| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Endocrinology of Aging |
| Discussion Leader: Marc Tatar (Brown University, Providence) |
| 7:40 pm - 8:20 pm | Holly Brown-Borg (University of North Dakota)
"Ames dwarf mouse and oxidative stress" |
| 8:20 pm - 9:00 pm | Andrew Dillin (Salk Institute for Biological Studies)
"Specifying the DAF-16 longevity network through SMK-1, a potential cofactor of DAF-16" |
| 9:00 pm - 9:30 pm | Heidi Scrable (University Of Virginia)
"p53 and IGF signaling" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Caloric Restriction |
| Discussion Leader: James Nelson (University of Texas San Antonio) |
| 9:10 am - 9:50 am | David Sinclair (Harvard Medical School)
"Having your cake: Small molecules that provide the health benefits of
CR without the side-effects" |
| 9:50 am - 10:30 am | Blanka Rogina (University of Connecticut Health Center)
"Longevity extension in calorie restricted flies is mediated by Sir2" |
| 10:30 am | Coffee Break / Photo |
| 11:00 am - 11:45 am | Richard Miller (University of Michigan)
"Gene expression and caloric restriction in the mouse" |
| 11:45 am - 12:30 pm | Barbara Horwitz (UC Davis)
"Does Overexpression of Uncoupling Proteins Mimic
Caloric Restriction?" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Cells, Replicative Senescence and Aging |
| Discussion Leader: Gary van Zant (University of Kentucky) |
| 7:50 pm - 8:15 pm | Judith Campisi (Lawrence Berkeley National Laboratory)
"Good seed, bad seed -- effects of senescent cells on tissue homeostasis" |
| 8:15 pm - 8:40 pm | Alison Lloyd (University College London)
"Signals to Cellular Senescence" |
| 8:40 pm - 9:05 pm | Shawn C. Ahmed (University of North Carolina)
"Germline immortality in C. elegans" |
| 9:05 pm - 9:30 pm | Majlinda Lako (University of Newcastle Upon Tyne, UK)
"Stress free stem cell" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Maintenance of Protein Conformation with Age |
| Discussion Leader: TBA |
| 9:10 am - 9:50 am | Rodney Levine (National Institute of Health)
"The Proteasome and Age-Related Neurodegenerative Diseases" |
| 9:50 am - 10:30 am | Ana Maria Cuervo (Albert Einstein College of Medicine)
"Consequences of Declined Autophagy in Aging" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:40 am | Marcus Fandrich (Institut für Molekulare Biotechnologie)
"Of globular proteins and amyloid fibrils: the Dr Jekyll and Mr Hyde of the polypeptide chain" |
| 11:40 am - 12:30 pm | Late Breaking Topic Talk:
Shino Nemoto
"Sirt1 transcription by Foxo proteins" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Heterogeneity and Aging |
| Discussion Leader: Thomas E. Johnson (Univ. of Colorado, Boulder) |
| 7:50 pm - 8:15 pm | J. William O. Ballard (University of Iowa)
"Drosophila simulans as a novel model for aging research" |
| 8:15 pm - 8:40 pm | Steven Wicks (Boston College)
"Natural variation in C. elegans lifespan and aging" |
| 8:40 pm - 9:05 pm | Rudi G. Westendorp (Leiden University)
"Trade offs that determine human longevity" |
| 9:05 pm - 9:30 pm | John M. Sedivy (Brown University, Providence)
"Cellular Heterogeneity" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Telomeres and Human Aging |
| Discussion Leader: Jerry W. Shay (UT Southwestern Medical Center) |
| 9:10 am - 9:45 am | William C. Hahn (Dana Farber Cancer Institute)
"Telomerase, DNA damage, and senescence" |
| 9:45 am - 10:20 am | Duncan M. Baird (University of Wales College of Medicine)
"The dynamics of human telomeres" |
| 10:20 am | Coffee Break |
| 10:45 am - 11:20 am | Fabrizio d'adda di Fagagna (IFOM-FIRC Inst. for Molecular Oncology)
"The role of DNA damage response factors in cellular senescence" |
| 11:20 am - 11:55 am | Sandy Chang (MD Anderson Cancer Center)
"Telomere dysfunction cooperates with Werner deficiency to promote
premature aging in mice" |
| 11:55 am - 12:30 pm | N.J. Samani (University of Leicester)
"Olovnikov's clock and coronary heart disease" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Business Meeting |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Keynote Speaker |
| Discussion Leader: George Martin |
| 7:30 pm - 9:30 pm | David Reznick (University of California, Riverside)
"The evolution of senescence in natural populations of guppies (Poecilia reticulata)" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Modeling Age-Related Disease |
| Discussion Leader: Cynthia Kenyon (UC San Francisco) |
| 9:10 am - 9:50 am | Richard I. Morimoto (Northwestern University)
"The Stress of Misfolded Proteins" |
| 9:50 am - 10:30 am | Gabrielle L. Boulianne (Hospital for Sick Children, Toronto)
"Genetic Modifiers of Presenilins in Drosophila" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:45 am | Rolf Bodmer (Burnham Institute)
"Control of cardiac aging in Drosophila" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Oral Presentations |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Sarcopenia |
| Discussion Leaders: Monica Driscoll (Rutgers University) & Rodger J. McCarter (University of Texas Health Science Center) |
| 7:40 pm - 8:00 pm | Christiaan Leeuwenburgh (University of Florida)
"Muscle fiber specific apoptosis and TNF-a signaling in sarcopenia is
attenuated by life-long calorie restriction" |
| 8:00 pm - 8:45 pm | Esther E. Dupont-Versteegden (University of Arkansas Medical Sciences)
"Atrophy and Apoptosis in Aging Skeletal Muscle" |
| 8:45 pm - 9:30 pm | K.S. Nair (Mayo Medical Institute)
"Mechanism of aging muscle" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
