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Artificial Molecular Switches and Motors

Gordon Research Conference

Design, Synthesis, Power and Control

June 18 - 23, 2023

Chairs

and

Vice Chairs

and

Colby-Sawyer College

541 Main Street

New London, New Hampshire, United States

Venue and Travel Information

Conference Description

The Artificial Molecular Switches and Motors GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Macroscopic machines have enabled the industrial revolution and have profoundly changed how humans live, work, and interact with each other. They have also been crucial for the enormous progress of chemistry, which has recently set out to build and study the tiniest machines at the molecular level. The molecular switches, motors, and machines resulting from these efforts have already reached a high level of sophistication and their operational principles and basic modalities are reasonably well understood. The question is how the molecular-scale machinery can be developed further, produced on scale, and put to work to have an impact as transformative as their macroscopic counterparts.

Related Meeting

This GRC will be held in conjunction with the "Artificial Molecular Switches and Motors" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	From Small Molecules to Complex Tasks Discussion Leader:
7:40 pm - 7:50 pm	Introduction by Discussion Leader
7:50 pm - 8:25 pm	"Mechanochemistry of Molecular Machines"
8:25 pm - 8:40 pm	Discussion
8:40 pm - 9:15 pm	"Lessons Learned Trying to Tame the Complexity of DASA: From Molecules to Devices"
9:15 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Early-Career Investigator Presentations Discussion Leader:
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:40 am	"Light, Molecule, Action! Optochemical Tools for Interrogating Biological Processes"
9:40 am - 9:50 am	Discussion
9:50 am - 10:05 am	"Photo-Responsive Soft Materials for Solar Oscillators and Soft Machines"
10:05 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:10 am	"Chemically-Fueled Motion and Organization of Droplets"
11:10 am - 11:20 am	Discussion
11:20 am - 11:45 am	"Photoswitchable Dynamic Covalent Bonds for Reversibly Photocontrolled Soft Materials"
11:45 am - 11:55 am	Discussion
11:55 am - 12:20 pm	"Designing Organic Photoswitches for Optically-Controlled Phase Transitions and a Sustainable Future"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
3:00 pm - 4:00 pm	The GRC Power Hour™ The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring. Organizer:
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Molecular Switches and Motors at Surfaces Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:20 pm	"Controlling and Resolving Chemical Reactions, Electronic Configuration, and Charge States in Single Molecules by Atomic Force Microscopy"
8:20 pm - 8:35 pm	Discussion
8:35 pm - 9:15 pm	"Understanding Conduction, Motion, Heat, and Spin in Molecules and Interfaces"
9:15 pm - 9:30 pm	Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Designing Molecular Switches Discussion Leader:
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:55 am	"Hydrazone-Based Switches and Functional Materials"
9:55 am - 10:10 am	Discussion
10:10 am - 10:40 am	Group Photo / Coffee Break
10:40 am - 11:20 am	"New Approaches for the Discovery of Photopharmacological Agents"
11:20 am - 11:35 am	Discussion
11:35 am - 12:15 pm	"Discovering and Understanding Photoswitching Mechanisms with Computations and Machine Learning"
12:15 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Switches, Motors and Their Environment Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:20 pm	"Phenylazothiazoles as Visible-Light Photoswitches"
8:20 pm - 8:35 pm	Discussion
8:35 pm - 9:15 pm	"From Molecular Motion to Macroscopic Actuation"
9:15 pm - 9:30 pm	Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Taking Molecular Switches and Motors from and to Biology Discussion Leader:
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:45 am	"Self-Assembling pH-Responsive Block Copolymers as Nanocarriers for NIR-Emissive Fluorophores"
9:45 am - 9:55 am	Discussion
9:55 am - 10:25 am	"Nucleic Acid Based Molecular Switches: Applications in Nanorobotics and Synthetic Biology"
10:25 am - 10:35 am	Discussion
10:35 am - 11:10 am	Coffee Break
11:10 am - 11:40 am	"From molecular switches to switchboards and circuits with nucleic acids"
11:40 am - 11:50 am	Discussion
11:50 am - 12:20 pm	"Structural Insights into Muscle Biomechanics and Bacterial Injection Machines"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Topological Molecular Switches Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:20 pm	"Mechanical Stereochemistry and Controlled Molecular Motion"
8:20 pm - 8:35 pm	Discussion
8:35 pm - 9:15 pm	"Molecular Flip Flops: Optical Switching Without Photochrome"
9:15 pm - 9:30 pm	Discussion
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Soft Materials and Robotics Discussion Leader:
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:55 am	"Optical-Gating of Spin-based Quantum States for QISE"
9:55 am - 10:10 am	Discussion
10:10 am - 10:40 am	Coffee Break
10:40 am - 11:20 am	"From Scientific Curiosity to Prospective Business: A Case Study on Azobenzene-Based Humidity Sensing"
11:20 am - 11:35 am	Discussion
11:35 am - 12:15 pm	"Molecular Machines and Responsive Microswimming Robots Using Structural DNA Nanotechnology"
12:15 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Last Night of Molecules in Action Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:10 pm	"Sensitized Disequilibration of Azo Switches"
8:10 pm - 8:25 pm	Discussion
8:25 pm - 8:35 pm	"Photo Responsive Control of Protein Complex Size Via Electrostatic Self-Assembly"
8:35 pm - 8:40 pm	Discussion
8:40 pm - 8:50 pm	"Fabrication And Characterization of Polycarbonate Substrates for High Yield Assembly of Multicomponent Biohybrid Microrobots"
8:50 pm - 8:55 pm	Discussion
8:55 pm - 9:05 pm	"Optical Control of Membranes Enabled by Photo lipids"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:20 pm	"Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photo switching Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision"
9:20 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	Closing Remarks
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

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Conference History Artificial Molecular Switches and Motors (GRS)

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