Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Surfaces and Compartments in Biology and Medicine
Discussion Leader: Ashutosh Chilkoti (Duke University, USA)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:25 pm
Dennis Discher (University of Pennsylvania, USA)
"From Nuclear Rupture and Cancer Genomics to Blocking Recognition of Tumors as 'Self'"
8:25 pm - 8:40 pm
Discussion
8:40 pm - 9:15 pm
Cees Dekker (Kavli Institute of Nanoscience Delft, The Netherlands)
"On the Spatial Organization of Chromosomes in Cells"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Characterization of Biointerfaces: Advances in Technology
Discussion Leader: Lorenzo Albertazzi (Institute for Bioengineering of Catalonia (IBEC), Spain)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:50 am
Ke Xu (University of California, Berkeley, USA)
"Spectrally Resolved, Functional Super-Resolution Microscopy"
9:50 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:20 am
Philipp Kukura (University of Oxford, United Kingdom)
"From Micelles to Membranes and Back: Monitoring Nanoscale (Dis)assembly with Interferometric Scattering Microscopy"
11:20 am - 11:35 am
Discussion
11:35 am - 12:15 pm
Jay Groves (University of California, Berkeley, USA)
"Imaging Single Molecular Binding Events in Living Cells"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Chemistry at Biointerfaces
Discussion Leader: Tagbo Niepa (University of Pittsburgh, USA)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:50 pm
Adam Perriman (University of Bristol, United Kingdom)
"Artificial Membrane Binding Proteins for Regenerative Engineering"
6:50 pm - 7:05 pm
Discussion
7:05 pm - 7:45 pm
Zev Gartner (University of California, San Francisco, USA)
"Programming Tissue Self-Organization"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Compartmentalization
Discussion Leader: Atul Parikh (University of California, Davis, USA)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:50 am
Wilhelm Huck (Radboud University, The Netherlands)
"Dissipative Adaptation as a Design Principle for Self-Dividing Structures"
9:50 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:20 am
Rumiana Dimova (Max Planck Institute of Colloids and Interfaces, Germany)
"Membrane Wetting, Engulfment, Budding and Tubulation"
11:20 am - 11:35 am
Discussion
11:35 am - 12:15 pm
Joanna Aizenberg (Harvard University, USA)
"Enzymes in Photonic Compartments"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Synthetic Cells and Organelles
Discussion Leader: Michael Booth (University of Oxford, United Kingdom)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:50 pm
Bert Poolman (University of Groningen, The Netherlands)
"Metabolic Energy Conservation and Physiochemical Homeostasis in Synthetic Cells"
6:50 pm - 7:05 pm
Discussion
7:05 pm - 7:45 pm
Zhen Gu (University of North Carolina at Chapel Hill / North Carolina State University, USA)
"Synthetic Artificial Beta Cells for Glucose-Responsive Insulin Delivery"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Molecular Assemblies on Membranes
Discussion Leader: Alex Mason (Eindhoven University of Technology, The Netherlands)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:50 am
Christine Keating (Pennsylvania State University, USA)
"Lipid Membranes in All-Aqueous Multiphase Systems"
9:50 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:20 am
Enfu Hui (University of California, San Diego, USA)
"Mechanistic Dissection of PD-1 Signaling in Reconstitution Systems"
11:20 am - 11:35 am
Discussion
11:35 am - 12:15 pm
Michael Dustin (Kennedy Institute of Rheumatology, University of Oxford, United Kingdom)
"Role of Phase Separation at Membrane Interfaces in Immune Regulation"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cell Colonies and Communities
Discussion Leader: Knut Drescher (Max Planck Institute for Terrestrial Microbiology, Germany)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:50 pm
Reza Ghadiri (The Scripps Research Institute, USA)
"Novel Therapeutics via Remodeling of Gut Microbiome"
6:50 pm - 7:05 pm
Discussion
7:05 pm - 7:45 pm
Jean-Marc Ghigo (Institut Pasteur, France)
"Bacterial Surface Polymers Promoting the Rise and Fall of Biofilms"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Biointerfaces in Medicine
Discussion Leader: Katharina Maniura (Swiss Federal Laboratories for Materials Science and Technology (Empa), Switzerland)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:50 am
Haifeng Ye (East China Normal University, China)
"Controllable Synthetic Designer Cells for Biomedical Applications"
9:50 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:20 am
Patricia Dankers (Eindhoven University of Technology, The Netherlands)
"Synthetic Supramolecular Materials in Action at Biological Interfaces"
11:20 am - 11:35 am
Discussion
11:35 am - 12:15 pm
William Wagner (University of Pittsburgh, USA)
"Virchow's Triad and the Ongoing Conundrum of Blood Biocompatibility in Cardiovascular Devices"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Late-Breaking Topics
Discussion Leaders: Daniel Müller (ETH Zurich, Switzerland) and Sam Olof (OxSyBio, United Kingdom)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:25 pm
Shelli Frey (Gettysburg College, USA)
"The Role of Membrane Composition in the Interaction of Polyglutamine Peptides with Lipid Membranes"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Marcus Taylor (Max Planck Institute for Infection Biology, Germany)
"Signal Transduction Through a DNA-Based T Cell Receptor"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Kristina Ganzinger (Max-Planck-Institute for Biochemistry, Germany)
"A Single-Step, Cell-Topography Based Mechanism for Antigen Discrimination by T Cells"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Bastiaan Buddingh (Eindhoven University of Technology, The Netherlands)
"Mimicking Intercellular Communication in an Artificial Cell-Like System"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Fatma Pir Cakmak (Pennsylvania State University, USA)
"Effects of Polyelectrolytes Content in Complex Coacervates over Vesicles and Vesicle Assemblies and Biomolecule Partitioning"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Federico Fanalista (TU Delft, The Netherlands)
"Bottom-up Assembly of a Minimal Divisome on Chip"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Zhou Xiaoyu (The Chinese University of Hong Kong, Hong Kong SAR China)
"Hydrogel-Based Artificial Cells"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure