THURSDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Joint Session with the Metals in Biology GRC |
| Discussion Leader: Ann Walker (U. Arizona) |
7:30 pm - 8:30 pm | Alison Butler (University of California, Santa Barbara) "Elements of the High Seas: The Bioinorganic Chemistry in the Marine Environment" |
8:30 pm - 8:45 pm | Discussion |
8:45 pm | Joint Poster Session (presented by the Bioinorganic Chemistry GRS) |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Metals in Extreme Environments |
| Discussion Leader: Ann Valentine (Yale University) |
9:15 am - 9:45 am | Tyler Grove (Pennsylvania State University)
"A Radically Different Mechanism for S-adenosylmethionine-dependent Methyltransferases Exhibited by the Antibiotic Resistance Protein Cfr and its Homologue RlmN" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Trinity Hamilton (Montana State University) "Biological Nitrogen Fixation in the Yellowstone Geothermal Complex" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Yan Kung (MIT) "Structural investigations of a metalloenzyme complex enabling microbial growth on CO2" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Joseph Braymer (University of Michigan) "Development of Bifunctional Small Molecules that Target Metal-Amyloid-β Species" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Benoit Desguin (Universite Catholique de Louvain) "Biochemical characterization of the lactate racemase of Lactobacillus plantarum: a new member of the nickel-enzyme family" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 8:55 pm | Bioinorganic Methods and Technique Development |
| Discussion Leader: Sean Elliott (Boston University) |
7:45 pm - 8:15 pm | Michael Winter (University of California, Berkeley) "Heme Protein Receptors for Diatomic Gas Sensing and Signaling" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Jeffrey Brodin (University of California, San Diego) "Construction of highly ordered protein-based materials using coordination chemistry" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:30 pm | Data Blitz |
| A series of 5-minute presentations |
|
- Joshua Hayden (Carnegie Mellon University)
- Chelsea McIntosh (Arizona State University)
- Abdullahi Sobola (Rhodes University)
- Bruno Cardey (University of Tromsø)
- Katarzyna Grubel (Utah State University)
|
SATURDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Modeling and Characterizing Metalloenzyme Active Sites |
| Discussion Leader: Andy Borovik (University of California, Irvine) |
9:15 am - 9:45 am | Katie Ellis (Boston University) "Investigating electron transfer and catalysis of bacterial cytochrome c peroxidases" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Alexey Silakov (Max-Planck Institute for Bioinorganic Chemistry) "Electronic structure of the H-cluster in [FeFe] hydrogenase" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Mary Krause (Kansas University) "Site-specific chiral inversion within a Ni-tripeptide complex generates a Ni-SOD mimic" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Aalo Gupta (University of Minnesota) "Synthesis and Characterization of O2-Reactive Bioinspired Cu(I) complexes and their Intermediates" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | David Lacy (University of California, Irvine) "Synthesis and Reactivity of High-Spin Non-Heme Oxoiron(IV) complexes" |
12:25 am - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 8:55 pm | Metal Homeostasis in the Cell and Environment |
| Discussion Leader: John Magyar (Barnard) |
7:45 pm - 8:15 pm | Colin Correnti (University of Washington) "Siderocalins: Siderophore Binding Sentinels of the Innate Immune System" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Carl Patterson (University of Durham) "The discernment of metals by a set of bacterial transcriptional regulators" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:30 pm | Data Blitz |
| A series of 5-minute presentations |
|
- Maria-Eirini Pantelia (Max-Planck Institute for Bioinorganic Chemistry)
- Lars Plate (University of California, Berkeley)
- Sambuddha Banerjee (Duke)
- Ning Li (Pennsylvania State University)
- Pamela Sontz (Caltech)
|
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Metal Clusters and Cofactors in Biology |
| Discussion Leader: Sonya Franklin (Monsanto) |
9:15 am - 9:45 am | Heather Williamson (Caltech) "Introducing Multiple Redox-active Residues in Pseudomonas aeruginosa azurin to Facilitate Ultrafast Intra-molecular Photo-oxidation" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Kim Chung (University of Toronto) "Capturing the nickel insertion complex of E. coli [NiFe] hydrogenase" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Joseph Cotruvo (MIT) "Mechanism of assembly of the dimanganese(III)-tyrosyl radical cofactor of E. coli class Ib ribonucleotide reductase in vitro and in vivo" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Avneesh Saini (University of South Carolina) "SufD and SufC ATPase activities are required for iron acquisition during in vivo Fe-S cluster formation on SufB" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Anja Pomowski (University of Freiburg) "Structure of purple nitrous oxide reductase - New Insights into CuZ" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm | Departure |