Session I |
Sunday June 21, 1998 |
7:00 PM |
Periplasmic protein folding |
Discussion leader: Carol Gross (UC, San Francisco, CA, USA)
- Dominique Missiakas (CNRS, Marseilles, France):
Protein folding in the periplasm
- Jon Beckwith (Harvard University, Cambridge, USA):
Thioredoxin can efficiently promote disulfide bond formation when exported to the periplasm
- Jean-Michel Betton (Institut Pasteur, Paris, France):
Misfolding of the maltose-binding protein in the periplasm of Escherichia coli
- Satish Raina (University of Geneva, Switzerland):
A novel heat shock gene in Escherichia coli, ppiD, which encodes a peptidyl-prolyl isomerase and is required for the folding of outer membrane proteins
- Hajime Tokuda (University of Tokyo, Japan):
Sorting and the outer membrane localization of lipoproteins
Session II |
Monday June 22, 1998 |
9:00 AM |
Protein Traffic I |
Discussion leader : William Wickner (Dartmouth College, Hanover, NH, USA):
- Tom Rapoport (Harvard University, Boston, MA, USA):
Posttranslational protein transport across the ER membrane
- Don Oliver (Wesleyan University, Middletown, CT, USA):
Role of membrane dynamics of SecA ATPase in bacterial protein translocation
- Koreaki Ito (University of Kyoto, Japan):
Specific interaction between SecY and SecA during translocation of presecretory proteins
- Matti Sarvas (National Public Health Institute, Helsinki, Finland):
Ecs, an ABC transporter of Bacillis subtilis; a dual signal transduction function in coordinated expression of secreted proteins and regulation of their secretion
- Harris Bernstein (NIH, Bethesda, USA):
The SRP targeting pathway in E. coli.
- Tracy Palmer (John Innes Center, Norwich, UK):
A Sec-independent protein translocase for the export of redox proteins in Escherichia coli
Session III |
Monday June 22, 1998 |
7:00 PM |
Signal transduction |
Discussion leader: Michael Manson (Texas A&M, College Station, TX, USA)
- Beth Lazazzera (MIT, Cambridge, MA, USA)
Cell-cell signaling in B. subtilis
- Gary Dunny (University of Minnesota, Minneapolis, USA)
Intracellular and extracellular regulation of pheromone-inducible surface proteins in enterococci
- Thomas J. Silhavy (Princeton Univ., Princeton, NJ, USA)
Parallel pathways perceive periplasmic problems
- Carey Waldurger (Columbia University, New York, USA)
Subdomain structure of the bacterial PhoQ histidine kinase
- Orna Amster-Choder (Hebrew University Medical School, Jerusalem, Israel)
Stimulus-induced conformational change in the sensor of the bgl system: alteration between S-P and S-S bonds
Session IV |
Tuesday June 23, 1998 |
9:00 AM |
Bacterial Cell Surface Polymers |
Discussion leader: Joachim Holtje (University of Tübingen, Germany)
- Christine Jacobs (Stanford University, CA, USA)
Peptidoglycan metabolism and ß-lactamase induction: two systems intimately linked
- Girbe Buist (University of Groningen, The Netherlands)
The N-acetylmuraminidase of Lactococcus lactis binds to the cell wall by means of repeated motifs located in the C-terminal domain
- Clifton Barry (Rocky Mountain Laboratories, Hamilton, USA):
Biosynthesis and function of mycolic acids in Mycobacterium tuberculosis: novel drug
targets?
- Mamadou Daffe (CNRS, Toulouse, France):
Structure and possible functions of the outermost capsular constituents of Mycobacterium tuberculosisand other mycobacteria
- Chris Raetz (Duke University, Durham, NC, USA):
Assembly and secretion of lipopolysaccharide.
- Chris Whitfield (University of Guelph, Canada):
Two distinct translocation pathways for ß-chain lipooligosaccharide variation in Neisseria gonorrhoeae
Session V |
Tuesday June 23, 1998 |
7:00 PM |
Structure of Membrane Proteins |
Discussion leader: Don Engelman (Yale Univ. New Haven, CT, USA)
- Jurg Rosenbusch (University of Basel, Switzerland)
Structure determination of membrane proteins: bacteriorhodopsin
- Phil Klebba (University of Oklahoma, Norman, OK, USA)
Mechanisms of ligand transport through gated porins
- Hagan Bayley (Texas A & M, College Station, TX, USA)
Membrane insertion and structure of staphylococcal alpha toxin
- George Robillard (University of Groningen, The Netherlands)
5-Å projected structure of the transmembrane domain of the enzyme II mannitol transporter by cryoelectron crystallography
Sesssion VI |
Wednesday June 24, 1998 |
9:00 AM |
Transport |
Discussion leader: Ian R. Booth (Univ. Aberdeen, Aberdeen, Scotland)
- Milton Saier (Univ. Calif. San Diego, CA, USA)
Molecular archeological studies leading to the classification of transport
systems in bacteria, archaea, and eukarya
- Beth Traxler (Univ. of Washington, Seattle, WA, USA)
Maltose transport in E. coli
- Volkmar Braun (University of Tübingen, Germany)
Insertion of a periplasmic binding protein into an integral cytoplasmic membrane transport protein
- Bert Poolman (University of Groningen, The Netherlands)
Detergent-mediated reconstitution of membrane proteins
- Paul Blount (Univ. of Texas, Dallas, TX, USA)
Mechanosensitive channels in bacteria, from genes to physiology
- Hiroshi Nikaido (University of California, CA, USA)
AcrA of E. coli is a highly asymmetric protein capable of spanning the periplasm
Session VII |
Wednesday June 24, 1998 |
7:00 PM |
Cell Division |
Discussion leader: Joe Lutkenhaus (University of Kansas, KS, USA)
- Piet de Boer (Case Western Reserve University, Cleveland, OH,USA):
Positioning of the division septum in E.coli.
- Andrew Wright (Tufts University, Boston, MA,USA):
Chromosome and low copy plasmid segregation in E. coli: Visual evidence for
distinct mechanisms
- Jim Gober (University of California, Los Angeles, CA, USA):
Chromosome Partitioning and the Regulation of Cell Division in Caulobacter
- Alan Grossman (MIT, Cambridge, MA, USA)
Chromosome dynamics in B. subtilis
Session VIII |
Thursday June 25, |
9:00 AM |
Protein Traffic II |
Discussion leader: Tony Pugsley (Institut Pasteur, Paris, France):
- Cécile Wandersman (Institut Pasteur, Paris):
Hemophore HasA secretion by an ATP binding cassette exporter: a new type of hemophore dependent heme acquisition system in Gram negative bacteria.
- Vassilis Koronakis (Cambridge University, UK)
Type I export of hemolysis toxin: dynamic interactions of the outer membrane porin-like TolC with the energized inner membrane complex
- Dan Wall (Stanford University, Stanford, CA, USA):
Tgl Contact Stimulation and Type IV pili in Myxococcus xanthus.
- David Thanassi (Washington University, St. Louis, MO, USA)
Role of PapC usher in pilus biogenesis across the outer membrane
- Olaf Schneewind (University of California, Los Angeles, CA, USA):
A new look at the type III protein secretion system in Yersinia
- Shi-Ichi Aizawa (Tokyo University, Tokyo, Japan):
Flagellar assembly
Session IX |
Thursday June 25, 1998 |
7:00 PM |
Bacterial Contact with Eukaryotes |
Discussion leader: Howie Shuman (Columbia University, New York, USA)
- Ulla Bonas (CNRS, France & Institute of Genetics & Martin Luther University, Halle, Germany)
Protein communication between the plant pathogen Xanthomonas and its host
- Kristen Le Vier (MIT, Cambridge, MA, USA)
Analysis of the Rhizobium meliloti BacA protein: implications for host-microbe interactions
- Tina Guina (University of Washington, Seattle, USA)
A PhoP-activated gene is essential for antimicrobial peptide resistance and lipid A modification
- Ralph Isberg (Tufts University, Boston, MA, USA)
Targetting the Legionella pneumophila within phagocytic cells
- Vincent Fischetti (Rockefeller Univ. New York, NY, USA)
Signal transduction in human pharyngeal cells induced by group A streptococci