Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Current Direction of Mechanical Circulatory Support (MCS) – What We Have Learned Since REMATCH (Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure)
This opening session will summarize recent clinical trial successes and failures, and provide a critical analysis of the remaining obstacles limiting the growth of MCS.
Discussion Leader: Robin Bostic (Abbott, USA)
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:05 pm
Introduction by Discussion Leader: State of the VAD Nation
8:05 pm - 8:20 pm
Mandeep Mehra (Brigham and Women's Hospital, USA)
"Remaining Obstacles Limiting the Field of MCS: A Frank Assessment of Where We Are Now with Adverse Events (and Where We Would Be Without Them)"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Mark Carlson (Abbott, USA)
"Growth of MCS Within the Larger Medical Device Field"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Lisa Ensz (Medtronic, USA)
"The Impact of Next Generation Devices on Physicians and Patients"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion: Recent Evolution of MCS Industry
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Optimizing MCS Patient and Lifestyle Management
Determinants of exercise tolerance and capacity and how they can be coordinated for efficacy and patient compliance. Insight into MCS physiology from the Total Artificial Heart community. Home health monitoring as well as decision-making tools for patient management.
Discussion Leaders: Lynne Warner Stevenson (Brigham and Women's Hospital, USA) and Kartik Sundareswaran (Abbott, USA)
9:00 am - 9:15 am
Donna Mancini (Mount Sinai Hospital, USA)
"Exercise Tolerance and Capacity"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Libera Fresiello (KU Leuven, Belgium)
"Exercise Hemodynamics, Analysis and Modeling"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
General Discussion: Exercise and MCS
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:45 am
Keyur Shah (Virginia Commonwealth University, USA)
"Clinical Considerations and Patient Selection for the Total Artificial Heart"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
Daniel Tang (Virginia Commonwealth University, USA)
"Surgical Challenges of the Total Artificial Heart"
11:00 am - 11:05 am
Discussion
11:05 am - 11:15 am
General Discussion: Total Artificial Heart
11:15 am - 11:30 am
Amrut Ambardekar (University of Colorado, USA)
"Decision-Making Tools for LVAD Patient Management"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
Kathleen Grady (Northwestern University, USA)
"VAD Self-Care: Providing a Patient and Caregiver-Centric Focus"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
Michael Petty (University of Minnesota Medical Center, USA)
"Psychosocial Risk Factors and Implications for VAD Self-Care"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion: Patient Case Studies
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Physiology of Adverse Events that Are Limiting the Growth of Assisted Circulation
The obstacles of hemocompatibility and right ventricular failure are discussed from a wide range of perspectives.
Discussion Leaders: Ulrich Jorde (Montefiore Medical Center / Albert Einstein College of Medicine, USA) and Salim Olia (University of Pittsburgh, USA)
7:30 pm - 7:45 pm
Gabriel Sayer (University of Chicago Medical Center, USA)
"RV Failure Post Device Implantation; Assessment and Novel Therapies"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
David Farrar (Abbott, USA)
"RV Function, RV Failure, and RVADs"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
General Discussion: Right Ventricular MCS
8:20 pm - 8:35 pm
Georg Wieselthaler (University of California, San Francisco, USA)
"The Next Generation of VADs: How Much Better Will They Be?"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Lisa Baumann Kreuziger (BloodCenter of Wisconsin, USA)
"Balancing Bleeding and Clotting in MCS Patients: A Mechanistic View"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
Nir Uriel (University of Chicago, USA)
"Angiogenesis in Patients Supported with Continuous Flow Pumps"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion: Hemocompatibility
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Selecting and Managing the Right Patient for the Right Outcome
Discussion Leaders: Thorsten Siess (Abiomed Europe GmbH, Germany) and Victor Pretorius (University of California, San Diego, USA)
9:00 am - 9:15 am
O. H. Frazier (Texas Heart Institute, USA)
"The Future Role of MCS in Advanced Heart Failure"
9:15 am - 9:30 am
Discussion
9:30 am - 9:45 am
James Kirklin (University of Alabama at Birmingham, USA)
"InterMACS"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:45 am
Jennifer Conway (University of Alberta, Canada)
"Selection and Treatment: Pediatric HF Patients Are Not Small Adult HF Patients"
10:45 am - 11:00 am
Discussion
11:00 am - 11:15 am
Stavros Drakos (University of Utah, USA)
"Recent Developments in Myocardial Recovery"
11:15 am - 11:20 am
Discussion
11:20 am - 11:35 am
Eduardo Rame (University of Pennsylvania, USA)
"Myocardial Recovery May Be a Dead-End Target"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
General Discussion: Myocardial Recovery
12:00 pm - 12:15 pm
Eric Adler (University of California, San Diego, USA)
"Bi-VADs"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Future of Intelligent Pumping
Discussion Leaders: Heinrich Schima (Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria) and James Kirklin (University of Alabama at Birmingham, USA)
7:30 pm - 7:45 pm
Francesco Moscato (Medical University of Vienna, Austria)
"24/7 Beat-to-Beat Monitoring of VAD-Patients: Clinical Data Underline the Importance of Smart Pumps"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
Bryan Lynch (ReliantHeart Inc., USA)
"Experiences with Remote Home Monitoring with the Reliant Heart"
8:15 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Kevin Bourque (Abbott, USA)
"Integration of CardioMEMS Pressure Sensor into VAD Systems"
8:45 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
Shaun Gregory (Griffith University, Australia)
"Smart Pump Control - What Has Been Done, How to Optimize, and What Are the Open Questions"
9:15 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Academic Innovations and Prognostic Indicators
Novel approaches to overcoming the obstacles of MCS from academic labs in a variety of areas.
Discussion Leaders: Steven Koenig (University of Louisville, USA) and Francis Pagani (University of Michigan, USA)
9:00 am - 9:15 am
Daniel Tamez (Medtronic, USA)
"Next Generation Ventricular Assist Devices and Diagnostics, Industry's Collaboration with Academia"
9:15 am - 9:30 am
Discussion
9:30 am - 9:45 am
Ellen Bass (Drexel University, USA)
"Human Factors in MCS Design"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:45 am
Karen Christman (University of California, San Diego, USA)
"Biomaterials for Improving Myocardial Function"
10:45 am - 11:00 am
Discussion
11:00 am - 11:15 am
Daniel Zimpfer (Medical University of Vienna, Austria)
"A Less Invasive Surgical Approach for MCS"
11:15 am - 11:30 am
Discussion
11:30 am - 11:45 am
Amy Prieto (Colorado State University, USA)
"Novel Battery Design"
11:45 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Salim Olia (University of Pittsburgh, USA)
"Barriers to Patient and Mainstream Acceptance of VADs: Observations of a Clinical Engineer"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Jayant Raikhelkar (University of Chicago, USA)
"Ramp Test in LVAD Patients Hemodynamics and Outcome"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Industry Innovations: New Advances in LVAD Pulsatility, Miniaturized MCS Devices, and Total Artificial Heart Design
Many small companies have developed novel designs that may be game-changers in the reduction of serious adverse events, short technical overviews of late-breaking innovations will be presented.
Discussion Leaders: Kurt Dasse (HBeat Medical, USA), Changfu Wu (Food and Drug Administration, USA) and Michael Ashenuga (Medtronic, USA)
7:30 pm - 7:40 pm
Richard Wampler (Oregon Health and Science University, USA)
"Current Innovations in Device Design"
7:40 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
Carl Botterbusch (CorWave SA, France)
"Corwave LVAD - the 'Fishtail' Membrane, a Novel Approach to Pumping, Promises to Reduce Adverse Events"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
Sonna Patel-Raman (NuPulseCV, USA)
"NuPulse iVAS - A Minimally Invasive Long-Term Counterpulsation Device for Treatment of CHF"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Vegard Tuseth (NuHeart, Norway)
"The Nuheart Fully Percutaneous LVAD"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Michael Zilbershlag (Leviticus Cardio, Israel)
"Coplanar Wireless Energy Transfer (CET) System for Fully Implanted VAD"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Global Future of MCS
What opportunities are there for growing the application of
MCS in health care? What are the economics of MCS and heart failure predicted
to be over the next 10-15 years?
Discussion Leaders: Timothy Baldwin (National Heart, Lung, and Blood Institute, NIH, USA) and Emma Birks (University of Louisville, USA)
9:00 am - 9:15 am
Jerry Heatley (St. Jude Medical / Thoratec , USA)
"Clinical Trial Design"
9:15 am - 9:30 am
Discussion
9:30 am - 9:45 am
Robert Kormos (University of Pittsburgh Medical Center, USA)
"Global Initiatives in Standardization of MCS Therapy"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:45 am
Kurt Dasse (HBeat Medical, USA)
"Emerging Markets for MCS: Pediatrics"
10:45 am - 10:50 am
Discussion
10:50 am - 11:05 am
Christina Vanderpluym (Boston Children's Hospital, USA)
"How PediMACS Will Enlighten Us"
11:05 am - 11:10 am
Discussion
11:10 am - 11:30 am
General Discussion: Pediatric MCS
11:30 am - 11:45 am
James Long (INTEGRIS Advanced Cardiac Care, USA)
"Emerging Markets for MCS: India"
11:45 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
Yuriy Pya (National Research Center for Cardiac Surgery, Kazakhstan)
"Emerging Markets for MCS: Kazakhstan"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Catalyzing the Next Steps to Solving Major MCS Challenges
Wide-ranging perspectives from experiences investigators
will challenge the assisted circulation community to define priorities for
immediate study as well as long-term direction.
Discussion Leader: John Watson (University of California, San Diego, USA)
7:30 pm - 7:45 pm
Tom Vassiliades (Medtronic, USA)
"Role of MCS in an Integrated Health Care System"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
Dawn Christensen (Innovative Program Solutions, LLC, USA)
"Social Media as Support for MCS Patients"
8:15 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
James Antaki (Carnegie Mellon University, USA)
"MCS Moonshot"
8:45 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
Christopher Hayward (St. Vincent's Hospital, Australia)
"Patient Pump Interaction - Clinical Insights from Waveforms"
9:15 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure
