Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
New Insights into Host Defense and Pathogenesis
Discussion Leader: Lee Quinton (University of Massachusetts Chan Medical School, United States)
7:40 pm - 8:10 pm
Jonathan Kagan (Harvard Medical School/Boston Children's Hospital, United States)
"Initiation and Regulation of Innate Immunity"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Victor Nizet (University of California, San Diego, United States)
"Collaborating with Innate Immunity to Combat Antibiotic-Resistant Pneumonia Pathogens"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Paul Bollyky (Stanford University, United States)
"Circulating Bacteriophages and the Diagnosis of Bacterial Lung Infections"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Immune Cells in Pneumonia
Discussion Leader: Catharine Bosio (Rocky Mountain Laboratories, United States)
9:00 am - 9:25 am
Thirumala-Devi Kanneganti (St. Jude Children's Research Hospital, United States)
"Molecular Mechanisms of Innate Immunity and Inflammation in Health and Disease"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Katrin Mayer-Barber (National Institutes of Health, United States)
"The Inflammatory Lung Microenvironment at the Time of Exposure Governs Innate Resistance to SARS-CoV-2 in Mice"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Hans-Uwe Simon (Institute of Pharmacology, University of Bern, Bern, Switzerland, Switzerland)
"The Role of ion Channels in Neutrophil Extracellular Trap Formation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Julie Ledford (University of Arizona, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Bacterial Virulence in the Lung
Discussion Leader: Carlos Orihuela (The University of Alabama at Birmingham, United States)
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:10 pm
Juliane Bubeck Wardenburg (Washington University in St. Louis, United States)
"Staphylococcus and Bacteroides Pathogenesis"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Daniel Voth (University of Arkansas for Medical Sciences, United States)
"Everybody Relax: Coxiella Subversion of Human Macrophage Stress Signaling"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Nicholas Carbonetti (University of Maryland School of Medicine, United States)
"Age-Related Effects of Interferons on Outcomes of Bordetella Pertussis Infection"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Signaling Networks in Pneumonia
Discussion Leader: Sunny Shin (University of Pennsylvania Perelman School of Medicine, United States)
9:00 am - 9:25 am
Xiaoyang Hua (University of Iowa Hospitals and Clinics, United States)
"Nasal-Restricted Viral Infection Remotely Exacerbates Asthma Through B-Cell Dependent Recruitment of Inflammatory Monocytes"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Cecilia Johansson (Imperial College London, United Kingdom)
"Lung Inflammation and Disease Severity During RSV Infection"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Emily Hemann (Ohio State University, United States)
"Type III IFN Sustains Adaptive Immune Responses to Limit Pulmonary Damage After Viral Infection"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Viral Pathogenesis in Pneumonia
Discussion Leader: Ilona Jaspers (University of North Carolina at Chapel Hill, United States)
7:30 pm - 7:55 pm
Scott Biering (University of California, San Diego, United States)
"Virus-Triggered Barrier Dysfunction: Mechanism, Impact, and Intervention"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
Stephania Cormier (Louisiana State University, United States)
"The Missing Shield: How RSV Severity Stems from Inadequate IgA Defenses in the Respiratory Mucosa of Infants"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
Lisa Gralinski (University of North Carolina at Chapel Hill, United States)
"SARS-CoV-2 Pathogenesis"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Structural Cells, Lung Matrix and Other Mediators in Pneumonia Outcomes
Discussion Leader: Andrew Vaughan (University of Pennsylvania, United States)
9:00 am - 9:25 am
Wellington Cardoso (Columbia Center for Human Development, Columbia University Medical Center, United States)
"Impact of Tnr6a and Local Translation in Airway Epithelial Differentiation and Innate Immunity Development"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Rachel Scheraga (Cleveland Clinic, United States)
"TRPV4 Protects the Lung from Injury After Bacterial Pneumonia"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Nicholas Arpaia (Columbia University Irving Medical Center, United States)
"Regulation of the Alveolar Regenerative Niche by Treg Cells in Acute Respiratory Infection"
11:20 am - 11:30 am
Discussion
11:30 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Unusual Infections and Co-Infections in the Pneumonia Outcomes
Discussion Leader: Dane Parker (Rutgers New Jersey Medical School, United States)
7:30 pm - 7:55 pm
DeBroski Herbert (University of Pennsylvania, United States)
"Regulation of Helminth Immunity in the Lung"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
Gregor Gorkiewicz (Medical University of Graz, Austria, Austria)
"SARS-CoV-2 and Other Respiratory Infections"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
Eric Schmidt (Massachusetts General Hospital, United States)
"The Impact of Influenza-Induced Glycocalyx Shedding on Secondary MRSA Pneumonia"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Age, Sex and Other Factors in Pneumonia Outcomes
Discussion Leader: Luisa Morales-Nebreda (Northwestern University, United States)
9:00 am - 9:25 am
William Zacharias (Cincinnati Children's Hospital, United States)
"Inflammatory Injury and Anti-Inflammatory Therapeutics in Third Trimester Primate Lung Development"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Durga Singer (University of Michigan, United States)
"The Influence of Sex and Obesity on Pulmonary and Extrapulmonary Myeloid Responses"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Alison Carey (Drexel University College of Medicine, United States)
"Age-Specific Differences in the Innate Immune Response During Infant Respiratory Viral Infection"
11:20 am - 11:30 am
Discussion
11:30 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Neurologic Signals and Circadian Rhythms in Pneumonia Control
Discussion Leader: Jacqueline Kimmey (University of California, Santa Cruz, United States)
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:10 pm
Colin Reardon (UC Davis, United States)
"Neuroimmune Control of Acute Lung Inflammation"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Shaon Sengupta (University of Pennsylvania, United States)
"Circadian Rhythm and Pneumonia"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Isaac Chiu (Harvard Medical School, United States)
"Vagal Nociceptor Neurons Regulate Immune Responses and Respiratory Pathogen Infection Outcome"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure