Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Chronic Heart Failure: The New Treatments
In this session experts on chronic heart failure will address the newest and upcoming treatments for chronic heart failure. A prediction of the epidemiology of chronic heart failure will be sketched. This session should allow the field of mechanical support to project the treatment opportunities, specifically for the NYHA Class 3 patients.
Discussion Leader: Daniel Burkhoff (Columbia University, USA)
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:10 pm
Douglas Mann (Washington University School of Medicine in St. Louis, USA)
"Medical and Device-Based Therapies for Heart Failure with Reduced Ejection Fraction"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
David Farrar (Abbott, USA)
"The Role of Invasive Hemodynamic Monitoring in the Future Management of Chronic Heart Failure"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Eduardo Rame (University of Pennsylvania, USA)
"Changing Landscape of Chronic Heart Failure, Its Health Economics and the Role of LVAD"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Optimizing LVADs Beyond the Pump
Several opportunities exist to optimize the current LVADs. Devices can be sensorized allowing better adaptation to exercise. New technologies to remotely control the devices are upcoming and will be addressed. An analysis of current common use errors gives insight in the aspects to develop.
Discussion Leaders: Pascal Leprince (Groupe Hospitalier Pitié-Salpétrière, France) and Heinrich Schima (Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria)
9:00 am - 9:20 am
Mike Hess (Medtronic, Inc., USA)
"Go to the Head of the Class: Smart Pumps Take the Lead"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Marek Druzdzel (University of Pittsburgh, USA)
"Artificial Intelligence and How It Can Support Decisions"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Manreet Kanwar (Allegheny General Hospital, USA)
"The Potential of Machine Learning in Risk Stratification and Decision Making"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Jan Schmitto (Hannover Medical School, Germany)
"Vision on Implant Techniques and How They Can Change the Future of LVADs"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Changfu Wu (U.S. Food and Drug Administration, USA)
"FDA Use Errors MAUDE Database"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Carlo Bartoli (University of Pennsylvania, USA)
"Should We Care About VWF Degradation in LVAD Patients ?"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Totally Implantable Devices
The ultimate goal, a totally implantable device, can be obtained in the coming years. The available and missing technology will be presented and discussed.
Discussion Leader: Robert Dowling (Penn State Health Milton S. Hershey Medical Center, USA)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
Ivan Netuka (Institute of Clinical and Experimental Medicine (IKEM), Czech Republic)
"First Experience with a Fully Implantable VAD"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
Richard Wampler (Oregon Health and Science University, USA)
"A Reality Check on Fully Implantable Systems"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:35 pm
Mark Carlson (Abbott, USA)
"The Vision on Totally Implantable Technology with Heartmate"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am
Group Photo
9:00 am - 12:30 pm
Management of LVAD Patients
Improvement of patient management is obtained by several incremental steps. New generalized adverse event definitions are presented to standardize globally patient management.
Discussion Leaders: Robert Kormos (University of Pittsburgh Medical Center, USA) and Daniel Zimpfer (Medical University of Vienna, Austria)
9:00 am - 9:10 am
Introduction by Discussion Leader: A Perspective on How Adverse Events Changed
9:10 am - 9:30 am
Kenji Yamazaki (Hokkaido Cardiovascular Hospital, Japan)
"The Secret Behind the Japanese Results"
9:30 am - 9:45 am
Discussion
9:45 am - 10:05 am
Thomas Schloeglhofer (Medical University of Vienna, Austria)
"The Contibution of LVAD Data to Patient Management"
10:05 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
Christopher Hayward (St. Vincent's Hospital, Australia)
"In Vivo PV Loops and How They Can Optimize Patient Management"
11:10 am - 11:25 am
Discussion
11:25 am - 11:45 am
Tonya Elliott (MedStar Heart & Vascular Institute, USA)
"The Patient Perspective and the Role of Frailty"
11:45 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
Evgejij Potapov (German Heart Center Berlin, Germany)
"Addressing the Ambulatory Heart Failure Patient: EACTS Expert Consensus on Long-Term Mechanical Circulatory Support"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Management of Stroke
Stroke is the most feared complication and its occurrence seems resistant to technological improvements. In this session pathways to increase pump design and patient management to prevent stroke will be discussed.
Discussion Leader: Patti Massicotte (Stollery Children's Hospital, University of Alberta, Canada)
6:00 pm - 6:20 pm
James Kirklin (University of Alabama at Birmignham, USA)
"The Incidence, Impact and Devastation of Strokes During CF LVAD Support"
6:20 pm - 6:40 pm
Discussion
6:40 pm - 7:00 pm
Friedrich Kaufmann (Deutsches Herzzentrum Berlin, Germany)
"Does the Inflow Cannula Play a Role?"
7:00 pm - 7:20 pm
Discussion
7:20 pm - 7:40 pm
Daniel Licht (Children's Hospital of Philadelphia, USA)
"Cerebral Blood Flow and VADs"
7:40 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Recovery of Heart Failure
Several new approaches are in evolution to optimize cardiac recovery during acute myocardial infarction. New insights of the underlying mechanism and opportunities to influence these mechanisms will be discussed. Recovery of the heart function starts with reversed remodeling. New insight in the mechanism of reversed remodeling can help to develop strategies and technologies to create an improved outcome.
Discussion Leaders: Stavros Drakos (University of Utah Health, USA) and Eduardo Rame (University of Pennsylvania, USA)
9:00 am - 9:15 am
Introduction by Discussion Leader: The Mechanism of Reversed Remodeling
9:15 am - 9:35 am
Steven Jacobs (Universitair Ziekenhuis Leuven, Belgium)
"Unloading Strategies to Optimize Reverse Remodeling"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Palak Shah (Inova Heart and Vascular Institute, USA)
"Drilling Down on Molecular Mechanisms and Biomarkers to Predict Ventricular Recovery"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Navin Kapur (Tufts University School of Medicine, USA)
"The Principle of Stemi LV Unloading and the Potential to Recover Hearts"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
Sebastian Schulte-Eistrup (Schüchtermann Klinik, Germany)
"The Impella 5.5 Axillary Approach"
11:35 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Diyar Saeed (Leipzig Heart Center, Germany)
"We Can Optimize VA-ECMO Patients and Bridge Them Successfully to Long Term LVAD"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion: The Platform for Myocardial Recovery in Advanced Cardiogenic Shock
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Miniaturization of LVADs and Pediatric Use
The field of pediatric LVADs has specific challenges. This session will address the newest management and devices to improve mechanical support for children. The technicial challenge to miniaturize the devices for children has an enormous potential to address the less sick NYHA Class 3 patients. New developments in this field will be presented.
Discussion Leaders: John Woodard (Berlin Heart GmbH, Germany) and Salim Olia (University of Pennsylvania, USA)
6:00 pm - 6:20 pm
Antonio Amodeo (Bambino Gesù Pediatric Hospital, Italy)
"Novel Experience with the Pediatric Jarvik"
6:20 pm - 6:35 pm
Discussion
6:35 pm - 6:55 pm
Yves d'Udekem (The Royal Children's Hospital, Australia)
"The Failing Fontan: What Is Coming and How Can It Be Addressed?"
6:55 pm - 7:10 pm
Discussion
7:10 pm - 7:30 pm
Thorsten Siess (Abiomed Europe GmbH, Germany)
"The Challenge of Pump Miniaturization"
7:30 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
New Approaches in Mechanical Support
New technologies have arrived to the research and development phase and their merit and potential will be discussed. Alternative modes of mechanical support like the total artificial heart has reached the first clinical applications and can change the field in the coming years.
Discussion Leaders: Kurt Dasse (University of Louisville School of Medicine, USA) and Stephan Schueler (Freeman Hospital, United Kingdom)
9:00 am - 9:15 am
Carl Botterbusch (CorWave SA, France)
"Corwave Neptune: The Wave Membrane Pump"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
James Long (INTEGRIS Advanced Cardiac Care, USA)
"Miniature Endovascular LA Assist Device for Diastolic Dysfunction: Not Your Average VAD"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Roland Graefe (ReinVAD GmbH, Germany)
"The ReinVAD LVAD: Smart Technology to Enhance Long-Term Circulatory Support Therapy"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Daniel Timms (BiVACOR Inc., USA)
"Advancing the Physiological Interaction of Total Artificial Hearts and the Cardiovascular System"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
Jeffrey Gohean (Windmill Cardiovascular Systems, USA)
"The Torvad: Physiological Hemodynamics and Autoadaptive Support"
11:05 am - 11:10 am
Discussion
11:10 am - 11:25 am
Arnt Fiane (University of Oslo, Norway)
"PulseVAD for HfpEF"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Stuart McConchie (Calon Cardio-Technology Ltd, United Kingdom)
"The Calon Cardio-Technology LVAD"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Valluan Jeevanandam (University of Chicago Medicine, USA)
"iVAS: A Versatile Device for Patients Without LVAD Options"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Chen Chen (CH Biomedical, Inc., China)
"Design and Characteristics of the CH-VAD"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
The Strategy Towards the Ambulatory Patient
This session will summarize the steps to be taken to reach out to the ambulatory heart failure patient. The plan will be constructed from a research, business, clinical and management perspective.
Discussion Leader: Francis Pagani (University of Michigan, USA)
6:00 pm - 6:20 pm
Tim Baldwin (U.S. Food and Drug Administration, USA)
"The Regulatory Restrictions to Obtain Support for the Ambulatory Patient"
6:20 pm - 6:35 pm
Discussion
6:35 pm - 6:55 pm
Garrick Stewart (Brigham and Women's Hospital, USA)
"Lessons from Revive It and Revival"
6:55 pm - 7:10 pm
Discussion
7:10 pm - 7:30 pm
James Antaki (Cornell University, USA)
"The Roadmap Towards the Ambulatory Patient"
7:30 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure