| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:35 pm | Welcome / Introductory Comments by GRC Site Staff and the Chairs |
| 7:35 pm - 9:30 pm | CELL ENVELOPE STRESS AND PERIPLASM |
| Discussion Leader: Thomas Silhavy (Princeton University) |
| 7:35 pm - 7:45 pm | Discussion Leader's Remarks |
| 7:45 pm - 8:10 pm | Robert Sauer (MIT)
"The Envelope-Stress Response: Switch Design and Function" |
| 8:10 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:45 pm | Gisela Storz (National Institutes of Health)
"Linking Stress Responses with Small Membrane Proteins" |
| 8:45 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Anthanasios Typos (UCSF)
"High throughput interaction analyses provide mechanistic insights into envelope function in E. coli" |
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PROTEIN LOCALIZATION AND SECRETION |
| Discussion Leader: Françoise Jacob-Dubuisson (Institut Pasteur de Lille) |
| 9:00 am - 9:10 am | Discussion Leader's Remarks |
| 9:10 am - 9:35 am | Richard Losick (Harvard University)
"Life and Death of a Microbial Community" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Miriam Braunstein (University of North Carolina)
"The SecA2 Accessory Sec System of Mycobacteria" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break / Group Photo |
| 10:45 am - 11:10 am | Arnold Driessen (University of Groningen)
"Mechanism of bacterial protein secretion: a single molecule study" |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:45 am | Lotte Søgaard-Andersen (Max Plank Institute)
"Regulation of Cell Polarity in a Bacterium by a Member of the Ras Superfamily of Small GTPases" |
| 11:45 am - 11:55 am | Discussion |
| 11:55 am - 12:20 pm | Wim Hol (University of Washington)
"Structural Biology of the Type 2 Secretion System" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PEPTIDOGLYCAN |
| Discussion Leader: Jeff Errington (University of Newcastle) |
| 7:30 pm - 7:40 pm | Discussion Leader's Remarks |
| 7:40 pm - 8:05 pm | Waldemar Vollmer (University of Newcastle)
"Peptidoglycan Synthesis: from Enzyme Activities to Morphogenesis" |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Eefjan Breukink (Utrecht University)
"FtsW is a Transporter of Bactoprenol-linked Peptidoglycan Subunits" |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:15 pm | Thomas Bernhardt (Harvard Medical School)
"Cytokinetic ring-activated cell wall hydrolysis" |
| 9:15 pm - 9:25 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | OUTER MEMBRANE |
| Discussion Leader: Natividad Ruiz (Princeton University) |
| 9:00 am - 9:10 am | Discussion Leader's Remarks |
| 9:10 am - 9:35 am | Mamadou Daffé (Institute of Pharmacology and Structural Biology)
"The Paradoxal Outer Membrane of Typical Gram-positive Bacteria" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Alessandra Polissi (University of Milano)
"The Lpt Machinery for LPS Transport to the Cell Surface: Understanding the Role of LptA and LptC" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:40 am - 11:05 am | Thomas Silhavy (Princeton University)
"Genetic Analysis of Outer Membrane Biogenesis" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:40 am | Jörg Kleinschmidt (Universität Konstanz)
"Effects of Periplasmic Folding Factors on the Insertion and Folding of Outer Membrane Proteins into Lipid Membranes" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:05 pm | Christine Hagan (Harvard University)
"Reconstitution of Outer Membrane Protein Assembly from Purified Components" |
| 12:05 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Aniek Van Der Woude (Vu University)
"An unexpected link between PE_PGRS secretion and lipooligosaccharide biosynthesis in Mycobacterium marinum" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SIGNAL SENSING AND TRANSDUCTION |
| Discussion Leader: Richard Losick (Harvard University) |
| 7:30 pm - 7:40 pm | Discussion Leader's Remarks |
| 7:40 pm - 8:05 pm | Roberto Kolter (Harvard Medical School)
"Control of Extracellular Matrix Synthesis in Bacillus subtilis" |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Caroline Harwood (University of Washington)
"How the Intracellular Messenger cyclic di-GMP Controls Biofilms" |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:15 pm | Sean Crosson (University of Chicago)
"Remodeling the Cell Surface via an Integrated Two-Component/ECF Sigma Pathway" |
| 9:15 pm - 9:25 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CELL MORPHOGENESIS |
| Discussion Leader: Yves Brun (Indiana University) |
| 9:00 am - 9:10 am | Discussion Leader's Remarks |
| 9:10 am - 9:35 am | Kit Pogliano and Pieter Dorrestein (University of California, San Diego)
"Remodeling cellular membranes during Bacillus subtilis development" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Joshua Shaevitz (Princeton University)
"Cell Wall Mechanics and Dynamics of Rod-Shaped Bacteria" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:40 am - 11:05 am | Jeff Errington (University of Newcastle)
"Requirements for Genesis and Survival of Bacillus subtilis L-forms" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:40 am | Joe Lutkenhaus (University of Kansas Medical Center)
"Spatial regulation of division in E. coli" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:05 pm | Doug Weibel (University of Wisconsin-Madison)
"Formation of lipid microdomains in bacterial membranes localizes proteins" |
| 12:05 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Catherine Paradis-Bleau (Harvard Medical School)
"Redundant lipoprotein-PBP complexes are essential for E. coli cell wall assembly" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | MICROBIAL COMMUNITIES AND ANTIBIOTICS |
| Discussion Leader: Roberto Kolter (Harvard Medical School) |
| 7:30 pm - 7:40 pm | Discussion Leader's Remarks |
| 7:40 pm - 8:05 pm | Jo Handelsman (Yale University)
"Multispecies Microbial Interactions in the Caterpillar Gut" |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Urs Jenal (University of Basel)
"Regulation of Caulobacter Cell Cycle and Development by Cyclic di-GMP" |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:15 pm | Nathalie Balaban (The Hebrew University of Jerusalem)
"Regulation of Phenotypic Variability" |
| 9:15 pm - 9:25 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | TRANSPORT |
| Discussion Leader: Arnold Driessen (University of Groningen) |
| 9:00 am - 9:10 am | Discussion Leader's Remarks |
| 9:10 am - 9:35 am | Samantha Miller (University of Aberdeen)
"Bacterial Mechanosensitive Channels: Structure and Mechanism" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Isabelle Schalk (Institut Gilbert-Laustriat)
"Transport of Metals by Siderophores in Pseudomonas aeruginosa" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am | Coffee Break |
| 10:40 am - 11:05 am | Kaspar Locher (Eidgenössische Technische Hochschule Zürich)
"Structure and Mechanism of Bacterial ABC Transporters" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:40 am | Bert van den Berg (University of Massachusetts)
"Cleaning up the mess: uptake of hydrophobic compounds across the outer membrane" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:05 pm | Michael Mourez (University of Montreal)
"Physical Organization of Bacterial Communities by Self-Associating Molecules" |
| 12:05 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Jason Wallace (Yale University)
"A Large, Noncoding RNA Associated with the Membranes of Extremophilic Bacteria" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | EXTRACELLULAR MATRICES, ORGANELLES AND SURFACE POLYMERS |
| Discussion Leader: Lotte Søgaard-Andersen (Max Plank Institute at Marburg) |
| 7:30 pm - 7:40 pm | Discussion Leader's Remarks |
| 7:40 pm - 8:05 pm | Yves Brun (Indiana University)
"Regulation and Biophysics of Caulobacter Surface Adhesion" |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Michael Koomey (University of Oslo)
"Both sides now - extracellular and intracellular roles for unique post-translational modifications of membrane proteins" |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:15 pm | Sonja-Verena Albers (Max Plank Institute at Marburg)
"Diversity of Archaeal Type IV pili" |
| 9:15 pm - 9:25 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |