THURSDAY |
4:00 pm - 9:00 pm | Arrival and check-in |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Banquet (joint with Metals in Biology) |
7:30 pm - 9:30 pm | JOINT SESSION WITH METALS IN BIOLOGY |
7:30 pm - 8:30 pm | Introduction: John Dawson (University of South Carolina) |
8:30 pm - 9:30 pm | JoAnne Stubbe (Massachusetts Institute of Technology)
"Ribonucleotide Reductases: Something for Everyone" |
9:30 pm - | Poster Session (Presented by GRS) |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Conference Photo |
9:00 am - 12:30 pm | BIOMIMETIC INORGANIC CHEMISTRY |
| Discussion Leader: Patrick Holland (University of Rochester) |
9:15 am - 9:45 am | Liviu Mirica (Stanford University)
"Investigation of Tyrosinase-like Reactivity for a Cu/O2 Complex: Insights into the Phenol Hydroxylation Mechanism" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Priscilla Lugo-Mas (University of Washington)
"How Does Single Oxygen Atom Addition Affect the Properties of an Fe- Nitrile Hydratase Analogue?" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Yunho Lee (Johns Hopkins University)
"Sulfur Ligand Containing Copper Complexes and Oxidative Reactivity" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Faith Jacobsen (UC San Diego)
"Cobalt(II) Substituted Model Complexes as Aides to Zinc(II)- Metalloprotein Inhibitor Design" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Ivan Korendovych (Tufts University)
"Oxygen Binding and Activation by Biomimetic Iron Complexes with Amide-containing Pentadentate Macrocyclic Ligands" |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
5:00 pm - 6:00 pm | Optional Tutorial Lecture on the Chemistry of Metals and Nucleic Acids
Sheila David (University of Utah) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | METAL UPTAKE AND REGULATION |
| Discussion Leader: Deborah Zamble (University of Toronto) |
7:45 pm - 8:15 pm | Nathaniel Lim (University of British Columbia)
"Fluorescent Sensors for Intracellular Zinc" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Misha Golynskiy (UC San Diego)
"DNA-binding and mechanistic insights into MntR, a manganese regulatory protein" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Eric Schreiter (Massachusetts Institute of Technology)
"Structural Analysis of NikR Repressor Function" |
9:25 pm - 9:30 pm | Discussion |
SATURDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | METALLOPROTEIN (STRUCTURE, FUNCTION & CATALYSIS) |
| Discussion Leader: Donald Kurtz (University of Georgia) |
9:15 am - 9:45 am | Amit Kumar (Medical College of Wisconsin, Milwaukee)
"Mapping the substrate binding site in leucine aminopeptidase: EPR and Computer Docking" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Hee Jung Hwang (University of Illinois at Urbana-Champaign)
"pH-Dependent Transition between Delocalized and Trapped Valence tates of a CuA Center and its Possible Role in Proton-coupled Electron Transfer" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Joseph Emerson (University of Minnesota)
"A Pair of Cambialistic Extradiol Dioxygenases" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | John Magyar (California Institute of Technology)
"Probing denatured-state dynamics in cytochrome c using electron-transfer kinetics" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Matthew Sazinski (Northwestern University)
"The Role of Component Interactions in the Mechanism and Tuning of Soluble Methane Monooxygenase" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | ENVIRONMENTAL BIOINORGANIC CHEMISTRY |
| Discussion Leader: Lawrence Wackett (University of Minnesota) |
7:45 pm - 8:15 pm | Luke Moe (University of Wisconsin-Madison)
"Investigations into the origin of regiospecificity in the toluene 4-monooxygenase from Pseudomonas mendocina KR1" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Erin Bertrand (Bates College)
"Substrate-based mechanistic inquiries into alkane hydroxylation by AlkB in Pseudomonas putida GPo1 and uncharacterized alkane hydroxylases in bacteria from extreme environments" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Davin Malasarn (California Institute of Technology)
"The Genetics and Biochemistry of Respiring on Arsenic" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm - 10:00 pm | Business Meeting |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | BIOINORGANIC SPECTROSCOPY |
| Discussion Leader: Michael Hendrich (Carnegie Mellon University) |
9:15 am - 9:45 am | Andrea Decker (Stanford University)
"Oxygen Intermediates in Mononuclear Non-Heme Iron Sites: Electronic Structure and Reactivity" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Sebastian Stoian (Carnegie Mellon University)
"Diketiminate Complexes Relevant to Nitrogen Fixation: Spectroscopy of High-Spin Fe(I) Complexes" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Troy Stich (University of Wisconsin-Madison)
"Cobalamin Alkyltransferases: Spectroscopic Evidence for Enzyme Induced Activation for the Reduction of Co2+Cobalamin to Co1+Cobalamin" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Bill Gunderson (Carnegie Mellon University)
"Spectroscopic Characterization of a catalytic intermediate in the reaction of peroxide with Fe-TAML" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Abhishek Dey (Stanford University)
"S K-edge XAS: Applications to Bio-inorganic Chemistry of Iron-Sulfur Active Sites in Enzymes and Model Systems" |
12:30 pm | Lunch / Departure |