Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Stem Cells, Inflammation and Aging: Strategies for Intervention
Discussion Leader: Daniel Roncancio (University of Minnesota, USA)
3:45 pm - 3:55 pm
Introduction by Discussion Leader
3:55 pm - 4:25 pm
Heinrich Jasper (Genentech, Inc., USA)
"Stem Cells, Inflammation and Aging: Strategies for Intervention"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Computational and Comparative Approaches to Aging
Discussion Leader: Nathalie Dowgray (University of Liverpool, United Kingdom)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 7:55 pm
Maarouf Baghdadi (Max Planck Institute for Biology of Ageing, Germany)
"Role of Neuronal IIS in the Dopamine Pathway"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Julia Constantinou (University of Birmingham, United Kingdom)
"Establishing and Characterizing Daphnia magna as a New Model for Research into Ageing"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Albina Ibrayeva (University of Southern California, USA)
"Early Neural Stem Cell Aging in the Adult Mouse Hippocampus"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Joseph Palmer (University of Alabama at Birmingham, USA)
"Evaluating the Transcriptomic Plasticity of Stem Cell Quiescence Depth with Age"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Thomas Stoeger (Northwestern University, USA)
"Aging Tilts the Ratio Between Short and Long Transcripts"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Frederik Dufour (University of Sherbrooke, Canada)
"Physiological Dysregulation During Aging: A Gene Expression Analysis"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Waylon Hastings (Pennsylvania State University, USA)
"Comparability of Biological Aging Measures in the National Health and Nutrition Examination Study, 1999-2002"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Emerging Techniques and Interventions in Aging
Discussion Leader: Juan Vazquez (University of Chicago, USA)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:25 am
Xiaofang Shi (University of Michigan, USA)
"Effects of FTO Inhibitors on m6A-Mediated Cap-Independent Translation and Stress Response"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Tapash Sarkar (Stanford University, USA)
"Transient Non-Integrative Epigenetic Reprogramming Promotes Multifaceted Reversal of Aging in Human Cells"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Diljeet Gill (The Babraham Institute, United Kingdom)
"Examining the DNA Methylation Age Reset that Occurs During iPSC Reprogramming"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Shijiao Huang (University of Michigan, USA)
"Cell Non-Autonomous Regulation of Longevity by the Hypoxic Response in C. elegans "
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Samir Morsli (The University of Sheffield, United Kingdom)
"Establishing a Model of Stress-Induced Senescence in Zebrafish Larvae"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Michaela Copp (University of North Carolina at Chapel Hill, USA)
"Characterization of Cellular Senescence Induction and Subsequent Elimination Within an Equine Cartilage Explant Model for the Treatment of Osteoarthritis"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Vera Pils (University of Natural Resources and Life Sciences, Vienna (BOKU), Austria)
"Lyso-Phospholipids Contribute to the Pro-Inflammatory and Immunomodulatory Activity of Senescent Fibroblasts"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Finding Your Career Path, and How to Get There
Discussion Leader: Victor Bustos (Apollo Ventures, Germany)
1:30 pm - 1:40 pm
Introduction by Discussion Leader
1:40 pm - 1:55 pm
Bita Nakhai (National Institute on Aging, NIH, USA)
"Financing Your Future by Securing Early Career Funding"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:30 pm
Panel Discussion
Many Paths Forward, but Which to Take? How to Prepare for Your Specific Future
Heinrich Jasper (Genentech, Inc., USA)
Bita Nakhai (National Institute on Aging, NIH, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes