| THURSDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 8:45 pm | JOINT SESSION WITH "METALS IN BIOLOGY" |
| Discussion Leader: Robert A. Scott (University of Georgia) |
| 7:30 pm - 8:30 pm | Chris T. Walsh (Harvard University)
"Enzymatic Strategies for Halogenative Tailoring of Natural Product Scaffolds" |
| 8:30 pm - 8:45 pm | Discussion |
| 8:45 pm | Joint Poster Session (presented by the Gordon Research Seminar) |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 11:20 am | METALLOENZYME MECHANISM AND FUNCTION |
| Discussion Leader: Ruma Banerjee (University of Nebraska - Lincoln) |
| 9:15 am - 9:45 am | Emily Derberyshire (University of California - Berkeley)
"Mechanistic Studies of Soluble Guanylate Cyclase" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:20 am | Dominique Padovani (University of Nebraska - Lincoln)
"Insights into B12-dependent methylmalonyl-CoA mutase maturation" |
| 10:20 am - 10:25 am | Discussion |
| 10:25 am - 10:55 am | Eranda Perera (Duquesne University)
"Metabolic pathway of Roxarsone" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:20 am | Coffee Break |
| 11:20 am - 12:30 pm | DATA BLITZ |
| (A series of 5-minute presentations selected from the poster session) |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | COMPUTATIONAL INSIGHTS INTO METALLOENZYME ELECTRONIC STRUCTURE |
| Discussion Leader: Thomas Brunold (Univ. Wisconsin - Madison) |
| 7:45 pm - 8:15 pm | Michael Newcomer (Yale)
"A self-consistent QM/MM method with geometry relaxation for the description of electrostatic potentials in biological molecules with embedded metal centers" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:50 pm | Shengfa Ye (Bonn University)
"Theoretical Studies of High-Valent FeO2 in TauD and related FeNO systems" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:25 pm | Laurie Grove (Univ. Wisconsin - Madison)
"Computational Studies on Iron Superoxide Dismutase: Insight into Second Sphere Tuning of the Iron Reduction Potential" |
| 9:25 pm - 9:30 pm | Discussion |
| 9:30 pm | Poster Session |
| SATURDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | METAL COFACTOR BIOSYNTHESIS/INCORPORATION |
| Discussion Leader: Dennis Dean (Virginia Tech) |
| 9:15 am - 9:45 am | Robert Igarashi (University of California - Berkeley)
"Transformations of the NifB-co FeS cluster during FeMo-co biosynthesis" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:20 am | Kim Burkhard (University of Maryland)
"In vitro studies on the heme-uptake system of Shigella dysenteriae" |
| 10:20 am - 10:25 am | Discussion |
| 10:30 am - 10:45 am | Coffee Break |
| 10:45 am - 11:15 am | Jyotishman Dasgupta (Princeton University / University of California - Berkeley)
"Photoassembly of the Oxygen Evolving Complex in Photosystem II" |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:50 am | Kalyan C. Kondapalli (Wayne State University)
"Iron Binding Studies of Yeast Frataxin" |
| 11:50 am - 11:55 am | Discussion |
| 11:55 am - 12:25 pm | Shanna Potter (California Institute of Technology)
"Genetic and biochemical studies of phototrophic Fe(II) oxidation by Rhodopseudomonas palustris TIE-1" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | STRUCTURE DETERMINATION |
| Discussion Leader: Timothy Machonkin (Whitman College) |
| 7:45 pm - 8:15 pm | Yulia Puskar (Lawrence Berkeley National Labs)
"Structure and Function of the OEC in Photosystem II" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:50 pm | Jason Kowalski (Medical College of Wisconsin)
"Metal Binding Sites in alpha-Synuclein" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:25 pm | Joshua Muia (Western Michigan University)
"Structure and Function of the N-Terminal Metal-Binding Domains of Human Wilson Protein" |
| 9:25 pm - 9:30 pm | Discussion |
| 9:30 pm | Poster Session |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | BIOINSPIRED/APPLIED BIOINORGANIC CHEMISTRY |
| Discussion Leader: Cora MacBeth (Emory University) |
| 9:15 am - 9:45 am | Siu Wah Wong-Deyrup (University of Iowa)
"DNA sequence selectivity and kinetic properties of a de novo designed chimeric dimers: Are two better than one?" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:20 am | Richard M. Watson (Carnegie Mellon Univ.)
"Metal-mediated 'Base Pairs' in Peptide Nucleic Acid Duplexes" |
| 10:20 am - 10:25 am | Discussion |
| 10:25 am - 10:45 am | Coffee Break |
| 10:45 am - 11:15 am | Siddhartha Das (Yale)
"Molecular recognition in the regio- and stereoselective oxygenation of saturated C-H bonds by a dimanganese catalyst - a bio-inspired approach" |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:50 am | Matt Kieber-Emmons (University of Delaware)
"Oxygen Activation at Mono-Valent Nickel" |
| 11:50 am - 11:55 am | Discussion |
| 11:55 am - 12:25 pm | Arani Chanda (Carnegie Mellon Univ.)
"Fe(V)-oxo Complex" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm | Depart |
