Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Convergence of Biology and Technology
Discussion Leaders: Samir Mitragotri (Harvard University, USA) and Joachim Fluhr (Charite - Universitaetsmedizin Berlin, Germany)
7:40 pm - 8:20 pm
Mark Prausnitz (Georgia Institute of Technology, USA)
"Development of Microtechnologies for Medical Applications in the Skin"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Marjana Tomic-Canic (Miller School of Medicine, University of Miami, USA)
"Innovations in Wound Healing: Mechanisms, Diagnostics and New Treatments"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Atopic Dermatitis and Ichthyosis
Discussion Leaders: Dennis Roop (University of Colorado Anschutz Medical Campus, USA) and Eva Benfeldt (University of Copenhagen, Denmark)
9:00 am - 9:30 am
Theodora Mauro (University of California, San Francisco, USA)
"Atopic March: Role of the Epidermal Barrier Function"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Yasmine Belkaid (National Institute of Allergy and Infectious Diseases, NIH, USA)
"Microbiota Control of Infections "
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Group Photo / Coffee Break
11:00 am - 11:30 am
Pieter Dorrestein (University of California, San Diego, USA)
"Chemistry Associated with Skin Microbial Communities - Detection, Manipulation and Taking Control"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Thomas White (Stony Brook University, USA)
"Connexin Inhibition Alleviates Skin Disease in a Mouse Model of KID Syndrome"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizer: Eva Benfeldt (University of Copenhagen, Denmark)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
UV and the Barrier
Discussion Leaders: Walter Holleran (University of California, San Francisco, USA) and Neil Kitson (University of British Columbia, Canada)
7:30 pm - 8:00 pm
Martine Meinke (Charite - Universitaetsmedizin Berlin, Germany)
"Free Radical Formation and Radical Scavenging Activity of the Epidermal Barrier"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Mark Saltzman (Yale University, USA)
"Bioadhesive Nanoparticles for Topical Delivery to Skin"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Kenneth Tsai (Moffitt Cancer Center, USA)
"UV-Induced Somatic Mosaicism as a Marker of Skin Cancer Risk"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Wound Healing
Discussion Leader: Marjana Tomic-Canic (Miller School of Medicine, University of Miami, USA)
9:00 am - 9:30 am
Maria Morasso (National Institutes of Health, USA)
"The Molecular Anatomy of Oral and Cutaneous Wound Healing"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Kaushal Rege (Arizona State University, USA)
"Laser Activated Sealants for Skin Closure"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Kyeong Mi Kim (OliX Pharma, South Korea)
"siRNA Therapeutics Against Skin Diseases"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Westbrook Weaver (Tempo Therapeutics, Inc, USA)
"Improving Integration of Biomaterials During Dermal Regeneration"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Skin Hydration
Discussion Leaders: Richard Guy (University of Bath, United Kingdom) and Michael Roberts (University of Queensland / University of South Australia , Australia)
7:30 pm - 8:00 pm
Anthony Rawlings (AVR Consulting Ltd, United Kingdom)
"Dry Skin and the Molecular Basis of Stratum Corneum Maturation and Hydration"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Gerald Kasting (University of Cincinnati, USA)
"The Skin Barrier and an Emerging Technological Route of Analyte Access Through Eccrine Sweat"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Luis Monteiro Rodrigues (Universidade Lusofona, Portugal)
"Can Microcirculation Influence the Epidermal Barrier? (Using Mathematical Modeling to Simplify Complex Physiological Relationships In Vivo )"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Itch and Sensitive Skin
Discussion Leaders: Peter Elias (Veterans Administration Medical Center / University of California, San Francisco, USA) and Kenneth Feingold (Veterans Administration Medical Center / University of California, San Francisco, USA)
9:00 am - 9:30 am
Gil Yosipovitch (University of Miami , USA)
"Why Is My Dry Skin Itchy? Examining the Causes of Itch Associated with Skin Barrier Function and Structure"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Laurant Misery (University of Western Brittany, France)
"Sensitive Skin and Skin Barrier"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Marek Haftek (CNRS / University of Lyon, France)
"Changes of Cell Nanomechanical Properties According to the Stratum Corneum Depth and the Filaggrin Status in Atopic Dermatitis"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Sanja Kezic (Academic Medical Centre, The Netherlands)
"Corneocyte Surface Topography in Skin Inflammatory Diseases"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Selected Poster Presentations
Discussion Leaders: David Moore (GlaxoSmithKline, USA) and Marek Haftek (CNRS / University of Lyon, France)
7:30 pm - 7:40 pm
Arup Indra (Oregon Health and Science University, USA)
"Transcriptional Regulation of Epidermal Gene Network and Barrier Formation by Bcl11a/Ctip1"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Renata Martins Cardoso (Leiden University, The Netherlands)
"Impaired Body Lipid Metabolism in ApoE KO Mice Reduces Skin Barrier Function"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Yasuko Obata (Hoshi University, Japan)
"Effect of Ethanol and Isopropanol on the Lipid Lamellar Structure in Stratum Corneum Analyzed by Synchrotron X-Ray Diffraction"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Michael Recht (Palo Alto Research Center, Xerox Corporation, USA)
"Microjet Array for Needle-Free Delivery of Drug Particles"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Nathaniel Swofford (GlaxoSmithKline, USA)
"Characterization of Skin Binding via In Silico , In Vitro and In Vivo Models and Its Relationship with Pharmacodynamic and Pharmacokinetic Response"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Sophia Bergmann (University Medical Center Hamburg-Eppendorf, Germany)
"Biphasic Influence of Staphylococcus aureus on Epidermal Tight Junctions"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Petr Kasparek (Institute of Molecular Genetics of the ASCR, v. v. i., Czech Republic)
"Synergistic Effects of KLK5 and KLK7 Proteases Are Crucial for the Desquamation During Maturation of Epidermis"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Timothy Moore (Vanderbilt University, USA)
"Self-Assembly of Stratum Corneum Lipid Mixtures"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Tools
and Technologies
Discussion Leaders: Nicole Brogden (University of Iowa, USA) and Reinhard H. Neubert (Martin Luther University of Halle-Wittenberg, Germany)
9:00 am - 9:30 am
John Newsam (Tioga Research Inc., USA)
"Using Higher Throughput Screening in Topical Formulation Innovation"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
Dennis Roop (University of Colorado Anschutz Medical Campus, USA)
"Using Mouse Models to Understand How Epidermal Barrier Defects Lead to Predisposition to Develop Atopic Dermatitis"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
Pankaj Karande (Rensselaer Polytechnic Institute, USA)
"3D Printing of a Full-Thickness, Autologous and Vascularized Human Skin"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
Claus-Michael Lehr (Helmholtz Centre for Infection Research, Germany)
"Follicular Penetration of Nanoparticles as Platform for Non-Invasive Antigen Delivery to the Skin"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Follicular
Disorders
Discussion Leader: Gerald Kasting (University of Cincinnati, USA)
5:30 pm - 6:00 pm
Joke Bouwstra (Leiden Academic Centre for Drug Research (LACDR), Leiden University, The Netherlands)
"Hollow and Coated Microneedles for Dermal Vaccination"
6:00 pm - 6:10 pm
Discussion
6:10 pm - 6:40 pm
Dilip Paithankar (Sebacia, Inc., USA)
"Targeting Follicular Diseases with Plasmonic Resonant Particles and Optical Pulses"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
Juergen Lademann (Charite - Universitaetsmedizin Berlin, Germany)
"New Perspectives in Drug Delivery: Triggered Release of Drugs on Nanoparticles in Hair Follicles"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure