Sunday, June 15
7:00 - 9:30 PM: CELL SIGNALING EVENTS AFFECTING VASCULAR TONE AND GROWTH
Session Leader: Masashi Yanagisawa
- Masashi Yanagisawa - The Role of Endothelins and Receptors in Vascular Homeostasis: Genetic Analysis in Mice
- Jonathan Stamler - Hemoglobin: A Microcosm of NO signaling in the Vasculature
- Thomas Sato - Roles of TIE Receptor Tyrosine Kinases in Blood Vessel Formation
Monday, June 16
9:00 - 12:30PM: GENETIC APPROACHES TO THE STUDY OF ATHEROSCLEROSIS
Session Leader: Eric Lander
- Jan Breslow - Genetic Modifiers of Atherosclerosis in the ApoE Knockout Mouse
- Rick Lifton - Molecular Genetics of Hypertension and its Consequences
- Jonathan Cohen - Genetic Determinants of Plasma HDL-Cholesterol Levels
4:30 - 5:30PM: Workshop: SCIENTIFIC OPPORTUNITIES IN CARDIOVASCULAR RESEARCH
Jan Breslow
7:30 - 10:00PM: EXPERIMENTAL MODELS AND METHODOLOGIES TO STUDY ATHEROSCLEROTIC LESIONS AND PLAQUE RUPTURE
Session Leader: Russell Ross
- Russell Ross -Studies of Chimeric ApoE-/- Mice
- Jake Lusis - Mouse Models: Secretory Phospholipase A2, Lipid Oxidation, and Atherosclerosis
- Arthur Beaudet - Genetic Analysis of Leukocyte and Endothelial Cell Adhesion Molecules in Atherosclerosis
- Andras Nagy - ES Cell-Mediated Genetic Approaches for Studying Vessel Development
- David Stern - Accelerated Atherosclerosis and Diabetes: Role of RAGE
Tuesday, June 17
9:00 - 12:30PM: USE OF GENE TRANSFER TECHNIQUES IN ANGIOGENESIS AND ATHEROGENESIS
Session Leader: Jeff Leiden
- Jeff Leiden - Adenovirus-Mediated Gene Transfer to Understand and Treat Vascular Proliferative Disorders
- Elizabeth Nabel - Cyclin-Dependent Kinase Inhibitors and Vascular Disease
- Jeffrey Isner - VEGF Gene Transfer Offers Clues to Endogenous Mechanisms
- Victor Dzau - E2F Transcriptional Factor Decoy for Genetic Engineering of Vascular Graft
4:30-5:30PM: Workshop
CLINICAL APPROACH TO CORONARY ARTERY DISEASE: BENCH TO BEDSIDE
Victor Dzau, Elizabeth Nabel, Jeff Leiden, Antonio Gotto
4:30-6:30: Poster Session 1
7:30 - 10:00PM: ROLE OF INFLAMMATORY CELLS IN LESION PROGRESSION AND REGRESSION
Session Leader: Edgar Haber
- Edgar Haber - Role of MHC I and MHC II in Transplant Arteriosclerosis
- Peter Libby - CD40L: Not Just Another Cytokine
- Joe Witztum - Humoral Response to Oxidation-Dependent Epitopes and Potential Roles in Atherosclerosis
- Goran Hansson - Cell-Mediated Immunity and the Regulation of Inflammation
Wednesday, June 18
9:00 - 12:30PM: LIPOPROTEIN BIOLOGY AND ATHEROSCLEROSIS
Session Leader: Helen Hobbs
- Ira Tabas - Sphingomyelinase and Atherogenesis
- Jay Heinecke - Pathways for Oxidative Damage in Atherosclerosis
- Nobuyo Maeda - Human Apolipoprotein E Alleles in Mice and Atherosclerosis
- *MacRae Linton - Macrophage Apolipoprotein E in Atherosclerosis
- *Maria Febbraio - The Role of CD36 in Atherosclerotic Foam Cell Development
- *Attilio Rigotti - Recent Studies of SR-BI function in vivo
4:30-5:30PM: Workshop
ANALYSIS OF LESIONS IN MAN AND MOUSE
Alan Daugherty, Sotirios Tsimikas, MacRae Linton
7:30 - 10:00 PM: MATRIX AND VASCULAR REMODELING
Session Leader: Richard Hynes
- Richard Hynes - Integrins in Vascular Form and Function
- Jack Lawler - Thrombospondins in the Vessel Wall
- Denisa Wagner - Leukocyte Adhesion Receptors in Atherosclerosis and Obesity
- Bjorn Olsen - Venous Malformations - Genetics Abnormalities in Vascular Morphogenesis
Thursday, June 19
9:00 - 12:30PM: MOLECULAR LINKS BETWEEN THROMBOSIS AND ATHEROSCLEROSIS
Session Leader: David Loskutoff
- David Loskutoff - Introduction and Discussion of Murine Models of Thrombotic Disease
- Dan Lawrence - A Molecular Switch Regulating Smooth Muscle Cell Migration by a Single Conformational Change
- Peter Carmeliet - Role of Urokinase in Activation of Matrix Metalloproteinase During Aneurysm Formation in Atherosclerotic Mice
- Jay Degen - Role of Plasminogen and Fibrinogen in Atherosclerosis
- Fahumiya Samad - Adipose Tissue Expression of Hemostatic Genes: Potential Contributor to Cardiovascular Complications in Obesity?
4:30-6:30: Poster Session 2
8:00-9:00 PM: KEY NOTE SPEECH
Session Leader: David Hajjar
- Oliver Smithies - Gene Targeting in the Study of Genetic Diseases
|
