SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Defining Mammalian Barrier Function |
| Discussion Leader: Audra Stinchcomb (University of Maryland School of Pharmacy) |
7:40 pm - 8:05 pm | Steven Hoath (University of Cincinnati)
"Parallel development of mammalian barriers during gestation" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Peter Elias (University of California, San Francisco)
"Stratum corneum defensive functions - a Buddhist view of the interconnectedness of protective functions" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Matthias Schaefer (ETH Zurich)
"Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | New Approaches for Investigating Barrier Function |
9:00 am - 9:15 am | Discussion Leader: Joachim Fluhr (Charite - Universitatsmedizin Berlin)
"Introduction" |
9:15 am - 9:45 am | Konrad Sandhoff (University of Bonn, LIMES Institut)
"Ceramide metabolism: key to skin barrier function" |
9:45 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Group Photo / Coffee Break |
10:30 am - 11:00 am | Roger Wepf (Electron Microscopy ETH Zurich (EMEZ)) |
11:00 am - 11:15 am | Discussion |
11:15 am - 11:45 am | Richard Mendelsohn (Rutgers University)
"Novel infrared spectroscopy applications in skin science: lateral diffusion, spinodal decomposition, and wound healing" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | TBA (Hot Topic) |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | TBA (Hot Topic) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | In Vitro and Animal Models of Barrier Function |
| Discussion Leader: Dennis Roop (University of Colorado) |
7:30 pm - 8:10 pm | Gopinathan Menon (ASI Corporation)
"Models for skin barrier: beyond the mighty mouse" |
8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Spiros Getsios (Northwestern University, Feinberg School of Medicine)
"Building EPH-ective human epidermal models" |
9:10 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Atopic Dermatitis as a Model Barrier Disease |
9:00 am - 9:15 am | Discussion Leader: Matthias Schmuth (Innsbruck Medical University)
"Introduction" |
9:15 am - 9:45 am | Ehrhardt Proksch (University of Kiel)
"Influence of topical drug therapy on skin barrier, function, epidermal lipids, differentiation, and antimicrobial proteins in atopic dermatitis" |
9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:00 am | Joke Bouwstra (Leiden University)
"The role of lipids in the impaired skin barrier function of atopic eczema patients" |
11:00 am - 11:15 am | Discussion |
11:15 am - 11:45 am | Maria Morasso (Laboratory of Skin Biology, NIAMS, NIH)
"Periderm and embryonic development of the skin barrier" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | TBA (Hot Topic) |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | TBA (Hot Topic) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epidermal Barrier, Antimicrobial Peptides and the Microbiome |
7:30 pm - 7:45 pm | Discussion Leader: Lisa Beck (URMC Rochester)
"Introduction" |
7:45 pm - 8:25 pm | Richard Gallo (University of California, San Diego)
"The barrier as an element of innate immunity" |
8:25 pm - 8:40 pm | Discussion |
8:40 pm - 9:15 pm | Heidi Kong (Center for Cancer Research, NCI/NIH, Dermatology Branch)
"The cutaneous microbiome in health and disease" |
9:15 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Surmounting the Barrier to Administer Therapy |
9:00 am - 9:15 am | Discussion Leader: Philip Wertz (University of Iowa)
"Introduction" |
9:15 am - 9:45 am | Michael Roberts (Universities of South Australia & Queensland)
"Facilitating skin penetration by optimising drug-vehicle-skin interactions" |
9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:10 am | Richard Guy (University of Bath)
"Probing the skin-drug delivery platform interface" |
11:10 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Maureen Donovan (University of Iowa)
"The Olfactory Neuroepithelial Barrier as a Delivery Pathway to the CNS" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Hot Topic & Young Investigator Presentations |
| Discussion Leader: Reinhard Neubert (Martin Luther University Halle-Wittenberg, Institute of Pharmacy) |
| TBA (eight presentations of 10 minutes duration, and 5 minute discussion; to be selected from the abstracts received) |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Response to Barrier Perturbation: Epidermis and Beyond |
9:00 am - 9:15 am | Discussion Leader: Walter Holleran (University of California, San Francisco)
"Introduction" |
9:15 am - 9:45 am | Michael Rosenblum (University of California, San Francisco)
"Regulatory T cells in the skin" |
9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:00 am | Eung Ho Choi (Yonsei University Wonju College of Medicine)
"From skin barrier disruption to allergic inflammation" |
11:00 am - 11:15 am | Discussion |
11:15 am - 11:45 am | Yoshikazu Uchida (University of California, San Francisco)
"The role of ceramide and its metabolites in enhancing the epidermal antimicrobial barrier" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | TBA (Hot Topic) |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | TBA (Hot Topic) |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Debate Topic: "Nature vs. Nurture: Genetics are the Most Important Factor in Determining Barrier Function and Response" |
7:30 pm - 8:00 pm | Dennis Roop & Team (Pro) |
8:00 pm - 8:30 pm | Discussion |
8:30 pm - 9:00 pm | Nava Dayan & Team (Con) |
9:00 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |