Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Cell Types of the Basal Ganglia
Discussion Leader: Rebekah Evans (Georgetown University, United States)
7:40 pm - 8:00 pm
Hongkui Zeng (Allen Institute for Brain Science, United States)
"Cell Type Organization in the Basal Ganglia"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Asa Wallen-Mackenzie (Uppsala University, Sweden)
"Heterogeneity of the Subthalamic Nucleus"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Fumino Fujiyama (Hokkaido University, Japan)
"Morphological Reevaluation of Basal Ganglia Network"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
Tianyi Mao (Vollum Institute/Oregon Health and Science University, United States)
"Cell Type-Specific Intracellular Signaling of Striatal Neurons Responding to Multiple Neuromodulators in vivo "
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Dopamine and Learning
Discussion Leader: Meaghan Creed (Washington University School of Medicine, United States)
9:00 am - 9:20 am
Erin Calipari (Vanderbilt University, United States)
"Accumbal D1 and D2 Medium Spiny Neurons Have Distinct and Valence-Independent Roles in Learning"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Stephan Lammel (University of California, Berkeley, United States)
"Exploring Neural Dynamics in Reward Learning and Motivated Behavior"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Markita Landry (University of California, Berkeley, United States)
"Neurochemical Imaging with Near-Infrared Neurochemical Nanosensors"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Abraham Beyene (Janelia Research Campus, United States)
"An Optical Nanosensor for Visualizing Dopamine Release at the Resolution of a Single Bouton"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Marcus Stephenson-Jones (Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, United Kingdom)
"Action Prediction Error: A Value-Free Dopaminergic Teaching Signal that Drives Stable Learning"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Jun Ding (Stanford University, United States) and Talia Lerner (Northwestern University, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Inputs and Outputs of the Basal Ganglia
Discussion Leader: Talia Lerner (Northwestern University, United States)
7:30 pm - 7:50 pm
Rui Costa (Allen Institute, United States)
"Diverse Basal Ganglia Output Circuits Mediate Different Behaviors"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Margaret Rice (New York University Grossman School of Medicine, United States)
"Regulation of Dopamine Release in the Nigrostriatal Pathway"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Aryn Gittis (Carnegie Mellon University, United States)
"Motor and Non-Motor Functions of the GPe"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Kate Wassum (UCLA, United States)
"Amygdala-Striatal Projections Enable Stress to Promote Habit Formation"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Motor Function
Discussion Leader: Lex Kravitz (Washington University in St. Louis, United States)
9:00 am - 9:20 am
Mati Joshua (The Hebrew University of Jerusalem, Israel)
"Complex Coding of Simple Movements in the Output of the Basal Ganglia"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Silvia Arber (Biozentrum, University of Basel, Switzerland)
"Licensing Actions at the Intersection Between Basal Ganglia and Brainstem"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Richard Mooney (Duke University, United States)
"Basal Ganglia Mechanisms of Vocal Learning"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Mark Bevan (Northwestern University, United States)
"Movement-Related Activity of the Subthalamic Nucleus Enhances Action Performance"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Matthew Banghart (UC San Diego, United States)
"Mechanisms of Substance P Release from Striatal Direct Pathway Neurons"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Motor Disorders
Discussion Leader: Alexandra Nelson (University of California, San Francisco, United States)
7:30 pm - 7:50 pm
Rosario Moratalla (Instituto Cajal, CSIC, Spain)
"Neural Circuits Involved in Non-Motor Symptoms of Parkinson`s Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Karunesh Ganguly (UCSF, United States)
"Modulating Corticostriatal Communication to Enhance Reach to Grasp Function"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Jim Surmeier (Northwestern University, United States)
"Network Determinants of Disability in Parkinson’s Disease"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Philip Starr (University of California, San Francisco, United States)
"Use of Motor Network Oscillatory Activity to Drive Closed Loop Neurostimulation"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Basal Ganglia and Decision-Making
Discussion Leader: Arif Hamid (University of Minnesota, United States)
9:00 am - 9:20 am
Bernardo Sabatini (Harvard Medical School / Howard Hughes Medical Institute, United States)
"Mechanisms of Rapid, Value-Dependent Updating Dopamine Signaling"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Julia Cox (Northwestern University, United States)
"Cost and Benefit in the Dorsomedial Striatum"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Miriam Matamales (University of New South Wales-Sydney, Australia)
"Striatal Substrates Supporting Flexibility of Goal-Directed Action"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Ann Graybiel (Massachusetts Institute of Technology, United States)
"A Tale of Two Circuits"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Matteo Carandini (University College London, United Kingdom)
"The Dorsal Striatum Mirrors the Cortex"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Computation in the Basal Ganglia
Discussion Leader: Veronica Alvarez (National Institutes of Health, United States)
7:30 pm - 7:50 pm
Randall O'Reilly (University of California Davis, United States)
"How the Ventral Striatum Organizes Goal-Driven Behavior: A Systems-Neuroscience Computational Model"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Karel Svoboda (Allen Institute for Neural Dynamics, United States)
"Neural Mechanisms Underlying Planning and Movement"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Jonathan Rubin (Department of Mathematics, University of Pittsburgh, United States)
"Roles of Basal Ganglia Components in Decision-Making"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Michael Frank (Brown University, United States)
"Dissecting Decision Boundary Dynamics in Human Basal Ganglia"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Stress and Addiction
Discussion Leader: Erin Calipari (Vanderbilt University, United States)
9:00 am - 9:20 am
David Lovinger (National Institute on Alcohol Abuse and Alcoholism, NIH, United States)
"Role of the Striatal Direct Pathway in Alcohol Drinking"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Michael Bruchas (University of Washington, United States)
"Dynamic Neuropeptide Modulation Shapes Goal-Directed Behavior"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
Hugo Tejeda (National Institute of Mental Health, United States)
"Dissociable Control of Motivation and Reinforcement by Distinct Ventral Striatal Dopamine Receptors"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
Julia Lemos (University of Minnesota, United States)
"CRF Release from a Distinct Population of Accumbal Neurons Constrains Outcome-Action Acquisition"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Mary Kay Lobo (University of Maryland School of Medicine, United States)
"Basal Ganglia Cell Type Molecular Signatures in Addictive Drug Exposure and Abstinence"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Autism and Affect
Discussion Leaders: Jun Ding (Stanford University, United States) and Talia Lerner (Northwestern University, United States)
7:30 pm - 7:50 pm
Mitsuko Watabe-Uchida (Harvard University, United States)
"What is Dopamine Signaling?"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Helen Bateup (University of California, Berkeley, United States)
"Synaptic Changes in the Striatum Drive Autism-Related Behaviors in Mice"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Camilla Bellone (University of Geneva, Switzerland)
"Unveiling the Role of Ventral Striatum in Decoding Social Valence"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Jones Parker (Northwestern University, United States)
"Nigrostriatal Circuit Dysfunction in Neuropsychiatric Disease"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure