| Sunday |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | Keynote Session: Archaeal Biology Nearly Two Decades After the First Genome |
| Discussion Leader: Eugene Koonin (National Institutes of Health, USA) |
| 7:40 pm - 7:50 pm | Introduction by Discussion Leader |
| 7:50 pm - 8:30 pm | Gerhard Gottschalk (Georg-August University of Gottingen, Germany) "En Route in the Archaeal World" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:20 pm | Anna-Louise Reysenbach (Portland State University, USA) "New Insights into the Ecology and Genomics of Novel Cultivated Nanoarchaeota" |
| 9:20 pm - 9:30 pm | Discussion |
| Monday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Replication, Recombination, and Repair |
| Discussion Leader: Zvi Kelman (University of Maryland, USA) |
| 9:00 am - 9:10 am | Introduction by Discussion Leader |
| 9:10 am - 9:35 am | Stephen Bell (Indiana University, USA) "Initiation of DNA Replication in Sulfolobus" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 10:05 am | Andrew Gardner (New England Biolabs, USA) "Insights into Thermococcus Replisome Dynamics in Leading and Lagging Strand Synthesis" |
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:35 am | Nick Robinson (University of Cambridge, United Kingdom) "Mechanisms of Double-Strand Break Repair in the Thermophilic Archaea" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 11:10 am | Coffee Break |
| 11:10 am - 11:35 am | David Crowley (Assumption College, USA) "Transcription-Coupled Repair of UV Damage in Halobacterium sp. NRC-1 and Haloferax volcanii" |
| 11:35 am - 11:40 am | Discussion |
| 11:40 am - 11:55 am | Neta Altman (Tel Aviv University, Israel) "Using Natural Isolates to Investigate Patterns of Homologous Recombination in Halophilic Archaea" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Thijs Ettema (Uppsala University, Sweden) "A Missing Link in the Archaea to Eukaryote Transition" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Transcription |
| Discussion Leader: Finn Werner (University College London, United Kingdom) |
| 7:30 pm - 7:45 pm | Introduction by Discussion Leader |
| 7:45 pm - 8:05 pm | Thomas Santangelo (Colorado State University, USA) "Structural Insights into the Archaeal Transcription Cycle" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:30 pm | Dina Grohmann (University of Regensburg, Germany) "Exploring the Conformational Space Sampled by the RNA Polymerase Clamp Domain" |
| 8:30 pm - 8:35 pm | Discussion |
| 8:35 pm - 8:55 pm | Eveline Peeters (Vrije Universiteit Brussel, Belgium) "Transcription Regulation of Fatty Acid Metabolism in Sulfolobus acidocaldarius" |
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:10 pm | Fabian Blombach (University College London, United Kingdom) "A Dimeric TFE Transcription Factor from Sulfolobus Combines Features of the Eukaryotic RNA Polymerase II and III Machineries" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Mar Martinez-Pastor (Duke University, USA) "Transcription Factor Network Involved in the Regulation of Iron Homeostasis in Archaea" |
| 9:25 pm - 9:30 pm | Discussion |
| Tuesday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CRISPR and Viruses |
| Discussion Leader: Michael Terns (University of Georgia, USA) |
| 9:00 am - 9:10 am | Introduction by Discussion Leader |
| 9:10 am - 9:35 am | Eugene Koonin (National Institutes of Health, USA) "Novel Mobile Genetic Elements in Archaea and Their Contribution to the Evolution of CRISPR-Cas Adaptive Immunity" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 10:05 am | Malcolm White (St. Andrews University, United Kingdom) "The Mechanism of New Spacer Integration in the CRISPR System for Antiviral Defense" |
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:30 am | Uri Gophna (Tel Aviv University, Israel) "CRISPR and Inter-Species Mating in Archaea" |
| 10:30 am - 10:35 am | Discussion |
| 10:35 am - 11:05 am | Coffee Break |
| 11:05 am - 11:30 am | Mark Young (Montana State University, USA) "New Viruses, New Surprises" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 12:00 pm | David Prangishvili (Institut Pasteur, France) "Biology of the Rudivirus SIRV2, a Model for the Study of Virus-Host Interactions in Hyperthermophilic Archaea" |
| 12:00 pm - 12:05 pm | Discussion |
| 12:05 pm - 12:25 pm | Rachel Whitaker (University of Illinois, USA) "Coevolutionary Impact of Viruses on Sulfolobus islandicus" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Cell Biology and Ecology |
| Discussion Leader: Anna-Louise Reysenbach (Portland State University, USA) |
| 7:30 pm - 7:40 pm | Introduction by Discussion Leader |
| 7:40 pm - 8:05 pm | Sonja-Verena Albers (University of Freiburg, Germany) "Regulation of Archaellum Assembly" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:35 pm | Jose de la Torre (San Francisco State University, USA) "Ammonia-Oxidizing Archaea in Hydrothermal Ecosystems: Ecology, Metabolism and Evolution" |
| 8:35 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:05 pm | Victoria Orphan (California Institute of Technology, USA) "Deconvolving the Ecological Physiology of Uncultured Methanotrophic ANME Archaea and Their Symbiotic Bacterial Partners" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Anna Perevalova (Winogradsky Institute of Microbiology, Russia) "Thermoplasmata-Related Thermophilic Methanogens from Kamchatka Hot Springs" |
| 9:25 pm - 9:30 pm | Discussion |
| Wednesday |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Non-Coding RNAs |
| Discussion Leader: Patrick Dennis (Howard Hughes Medical Institute, Janelia Research Campus, USA) |
| 9:00 am - 9:10 am | Introduction by Discussion Leader |
| 9:10 am - 9:35 am | Beatrice Clouet D'Orval (University of Toulouse, France) "Archaeal β-CASP Ribonucleases" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 10:05 am | Cameron Mura (University of Virginia, USA) "Archaeal (and Bacterial) Sm-Like Proteins, from Tiny RNAs to Huge Protein Cages" |
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:35 am | Lennart Randau (Max Planck Institute for Terrestrial Microbiology, Germany) "RNA Circularization Restores SRP RNA Functionality" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 11:10 am | Coffee Break |
| 11:10 am - 11:35 am | Joerg Soppa (Goethe University, Germany) "Small Regulatory RNAs in Haloarchaea: Classes, Biological Functions, and Molecular Mechanisms" |
| 11:35 am - 11:40 am | Discussion |
| 11:40 am - 12:00 pm | Diego Gelsinger (Johns Hopkins University, USA) "sRNA-Mediated Regulation of Oxidative Stress Response in Haloarchaea" |
| 12:00 pm - 12:05 pm | Discussion |
| 12:05 pm - 12:25 pm | Lauren Lui (University of California, Santa Cruz, USA) "Atypical snoRNA-Like RNAs Found Across Archaea" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
| 7:30 pm - 9:30 pm | Metabolism and Post-Translational Modifications |
| Discussion Leader: Bettina Siebers (University of Duisburg-Essen, Germany) |
| 7:30 pm - 7:40 pm | Introduction by Discussion Leader |
| 7:40 pm - 8:00 pm | Haruyuki Atomi (Kyoto University, Japan) "Nucleoside Degradation Systems in Archaea" |
| 8:00 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:25 pm | Julie Maupin-Furlow (University of Florida, USA) "Archaeal Ubiquitin-Proteasome System in Regulation and Protein Quality Control" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Laurence Prunetti (University of Florida, USA) "Comparative Genomic Leads to the Elucidation of a Variant Pathway for EIF5A Modification in Halophilic Archaea" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Biswarup Mukhopadhyay (Virginia Tech, USA) "Thioredoxin Systems of Methanogenic Archaea: Evolutionary and Metabolic Implications" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Michael Rother (Technische Universität Dresden, Germany) "Conversion of Pyruvate and Glucose to Methane by Methanosarcina acetivorans" |
| 9:25 pm - 9:30 pm | Discussion |
| Thursday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Genomics and Evolution |
| Discussion Leader: Patrick Forterre (Pasteur Institute, France) |
| 9:00 am - 9:10 am | Introduction by Discussion Leader |
| 9:10 am - 9:35 am | Shijulal Nelson-Sathi (University of Dusseldorf, Germany) "Origins of Major Archaeal Clades Correspond to Gene Acquisitions from Bacteria" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 10:05 am | Guillaume Borrel (University College Cork, Ireland) "Methanomassiliicoccales, Characterization of a Novel Order of Methanogens Associated to the Human Gut Microbiome" |
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:35 am | Kira Makarova (National Center for Biotechnology Information, USA) "Clusters of Orthologous Genes and Comprehensive Analysis of Gene Neighborhoods in Archaea" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 11:10 am | Coffee Break |
| 11:10 am - 11:35 am | Patrick Forterre (Pasteur Institute, France) "Mobile Elements and Genome Evolution in Thermococcales" |
| 11:35 am - 11:40 am | Discussion |
| 11:40 am - 12:00 pm | William Inskeep (Montana State University, USA) "Geochemical Controls on the Distribution and Function of Hyperthermophilic Archaea in Yellowstone National Park" |
| 12:00 pm - 12:05 pm | Discussion |
| 12:05 pm - 12:25 pm | Yue Guan (King Abdullah University of Science and Technology, Saudi Arabia) "Exploring Archaeal Genomes from the Deep-Sea Brine Lakes of the Red Sea" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | Biotechnology and Biomedical Research |
| Discussion Leader: Frank Robb (Institute of Marine and Environmental Technology, University of Maryland, Baltimore, USA) |
| 5:30 pm - 5:40 pm | Introduction by Discussion Leader |
| 5:40 pm - 6:00 pm | Tyler Johnson (University of Nebraska-Lincoln, USA) "Experimental Microbial Evolution of Archaea: Genome to Phenome" |
| 6:00 pm - 6:05 pm | Discussion |
| 6:05 pm - 6:25 pm | Zhe Lyu (University of Georgia, USA) "Engineering the Autotrophic Methanococcus maripaludis for Geraniol Production" |
| 6:25 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:55 pm | Frank Robb (Institute of Marine and Environmental Technology, University of Maryland, Baltimore, USA) "Archaeal Model Systems for Human Inherited Diseases and Vaccines" |
| 6:55 pm - 7:00 pm | Discussion |
| 7:00 pm - 7:20 pm | Corinna Bang (Christian-Albrechts-University of Kiel, Germany) "Methanoarchae and the Human Immune System" |
| 7:20 pm - 7:25 pm | Discussion |
| 7:25 pm - 7:30 pm | Closing Remarks |
| 8:00 pm | Dinner |
| Friday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |