| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Etiology of Atherosclerosis: Lipoproteins and Other Risk Factors |
| Session Chair: Linda Curtiss, Scripps Research Institute |
| James Scott, Imperial College of Medicine, London, UK
Lipoprotein regulation in the metabolic syndrome |
| Dan Rader, University of Pennsylvania
Lipases in the regulation of HDL metabolism |
| Anne Soutar, Imperial College of Medicine
London, UK. Partners in LDL receptor ligation |
| Bernadette Holdener, SUNY - Stony Brook
Regulation of LDL Receptor Family Expression by a novel chaperone |
| 9:30 | Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am | Group Photo |
| 9:00 am - 12:30 pm | Insulin Resistance and the Metabolic Syndrome |
| Session Chair: Peter Davies, University of Pennsylvania |
| Luciano Rossetti, Albert Einstein College of Medicine
Novel Mechanisms of Insulin Resistance |
| Peter McNamara, Phenomix Corporation
A pervasive role of the circadian clock in modulation of glucose and lipid homeostasis |
| Clay Semenkovich, Washington University
Fatty acid metabolism and vascular dysfunction |
| Sonia Najjar, Medical College of Ohio
CEACAM, a protein at the crossroads of insulin clearance and fat metabolism |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Obesity and the Metabolic Syndrome |
| Session Chair: Alan Attie, University of Wisconsin |
| Karen Reue, UCLA
Lipin: a new player in adipose tissue function |
| James Ntambi, University of Wisconsin - Madison
The role of stearoyl CoA desaturase in body weight regulation |
| Steve O'Rahilly, University of Cambridge
The human genetics of obesity |
| Tomomi Ide, University of Pennsylvania
Natural ligands for PPARs |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Angiogenesis and Vascular Regeneration |
| Session Chair: Betsy Nabel, NHLBI |
| George Yancopoulos, Regeneron
Angiogenesis and inflammation |
| Peter Carmeliet, University of Leuven
VEGF and new vessel formation |
| David Cheresh, Scripps Research Institute, UCSD
Integrin delivery and modulation |
| Des Fitzgerald Royal College of Surgeons, Ireland
The proteomics of platelet activation |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Oxidation and Inflammation |
| Session Chair: Joachim Herz, University of Texas SW |
| Joe Witztum, University of California, San Diego
CRP and lipoproteins |
| Colin Funk, University of Pennsylvania
The spectrum of lipoxygenases in atherogenesis |
| Phillipe Boucher, University of Texas SW
LRP and PDGF signaling a pathway to atherosclerosis |
| Bart van Vlijmen, Leiden University
A role for LRP in atherosclerosis independent of plasma cholesterol |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | The Vascular Biology of the Metabolic Syndrome |
| Session Chair: Bill Sessa, Yale University |
| Jonathan Stamler, Duke University
Structural considerations of NO biology |
| Guy Zimmerman, University of Utah
Signaling to translational checkpoints in vascular and inflammatory cells |
| DG Hardie, University of Dundee
AMP activated protein kinases: a cellular energy sensor and a key player in the metabolic syndrome. |
| Brant Weinstein, NICHD
Vascular developments in zebrafish. |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Genomics and Proteomics of the Metabolic Syndrome |
| Session Chair: Jake Lusis, UCLA |
| Jake Lusis, UCLA
The genetics of a very complex disease. |
| John Hogenesch, Genomics Inst of the Novartis Foundation
Bioinformatic approaches to the metabolic syndrome |
| Vamsi Mootha, Whitehead Institute / MIT Center for Genome Research
Mitochondrial contribution to human disease: an integrative genomics approach |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Lipoprotein Transport |
| Session Chair: Garret FitzGerald, University of Pennsylvania |
| Alan Tall, Columbia University
Regulation of ABCAI. |
| Helen Hobbs University of Texas SW
Genetic disorders of lipoprotein transport. |
| Amy Davidson, Baylor College of Medicine
The structural biology of ABC transporters. |
| Stephen Sturley, Columbia University
Novel ABC Transporters |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 6:00 pm | Dinner |
| 8:00 pm - 9:30 pm | Keynote Lecture |
| 8:00 pm - 9:30 pm | Oliver Smithies, University of North Carolina
Genetic models of vascular disease. |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
