| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | New Tools |
| Discussion Leader: Bernhard Hauer (BASF AG) |
| 7:30 pm - 8:05 pm | Virginia Cornish (Columbia University)
"Co-Opting Nature's Machineries for Chemical Discovery" |
| 8:05 pm - 8:40 pm | Chi-Huey Wong (Scripps)
"Enzymes in the Synthesis of Complex Carbohydrates and Glycoproteins" |
| 8:40 pm - 9:15 pm | Manfred Reetz (Max-Planck-Institut, Mülheim)
"CASTing as an Efficient Method in Directed Evolution" |
| 9:15 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Novel Biocatalysis |
| Discussion Leader: Manfred Schneider (University of Wuppertal) |
| 9:00 am - 9:35 am | Karl Hult (KTH, Stockholm)
"Exploiting the protein scaffold of Candida antarctica lipase B." |
| 9:35 am - 10:10 am | Romas Kazlauskas (University of Minnesota)
"How to change the catalytic activity of an enzyme" |
| 10:10 am | Coffee Break |
| 10:40 am - 11:15 am | Jean-Louis Reymond (University of Bern)
"A peptide dendrimer approach to artificial proteins" |
| 11:15 am - 11:50 am | Thomas Ward (University of Neuchatel)
"Artificial Metalloenzymes for Enantioselective Catalysis Based on the Biotin-Avidin Technology" |
| 11:50 am - 12:15 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Processes I |
| Discussion Leader: Jeffrey Moore (Merck) |
| 7:30 pm - 8:05 pm | Scott Novick (BioCatalytics)
"Development of a New Broad-Range D-Amino Acid Dehydrogenase" |
| 8:05 pm - 8:40 pm | William Schroeder (Cargill)
"myo-Inositol Oxygenase: a Novel Biocatayst for a New Industrial Process" |
| 8:40 pm - 9:15 pm | Richard Lloyd (Dowpharma)
"Nitrilase Catalysed Desymmetrisation of 3-Hydroxyglutaronitrile: Preparation of a Statin Side Chain Intermediate" |
| 9:15 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Redox Catalysis |
| Discussion Leader: Andreas Bommarius (GeorgiaTech) |
| 9:00 am - 9:35 am | Chris Walsh (Harvard Medical School)
"Oxidative Strategies for Enzymatic Halogenations" |
| 9:35 am - 10:10 am | Karl-Heinz van Pee (Technical University of Dresden)
"The taming of the bleach: hypochlorite as regioselective halogenating agent in biological halogenation" |
| 10:10 am | Coffee Break |
| 10:40 am - 11:15 am | Nico Vermeulen (Vrije Universiteit, Amsterdam)
"Cytochrome P450 BM3 and mutants: Towards binding and metabolism of drugs and drug-like molecules" |
| 11:15 am - 11:50 am | Willem van Berkel (University of Wageningen)
"Expanding the biocatalytic repertoire: new flavoenzymes from plants" |
| 11:50 am - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Laboratory Evolution |
| Discussion Leader: Oliver May (DSM) |
| 7:30 pm - 8:05 pm | John Gerlt (University of Illinois)
"Structural Basis for Enzyme Specificity: Evolving and Discovering New Enzymes in the Enolase Superfamily" |
| 8:05 pm - 8:40 pm | Dan Tawfik (Weizmann Institut of Science)
"Enzyme evolution - a reconstructive approach" |
| 8:40 pm - 9:15 pm | Grace DeSantis (Diversa)
"Tools for the development and refinement of Biocatalysts" |
| 9:15 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Processes II |
| Discussion Leader: Bob DiCosimo (DuPont) |
| 9:00 am - 9:35 am | Lori Giver (Codexis)
"Evolution of Biocatalysts for Highly Efficient Pharmaceutical Processes" |
| 9:35 am - 10:10 am | Sharon Haynie (DuPont)
"Fermentative and Biocatalytic Processes to Prepare p-Hydroxycinnamic Acid and p-Hydroxystyrene" |
| 10:10 am | Coffee Break |
| 10:40 am - 11:15 am | John W. Wong (Pfizer)
"Scaling Biocatalytic Processes: The Good, the Bad, and the Ugly" |
| 11:15 am - 11:50 am | David Pollard (Merck)
"Biocatalytic synthesis of chiral intermediates: challenges for early stage drug development" |
| 11:50 am - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | Carbohydrates |
| Discussion Leader: Bettina Rosche (UNSW Sydney) |
| 7:30 pm - 8:20 pm | Steve Withers (UBC)
"Teaching old enzymes new tricks: Design, engineering and evolution of enzymes for glycoside synthesis" |
| 8:05 pm - 8:40 pm | Sabine Flitsch (University of Manchester)
"Biocatalysis on Solid Support" |
| 8:40 pm - 9:15 pm | Rob Field (University of East Anglia)
"Manipulating sugar-nucleotides" |
| 9:15 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Future Trends |
| Discussion Leader: David Dodds (Dodds & Associates LLC) |
| 9:00 am - 9:35 am | Homme Hellinga (Duke University)
"Structure-based enzyme design" |
| 9:35 am - 10:10 am | Barbara Methe (TIGR)
"The use of genomic approaches to the discovery of new enzymes" |
| 10:10 am | Coffee Break |
| 10:40 am - 11:15 am | Wilfried van der Donk (University of Illinois)
"Using lantibiotic synthetases for protein engineering" |
| 11:15 am - 11:50 am | Hideo Mori (Kyowa Hakko Kogyo)
"Minimum Genome Factory - Improvement of basic cellular activity" |
| 11:50 am - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Future Trends |
| Discussion Leaders: Alex Zaks (Schering-Plough) & Nicholas Turner (University of Manchester) |
| 7:30 pm - 8:05 pm | Jürgen Pleiss (University of Stuttgart)
"The impact of protein dynamics on function: modeling of long-range effects" |
| 8:05 pm - 9:00 pm | Selected Poster Presentations |
| 9:00 pm - 9:15 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
