Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Blood as a Tissue to Study and Regulate Aging
Discussion Leader: Mitsukuni Yoshida (Washington University in St. Louis, USA)
3:15 pm - 3:40 pm
Tony Wyss-Coray (Stanford University School of Medicine, USA)
"Blood as a Tissue to Study and Regulate Aging"
3:40 pm - 3:45 pm
Discussion
3:45 pm - 3:55 pm
Jonathan Lin (Washington University School of Medicine in St. Louis, USA)
"Upregulation of microRNA-150 in Aged Macrophages Promotes Age-Related Macular Degeneration"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
The "Ins": Cell Intrinsic Changes Associated with Aging
Discussion Leader: Frank Madeo (Karl-Franzens-Universität Graz, Austria)
5:30 pm - 5:40 pm
Julia Adelöf (University of Gothenburg / AstraZeneca, Sweden)
"Aging Analysis of Mice Overexpressing the Proteasome Activator PA28αβ"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
Mitsukuni Yoshida (Washington University in St. Louis, USA)
"eNAMPT as an Adipose-Derived NAD+ Biosynthetic Enzyme that Systemically Regulates Aging"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
Johanna Heid (University of Frankfurt, Germany)
"Up-Regulation of microRNA-29 Family Protects from Cardiac Hypertrophy and Fibrosis in the Novel Aging Model Nothobranchius furzeri "
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
Nelson Hsieh (Case Western Reserve University, USA)
"A Conserved KLF-Autophagy Pathway Modulates Nematode Lifespan and Mammalian Age-Associated Vascular Dysfunction"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Katja Hoedjes (University of Lausanne, Switzerland)
"The Genomic Basis of Experimental Evolution of Aging in Drosophila : How Individual SNPs Affect Lifespan"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Alejandra Hernández (European Research Institute for the Biology of Aging, University Medical Center Groningen, The Netherlands)
"Identification of Heterogeneous Senescence-Associated Transcriptional Programs"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Amiq Gazdhar (University Hospital of Bern, Switzerland)
"Gene Network Analysis of Interstitial Macrophages After Treatment with Induced Pluripotent Stem Cells Secretome (iPSC-CM) in the Bleomycin Injured Rat Lung"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Arne Søraas (Oslo University Hospital, Norway)
"Possible Reversal of Cellular Age in Transplanted Human Haematopoietic Stem Cells"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Keynote Session: Spermidine, a Natural Autophagy Inducer Against Age-Associated Disease / The "Outs": Cell Extrinsic Changes Associated with Aging
Discussion Leader: Malene Hansen (Sanford Burnham Prebys Medical Discovery Institute, USA)
9:00 am - 9:25 am
Frank Madeo (Karl-Franzens-Universität Graz, Austria)
"Spermidine, a Natural Autophagy Inducer Against Age-Associated Disease"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Elizabeth Stahl (University of Pittsburgh, USA)
"Accumulation of Bone Marrow Derived Macrophages in Aged Murine Livers"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Michael Stout (University of Oklahoma Health Sciences Center, USA)
"17a-Estradiol Acutely Acts Through Hypothalamic Proopiomelanocortin Expressing Neurons"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Andrew Rallis (Institute of Biology Valrose, France)
"The Hh Signalling Pathway Modulates Lifespan Determination and Neuroprotection in Drosophila "
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Ritchie Ho (Cedars-Sinai Medical Center, USA)
"Mechanistic Insights into Aging and ALS Pathology Using Orthologous Transcriptomic Analysis in Mice"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Markus Schosserer (University of Natural Resources and Life Sciences, Vienna, Austria)
"Two Distinct Ribosomal RNA Base Methylations Modulate Healthy Lifespan"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Oliver Hahn (Max Planck Institute for the Biology of Ageing, Germany)
"Age-Related Changes in DNA Methylation Are Retarded by Dietary Restriction and Are Associated with Reprogramming of Lipid Metabolism"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Getting Your Next Position and Funding It
Discussion Leader: Isabel Beerman (National Institutes of Health, USA)
1:30 pm - 1:50 pm
Malene Hansen (Sanford Burnham Prebys Medical Discovery Institute, USA)
"Scientific Career Transitions"
1:50 pm - 1:55 pm
Discussion
1:55 pm - 2:10 pm
Bita Nakhai (National Institute on Aging, NIH, USA)
"NIH Grant Review Process"
2:10 pm - 2:15 pm
Discussion
2:15 pm - 2:30 pm
Panel Discussion
Advice for Promoting Career Development
Malene Hansen (Sanford Burnham Prebys Medical Discovery Institute, USA)
Bita Nakhai (National Institute on Aging, NIH, USA)
Tony Wyss-Coray (Stanford University School of Medicine, USA)
Adam Antebi (Max Planck Institute for Biology of Ageing, Germany)
Shin-Ichiro Imai (Washington University in St. Louis School of Medicine, USA)
Frank Madeo (Karl-Franzens-Universität Graz, Austria)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
