SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Cell Lineage and Cell Fate of Ocular Surface Tissues |
| Discussion Leader: Stephen P. Sugrue (University of Florida) |
7:40 pm - 8:20 pm | Marianne Bronner (Calif. Inst. of Tech.)
"Specification of the Neural Crest" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Fiona Watt (King's College London,UK)
"Stem Cells and Differentiated Lineages in Mammalian Skin" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Biology of Stromal & Endothelial Cells: Development/Normal/Diseases |
| Discussion Leader: Vickery Trinkaus-Randall (Boston U., Boston, MA) |
9:00 am - 9:25 am | Philip Gage (U. of Michigan, Kellogg Eye Center, Ann Arbor, MI)
"Molecular Mechanisms for Establishing Cell Fates and Angiogenic Privilege in the Developing Cornea"
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9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Donna Peters (University of Wisconsin)
"Role of Integrins and ECM in Regulating Outflow Facility Through the TM" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:45 am | Akira Asari (Hyaluronan Research Institute)
"Effects of Hyaluronan Tetrasaccharides on Stemness and Corneal Wound Healing" |
10:45 am - 10:50 am | Discussion |
10:50 am - 11:15 am | Steven E. Wilson (Cleveland Clinic, Cleveland, Ohio)
"Epithelial Basement Membrane Regeneration and Myofibroblast Precursor Development in Corneas with Haze" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:35 am | Anthony J. Aldave (UCLA)
"Identification of the Genetic Basis of Posterior Amorphous Corneal Dystrophy" |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Noriko Koizumi (Doshisha University, Japan)
"Translational Research for Corneal Endothelial Regeneration" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Corneal Innervation & Neovascularization |
| Discussion Leader: James D. Zieske (Harvard/SERI) |
7:30 pm - 7:55 pm | Peter Lwigale (Rice University, Houston, TX)
"Neural-Vascular Patterning in the Anterior Eye and Establishment of Corneal Avascularity" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Tsutomu Kume (Northwestern University)
"Deletion of Foxc1 and/or Foxc2 from Neural Crest Cells Leads to Corneal Vascularization and Anterior Segment Dysgenesis" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:30 pm | Nan Gao (Wayne State University)
"CXCL10 Suppression of Hem- and Lymph-Angiogenesis in Inflamed Corneas" |
8:30 pm - 8:35 pm | Discussion |
8:35 pm - 9:00 pm | Sandeep Jain (University of Illinois, Chicago)
"Neuroregenerative Actions of Myeloid Cells in the Cornea" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | General Discussion |
9:30 pm | Poster Session (continued) |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | ECM Formation and Tissue Engineering of Cornea |
| Discussion Leader: David E. Birk (U. of S. Florida) |
9:00 am - 9:25 am | Keith Meek (Cardiff U. Cardiff UK)
"Remodeling of Corneal Stroma After Implantation of Collagen Hydrogels" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | May Griffith (IGEN, Linkoping University, Sweden)
"Regenerative Medicine Strategies for High Risk Cornea Transplantation" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:45 am | Che Connon
"Changes in Substrate Stiffness Across the Ocular Surface and Its Role in Corneal Homeostasis" |
10:45 am - 10:50 am | Discussion |
10:50 am - 11:15 am | James Funderburgh (University of Pittsburgh)
"Stem Cells as an Agent for Restoration of Corneal Transparency" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:35 am | Qiaozhi Lu (Johns Hopkins University)
"Collagen Vitrigel Based Conjunctival Equivalent for Ocular Surface Reconstruction" |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Victor Perez (University of Miami)
"Ocular Surface Inflammation: From Immunity to Keratoprosthesis" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Corneal Infections (Bacteria, Virus, Fungus) |
| Discussion Leader: Suzanne Fleiszig (UC Berkeley, Berkeley, CA) |
7:30 pm - 7:55 pm | Eric Pearlman (Case Western University, Cleveland, Ohio)
"Innate Immunity in Fungal Keratitis" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Rajamani Lakshminarayanan (Singapore Eye Research Institute)
"Balancing the Antimicrobial and Outermembrane Permeability of Branched Peptides" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:30 pm | Matilda Chan (UCSF)
"HSV-1 Us9-30 Mutant as a Candidate HSV Vaccine in a Mouse Ocular Model" |
8:30 pm - 8:35 pm | Discussion |
8:35 pm - 9:00 pm | James Chodosh (Harvard Medical School)
"The Evolution of Human Adenovirus as a Corneal Pathogen" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | General Discussion |
9:30 pm | Poster Session (continued) |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Biology of Epithelium: Development/Homeostasis/Disease |
| Discussion Leader: Julie T. Daniels (UCL Institute of Ophthalmology, London, UK) |
9:00 am - 9:25 am | Ursula Schlötzer-Schrehardt (U. of Erlangen at Nurnberg, Erlangen, Germany)
"Limbal Stem Cells and Niche Microenvironments" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Scheffer Tseng (Ocular Surface Center, Miami, FL)
"Amniotic Membrane as a Novel Regenerative Matrix" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:45 am | Carlo Iomini (Icahn School of Medicine at Mount Sinai)
"Epithelial Injury Activates Long-Range Signals of Ciliogenesis Required for Corneal Tissue Repair" |
10:45 am - 10:50 am | Discussion |
10:50 am - 11:15 am | Chia-Yang Liu (University of Cincinnati, Cincinnati, Ohio)
"Conjunctiva Epithelium Differentiation" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:35 am | TBA |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Mayumi Ueta (Kyoto Prefectural U. of Med. Kyoto, Japan)
"Ocular Surface Inflammation and Ocular Surface Epithelial Cells" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Applications of Novel Technology in Ocular Surface Research |
| Discussion Leader: James V. Jester (UC Irvine, Irvine, CA) |
7:30 pm - 7:55 pm | Michael Liebling (UCSB, Santa Barbara, CA)
"Imaging Morphogenesis and Function in Dim and Dynamic Samples" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Geraint Parfitt (UC Irvine)
"Characterization of Mouse Meibomian Gland Label-Retaining Cells by Immunofluorescent Computed Tomography (ICT)" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:30 pm | Holly Chinnery (University of Melbourne)
"Comparison of Anterior Segment Inflammation in BALB/c and C57BL/6 Mice Using Spectral Domain Optical Coherence Tomography" |
8:30 pm - 8:35 pm | Discussion |
8:35 pm - 9:00 pm | Peixuan Guo (University of Kentucky/College of Pharmacy, Lexington)
"RNA Nanotechnology for Ocular Delivery of Therapeutics" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | General Discussion |
9:30 pm | Poster Session (continued) |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Immunology/Dry Eye and Lymphangiogenesis |
| Discussion Leader: Mike E. Stern (Allergan, Irvine, CA) |
9:00 am - 9:25 am | Steve Pflugfelder (Baylor College of Med., Houston, TX)
"T Helper Cytokine Modulation of Conjunctival Growth and Differentiation" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Kazuo Tsubota (Keio U. School of Med., Tokoyo, Japan)
"Lacrimal Gland Dysfunction in VDT & Aging" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:45 am | Mindy K. Call (University of Cincinnati)
"Regulation of Lipid Synthesis and Development of Meibomian Gland Dysfunction" |
10:45 am - 10:50 am | Discussion |
10:50 am - 11:15 am | Jerry Niederkorn (Univ. Texas Southwestern Med Ctr, Dallas, TX)
"T Regulatory Cells, Trephining, and Transplantation: Effect of Cornea-Derived Neuropeptides on Ocular Immune Privilege" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:35 am | Helen Makarenkova (Scripps Research Institute)
"Manipulation of Panx1 Expression/Function Increases the Engraftment of Transplanted Lacrimal Gland Epithelial Progenitor Cells" |
11:35 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Lu Chen (UC Berkeley)
"New Insights into Corneal Lymphangiogenesis" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cell & Gene Therapy for Treating Epithelium/Endothelium/Stroma Pathology |
| Discussion Leader: Steven E. Wilson (Cleveland Clinic, Cleveland, Ohio) |
7:30 pm - 7:55 pm | Kohji Nishida (Osaka U. Grad. School of Med., Osaka, Japan)
"Stem Cell Therapy for Corneal Diseases, from Tissue Stem Cells to iPS Cells" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:15 pm | Sophie Deng (UCLA)
"Bioengineering of Human Limbal Stem/Progenitor Cells" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:30 pm | Vivien J. Coulson-Thomas (University of Cincinnati)
"Umbilical Cord Mesenchymal Stem Cells Regulate Inflammatory Response: The Vital Role of the Glycocalyx" |
8:30 pm - 8:35 pm | Discussion |
8:35 pm - 9:05 pm | Keryn Williams (Flinders University, Australia)
"Gene Therapy for Corneal Dystrophies and Disease, Where Are We?" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | General Discussion |
9:30 pm | Poster Session (continued) |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |