennsylvania, USA)
"Diversity and subcellular localization of archaeal secreted proteins"
|
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | David Prangishvili (Institut Pasteur, France)
"Virion egress structures of crenarchaeal viruses"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Robert Gunsalus (University of California Los Angeles, USA)
"Structure and function of Methanosarcina cell envelopes"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Posttranslational modifications |
| Discussion Leader: Fran Perler (New England Biolabs, USA) |
| 5:30 pm - 5:40 pm | Discussion leader's remarks |
| 5:40 pm - 5:55 pm | Dominik Esser (University Duisburg-Essen)
"Protein phosphorylation in Sulfolobus acidocaldarius with focus on the central carbohydrate metabolism"
|
| 5:55 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:25 pm | Li Huang (Chinese Academy of Sciences, China)
"A crenarchaeal protein lysine methyltransferase with relaxed substrate specificity"
|
| 6:25 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:55 pm | Jerry Eichler (Ben Gurion University, Israel)
"N-glycosylation in Haloferax volcanii: Two routes to the same glycoprotein"
|
| 6:55 pm - 7:00 pm | Discussion |
| 7:00 pm - 7:25 pm | Julie Maupin-Furlow (University of Florida, USA)
"Archaeal ubiquitin-like proteins and proteasomes"
|
| 7:25 pm - 7:30 pm | Discussion |
| 7:30 pm - 8:00 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 8:00 pm | Dinner |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Ecology and evolution |
| Discussion Leader: Uri Gophna (Tel Aviv University, Israel) |
| 9:00 am - 9:10 am | Discussion leader's remarks |
| 9:10 am - 9:25 am | Kristina Paul (Max Planck Institute for Terrestrial Microbiology)
"Methanoplasmatales - diversity, ultrastructure, and comparative genomics of the 7th order of methanogens"
|
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:45 am | Alexander Probst (University of Regensburg)
"Archaea on human skin"
|
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:15 am | Tim Urich (University of Vienna, Austria)
"Methanogenic Thermoplasmata - physiology, genomics and ecology of the 7th order of methanogens"
|
| 10:15 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 11:00 am - 11:25 am | Graeme Nicol (University of Aberdeen, Scotland)
"Ecology and physiology of acidophilic ammonia oxidisers" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Rachel Whitaker (University of Illinois at Urbana-Champaign, USA)
"Genome diversity shaped by evolution and recombination S. islandicus"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Thijs Ettema (Uppsala University, Sweden)
"Single-cell genomics approaches to elucidate the archaeal ancestry of eukaryotes"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:10 pm | Metabolism |
| Discussion Leader: Haruyuki Atomi (Kyoto University, Japan) |
| 5:30 pm - 5:40 pm | Discussion leader's remarks |
| 5:40 pm - 6:05 pm | Bettina Siebers (University of Duisburg-Essen, Germany)
"Challenges and potential of life at high temperature" |
| 6:05 pm - 6:10 pm | Discussion |
| 6:10 pm - 6:35 pm | Mike Adams (University of Georgia, USA)
"Temperature-dependent metabolic engineering of Pyrococcus furiosus"
|
| 6:35 pm - 6:40 pm | Discussion |
| 6:40 pm - 7:05 pm | Bill Metcalf (University of Illinois at Urbana-Champaign, USA)
"Electron transport in Methanosarcina"
|
| 7:05 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:30 pm | Concluding Remarks: Bill Metcalf (University of Illinois at Urbana-Champaign, USA) |
| 8:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |