Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Bacterial Communities and Motility |
| Discussion Leader: Eric Klein (Rutgers University-Camden, USA) |
7:40 pm - 7:45 pm | Introduction by Discussion Leader |
7:45 pm - 8:05 pm | Judith Armitage (University of Oxford, United Kingdom) "Flagella Motor Re-Engineering in Response to Environmental Change" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:35 pm | Ned Wingreen (Princeton University, USA) "Building a Biofilm the Vibrio cholerae Way" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:05 pm | Lotte Sogaard-Andersen (Max Planck Institute for Terrestrial Microbiology, Germany) "Assembly, Architecture, Function and Regulation of Type IV Pili" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Daniel Lopez (Spanish National Centre for Biotechnology, Spain) "Cell Fate Decision Decides Acute and Chronic Infection Cell Types in Staphylococcus aureus" |
9:25 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cell Division and Morphogenesis |
| Discussion Leader: Rut Carballido-Lopez (Institut National de la Recherche Agronomique (INRA), France) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Jan Lowe (MRC Laboratory of Molecular Biology, United Kingdom) "Structure of Actin-Like Magnetosome Protein MamK in Monomeric and Filamentous Forms" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Marisela Velez (Instituto de Catálisis y Petroleoquímica, Spanish National Research Council, Spain) "A Surface to Twist the FtsZ Filament: A Good Strategy to Generate Force" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Christophe Grangeasse (CNRS / Université de Lyon, France) "Cell Division of Streptococcus pneumoniae: How the Phosphoprotein MapZ Positions at Mid-Cell" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Christine Jacobs-Wagner (Yale University, USA) "How Do Lyme Disease Borrelia burgdorferi and Other Spirochetes Grow and Divide?" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Thomas Bartlett (Princeton University, USA) "Vibrio cholerae Cell Curvature Is Determined by a Quorum-Regulated Periplasmic Polymer" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Leigh Harris (Stanford University, USA) "Relative Rates of Surface and Volume Synthesis Set Bacterial Cell Size" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Antibiotics - What Works and What's Missing |
| Discussion Leader: Hans-Georg Sahl (University of Bonn, Germany) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 7:55 pm | Hans-Georg Sahl (University of Bonn, Germany) "Cell Envelope Biosynthesis Pathways as Antibiotic Targets" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Heike Broetz-Oesterhelt (Institute for Microbiology and Infection Medicine, University of Tübingen, Germany) "Bacterial Clp Proteases as Novel Targets in Antibacterial Drug Discovery" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Steven Projan (MedImmune, USA) "A Bi-Specific Monoclonal Antibody Targeting Two Surface Features of Pseudomonas aeruginosa Has Superior Activity in Animal Models of Infection" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Cara Boutte (Harvard T.H. Chan School of Public Health, USA) "A Cytoplasmic Peptidoglycan Amidase Homologue Controls Mycobacterial Cell Wall Synthesis" |
9:25 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Membrane Dynamics |
| Discussion Leader: Stephen Trent (University of Georgia, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Julie Biteen (University of Michigan, USA) "Imaging Outer-Membrane Proteins and Membrane-Bound Transcription Regulators on the Nanometer Scale with Single-Molecule Tracking in Live Cells" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Dan Wall (University of Wyoming, USA) "Outer Membrane Fusion and Exchange in Myxobacteria" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Daniel Kahne (Harvard University, USA) "From Penicillin to the PEZ Machine" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Kerwyn Huang (Stanford University, USA) "Taking Bacteria Apart and Putting Them Back Together Again" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Kerrie May (Princeton University, USA) "E. coli Phospholipase PldA: A Sentinel for Outer Membrane Lipid Homeostasis" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Angela Schlegel (Washington University in St. Louis, USA) "A Fluorescence-Based Genetically-Encoded Lateral Membrane Tension Biosensor" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Surface Polymers |
| Discussion Leader: Lori Burrows (McMaster University, Canada) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 7:55 pm | Sonja-Verena Albers (University of Freiburg, Germany) "Assembly of the Motor Complex of the Archaellum, the Archaeal Motility Structure" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Alice Chateau (University of Chicago, USA) "Assembly and Function of the Bacillus anthracis S-Layer" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Katharina Ribbeck (Massachusetts Institute of Technology, USA) "Probing Microbial Interactions with the Mucus Barrier" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Morgan Beeby (Imperial College London, United Kingdom) "Diverse High-Torque Bacterial Flagellar Motors Assemble Wider Stator Rings Using a Conserved Protein Scaffold" |
9:25 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Peptidoglycan Metabolism |
| Discussion Leader: Waldemar Vollmer (Newcastle University, United Kingdom) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Yves Brun (Indiana University, USA) "Mechanism and Evolution of Bacterial Morphogenesis" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Elizabeth Sockett (University of Nottingham, United Kingdom) "Murochronology of Self and Prey Wall Modifications by Bdellovibrio" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Jonathan Dworkin (Columbia University, USA) "Regulatory Crosstalk Drives Phenotypic Variability in Antibiotic Sensitivity" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Kevin Young (University of Arkansas for Medical Sciences, USA) "Synthesis of Peptidoglycan and Extracellular Polysaccharides: Complications of Partial Pathways and Common Precursors" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Raquel Pereira (Instituto de Tecnologia Química e Biológia (ITQB-UNL), Universidade Nova de Lisboa, Portugal) "FtsZ-Dependent Morphogenesis of Elongated Cells in the Cocci Bacteria Staphylococcus aureus" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Sven van Teeffelen (Institut Pasteur, France) "Constraints on the Diffusive Dynamics of the Cell-Wall Insertion Machinery" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Stress Responses and Signaling |
| Discussion Leader: Carol Gross (University of California, San Francisco, USA) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 7:55 pm | Karina Xavier (Instituto Gulbenkian de Ciência, Calouste Gulbenkian Foundation, Portugal) "Manipulation of the Quorum Sensing Signal AI-2 Affects the Antibiotic-Treated Gut Microbiota" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Cynthia Whitchurch (ithree Institute, University of Technology Sydney, Australia) "Production of Bacterial Public Goods via Explosive Cell Lysis" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Samuel Miller (University of Washington, USA) "Glycerolphospholipid Transport and Regulation in the Outer Membrane" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | George Liechti (Uniformed Services University of the Health Sciences, USA) "Pathogenic Chlamydia Lack a Classical Sacculus but Synthesize a Narrow, Midcell Peptidoglycan Ring, Regulated by MreB, for Cell Division" |
9:25 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Protein Transport and Secretion |
| Discussion Leader: Maria Sandkvist (University of Michigan Medical School, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Jorge Galan (Yale School of Medicine, USA) "Type III Protein Secretion Machines: New Insights" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Melanie Blokesch (École Polytechnique Fédérale de Lausanne, Switzerland) "The Role of the Type VI Secretion System in Vibrio cholerae's Environmental Lifestyle" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Kelly Hughes (University of Utah, USA) "Hitting a Wall as a Length Control Mechanism in Flagellar Rod Assembly" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:50 am | Jean Francois Collet (WELBIO / Université Catholique de Louvain, Belgium) "Revisiting Lipoprotein Sorting in Gram-Negative Bacteria" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Aaron Wexler (Yale University, USA) "Symbiosis Through Warfare: Contact-Dependent Dynamics in the Human Gut Microbiome" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Courtney Ellison (Indiana University, USA) "Role of Tad Pili and Their Retraction in Surface-Contact Stimulation of Holdfast Deployment in Caulobacter crescentus" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Bacterial Interactions with Hosts and Surfaces |
| Discussion Leader: Kimberly Kline (Nanyang Technological University, Singapore) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:00 pm | Karine Gibbs (Harvard University, USA) "Self Versus Nonself Recognition: Exploring the Interplay of Self-Identifiers and the Bacterial Cell Envelope" |
8:00 pm - 8:05 pm | Discussion |
8:05 pm - 8:25 pm | Ivo Boneca (Institut Pasteur, France) "The Peptidoglycan as a Signaling Molecule in the Host" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Wendy Thomas (University of Washington, USA) "How Bugs in Bodily Fluids Catch Hold of Cells and Surfaces" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Nina Salama (Fred Hutchinson Cancer Research Center, USA) "Learning to Twist, Helicobacter-Style" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |