THURSDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 8:45 pm | Joint Session with the Metals in Biology GRC |
| Discussion Leader: Elizabeth C. Theil (Children's Hospital Oakland Research Institute) |
7:30 pm - 8:30 pm | Ken Nealson (University of Southern California)
"Extracellular Electron Transport (EET): a Different Look at Metals in Biology" |
8:30 pm - 8:45 pm | Discussion |
8:45 pm | Joint Poster Session |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Metalloproteins: Structure, Function and Mechanism |
| Discussion Leader: Jennifer C. Lee (NIH) |
9:15 am - 9:45 am | Christina Zimanyi (MIT)
"Structural Basis for Inhibition of Electron Transfer in a Class Ia Ribonucleotide Reductase" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Amie Boal (Northwestern University)
"Structural Basis for Methyl Transfer by a Radical SAM Enzyme" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Chi-Chung Lee (UC Irvine)
"Unique Features of the Nitrogenase VFe Protein from Azotobacter vinelandii" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Pamela Sontz (CalTech)
"DNA Charge Transport as a First Step in Lesion Detection by Repair Proteins: Atomic Force Microscopy to Visualize Enzyme Distribution" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Sarah Chobot (Cornell University)
"Characterization of a novel bacterial nitric oxide synthase from Synechococcus" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Bioinorganic Materials and Assemblies |
| Discussion Leader: F. Akif Tezcan (UC San Diego) |
7:45 pm - 8:15 pm | Melissa Zastrow (University of Michigan)
"Hydrolytic catalysis and structural stabilization within a de novo designed metalloprotein" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Annette Medina Morales (UC San Diego)
"Metal-templated design of protein macrocycles with metal-based chemical functionalities" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:30 pm | Data Blitz (a series of 10-minute presentations) |
|
- Jasmina Cheung-Lau (U Penn)
- Joy Gallagher (Penn State)
- Arnie De Leon (Carnegie Mellon University)
|
SATURDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Spectroscopic and Computational Insights into Bioinorganic Chemistry |
| Discussion Leader: Serena DeBeer (Max-Planck-Institut für Bioanorganische Chemie) |
9:15 am - 9:45 am | Joseph Cotruvo (MIT)
"Mechanism of assembly of the dimanganese(III)-tyrosyl radical cofactor of class Ib ribonucleotide reductase" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Benjamin Stein (University of New Mexico)
"C-H bond activation and transition state stabilization in xanthine oxidase" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Katlyn Meier (Carnegie Mellon University)
"An [O=FeV=NR]+ Center Formed by One-Electron Oxidation of an Oxoiron(IV) Complex" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Bruno Fonseca (ITQB-UNL)
"A novel strategy to obtain specific isotopic labeling of multiheme cytochromes c: applications to the extracellular respiratory metabolism of Shewanella oneidensis MR-1" |
11:50 am - 11:55 am | Discussio |
11:55 am - 12:25 pm | Tim Yosca (Penn State)
"Determination of the ferryl pKa: Understanding C-H bond activation in cytochrome P450" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Bioinorganic Chemistry in the Environment, Human Health, and Disease |
| Discussion Leader: Seth M. Cohen (UC San Diego) |
7:45 pm - 8:15 pm | Margaret Brown (UC Berkeley)
"Exploring enzymatic diversity in the environment: Discovery and characterization of enzymes from lignolytic soil bacteria" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Maria Telpoukhovskaia (University of British Columbia)
"Multifunctional Copper and Zinc Ion Chelators as Potential Drugs for Alzheimer's Disease" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:30 pm | Data Blitz (a series of 10-minute presentations) |
|
- Temitope Olalekan (Rhodes University)
- Ingrid Span (Technische Universität München)
- Richard Lewis (UC Santa Barbara)
|
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Reactive Small Molecules |
| Discussion Leader: Patrick Holland (University of Rochester) |
9:15 am - 9:45 am | Sarina Dorazio (SUNY Buffalo)
"Paramagnetic Iron(II) Azamacrocycle Complexes as ParaCEST Contrast Agents for MRI" |
9:45 am - 9:50 am | Discussion |
9:50 am - 10:20 am | Jeremiah Scepaniak (UC Santa Barbara)
"Reactivity of terminal iron nitrides supported by bulky tris(carbene)phenylborate ligands" |
10:20 am - 10:25 am | Discussion |
10:25 am - 10:45 am | Coffee Break |
10:45 am - 11:15 am | Rupal Gupta (Carnegie Mellon University)
"Spectroscopic Characterization of Fe and Mn complexes in Trigonal Geometry" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:50 am | Caroline Saouma (University of Washington)
"Hydrogen-atom transfer reactions of homoleptic N-ligated [2Fe-2S] Rieske cluster mimics" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:25 pm | Craig Gutman (UW - Madison)
"Spectroscopic and Computational Studies of a Synthetic Functional Mimic of Fe Superoxide dismutase and Its Azide Adduct, Fe-dapsox and Fe-dapsox(N3)2, respectively" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm | Departure |