THURSDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 8:45 pm | Joint Session with Metals in Biology |
| Discussion Leader: David M. Dooley (Montana State University) |
7:30 pm - 8:30 pm | Amy Rosenzweig (Northwestern University)
"The Quest for the Particulate Methane Monooxygenase Active Site" |
8:30 pm - 8:45 pm | Discussion |
8:45 pm | Joint Poster Session (presented by Gordon Research Seminar) |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Metalloprotein Folding and Structure |
| Discussion Leader: Kara Bren (University of Rochester) |
9:15 am - 9:45 am | Leah Blasiak (Massachusetts Institute of Technology)
"Crystal Structure of Pseudomonas syringae SyrB2: Insights into the Catalytic Mechanism of a Mononuclear Fe(II)/ -Ketoglutarate-Dependent Chlorinating Enzyme" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Olga Iranzo (University of Michigan)
"Folding and assembly of De Novo designed peptides: the interplay between metal ion and peptide preferences" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Corey Wilson (Rice University)
"The Folding Nucleus in Pseudomonas aeruginosa Azurin: The Role of Structural Determinants, Metal, and Solvation" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Angela Fleischhacker (University of Michigan)
"Factors influencing protein conformation in cobalamin-dependent methionine synthase" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Lea Vacca (University of Rochester)
"The role of heme pocket dynamics and folding in the modulation of cytochrome c redox potential" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Synthetic Models of Metalloprotein Active Sites |
| Discussion Leader: Lisa Berreau (Utah State University) |
7:45 pm - 8:15 pm | Heather Lucas (Johns Hopkins University)
"Ligand effects on the photoinitiated CO/O2 binding in mononuclear copper complex systems" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Ewa Szajna-Fuller (Utah State University)
"Aliphatic Carbon-Carbon Bond Cleavage Reactivity of a Mononuclear Ni(II) Cis-Beta-Keto-Enolate Complex in the Presence of Base and O2: A Model Reaction for Acireductone Dioxygenase (ARD)" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Paul Oldenburg (University of Minnesota)
"Design of Bio-inspired Nonheme Iron Catalysts for Olefin cis-Dihydroxylation" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm | Poster Session |
SATURDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Metal Ion Sensing and Homeostasis |
| Discussion Leader: Seth Cohen (University of California - San Diego) |
9:15 am - 9:45 am | Kassy Mies (Duke University)
"Ternary Complex Formation Facilitates a Redox Mechanism for Iron Release from a Siderophore" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Joseph Collins (Yale University)
"Spectro-potentiometric Investigation of the Complexation of Titanium(IV) by Ascorbate in Aqueous Solution" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Melinda Harrison (Dusquene University)
"Investigating a cysteine rich motif in metalloproteins" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Jack Allen (Duke University)
“Fluorescent enhancement of a Tb3+ bound probe while docking to Trp rich domain of X- linked Inhibitor of Apoptosis Protein (XIAP)” |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Mi Hee Lim (Massachusetts Institute of Technology)
“Metal-Based Turn-On Fluorescent Probes for Sensing Nitric Oxide” |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Physical and Computational Methods |
| Discussion Leader: Louis Noodleman (The Scripps Research Institute) |
7:45 pm - 8:15 pm | Amanda Brooks (University of Wisconsin - Madison)
"Spectroscopic and Computational Studies of Adenosylcobalamin- Dependent Isomerases" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Kari Stone (Pennsylvania State University)
"Spectroscopic Studies of High-Valent Intermediates of Chloroperoxidase" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Alexander Gunn (University of California - Davis)
"High Field Pulsed EPR/ENDOR of Oxygen Evolving Complex of Photosystem II" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm | Poster Session |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Metalloenzyme Kinetics and Mechanism |
| Discussion Leader: Diane Cabelli (Brookhaven National Labs) |
9:15 am - 9:45 am | Melisa Cherney (University of Wisconsin - Madison)
"Ferrous Human Cystathionine Beta-Synthase Undergoes a Ligand Switch to an Inactive Species Under Assay Conditions" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Yen Nguyen (California Institute of Technology)
"Wiring Inducible Nitric Oxide Synthase" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Hein Wijma (Leiden Institute of Chemistry)
"Catalytic Cycle of Copper-containing Nitrite Reductase Investigated by Protein Film Voltammetry" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Amie Boal (California Institute of Technology)
"A Redox Role for the Iron-Sulfur Cluster in BER Enzymes: Do MutY and Endo III Use DNA-Mediated CT to Search for Damage Cooperatively In Vivo?" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Nur Basak Surmeli (Princeton University)
“Selectivity of protein tyrosine nitration by peroxynitrite: Nitration of Escherichia coli Manganese Superoxide Dismutase” |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm | Depart |