| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:15 pm | Meeting information |
| 7:30 - 9:45 pm | CELL AND DEVELOPMENTAL BIOLOGY |
| | Discussion Leader: KEITH GULL (University of Manchester)
"The cell biology of gene expression, motility and cellular form in T. brucei" |
| CON BECKERS (University of Alabama)
"Structure and dynamics of the Toxoplasma membrane skeleton" |
| KOJO MENSA-WILMOT (University of Georgia)
"Regulation of endocytosis in trypanosomes" |
| TAMARA DOERING (Washington University)
"Capsule synthesis in the pathogenic fungus Cryptococcus neoformans" |
| PAUL ENGLUND (Johns Hopkins University)
"RNA interference in T. brucei" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | HOST CELL ATTACHMENT, INVASION AND MODIFICATION |
| Discussion Leader: DAVID SIBLEY (Washington University)
"Motility and Invasion by Toxoplasma" |
| BRUCE KLEIN (University of Wisconsin)
"Linking fungal morphogenesis, adherence, and evasion of host immunity" |
| 10:00 am | Coffee Break / Photo |
| M. JULIA MANSO-ALVES (Universidade de Sao Paulo)
"Infection by Trypanosoma cruzi: Identification of a parasite ligand and its host cell receptor" |
| GARY WARD (University of Vermont)
"Using small molecules to study host cell invasion by Toxoplasma gondii" |
| SIGRID HEINSBROEK (Oxford University)
"A role for lysosomal exocytosis during maturation of Candida albicans phagosomes in macrophages" |
| BILL BERGMAN (MCP-Hahnemann University)
"Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites" |
| VERN CARRUTHERS (Johns Hopkins University)
"Toxoplasma gondii MIC2-Associated Protein (M2AP) iis required for correct targeting, stability, and secretion of MIC2" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:45 pm | INTRACELLULAR SURVIVAL STRATEGIES |
| 7:30 pm | Discussion Leader: WILLIAM GOLDMAN (Washington University)
"Phase-specific genes and the parasitic lyfestyle of Histoplasma capsulatum" |
| | BARBARA BURLEIGH (Harvard School of Public Health)
"Is T. cruzi a stealth parasite?" |
| ARTURO CASADEVALL (Albert Einstein College of Medicine)
"Intracellular polysaccharide production as a novel strategy in macrophage subversion" |
| | TONY SINAI (University of Kentucky)
"Toxoplasma gondii: Suicide prevention by a protozoan parasite" |
| DAN GOLDBERG (Washington University)
"Genome-wide analysis of Plasmodium hemoglobin degradation" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PARASITE / VECTOR / HOST INTERACTIONS |
| | Discussion Leader: DAVID SACKS (NIH)
"Parasite-vector and vector-host interactions in Leishmaniasis" |
| ISABEL RODITI (University of Bern)
"Changes in invariant coat during trypanosome development in the tsetse fly" |
| ED HENDRIKS (University of Manchester)
"Life cycle control of African trypanosomes" |
| TONI AEBISCHER (Max Planck Institute for Infection Biology)
"Kinetic analysis of Leishmania sp with dendritic cells in vitro and in vivo using EGFP-tagged parasites" |
| 10:30 am | Coffee Break |
| DAVID SCHNEIDER (Stanford University)
"Studying Drosophila as a model vector of Plasmodium and other microbes" |
| CAROLINA BARILLAS-MURY (Colorado State University)
"Cell biology and signal transduction pathways mediating midgut epithelial cell responses to ookinete invasion" |
| TONY JAMES (University of California at Irvine)
"Development of pathogen-resistant vector mosquitoes" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:45 pm | SIGNALING AND INNATE IMMUNITY |
| Discussion Leader: RICARDO GAZZINELLI (Universidade Federal de Belo Horizonte)
"Chemokine, phagocytosis and activation of macrophages during interaction with Trypanosoma cruzi" |
| SUSAN COLLER (University of Wisconsin)
"Modulation of macrophage activation during trypanosome infection" |
| ERIC DENKERS (Cornell University)
"Subversion of Macrophage proinflamatory signaling cascades by Toxoplasma gondii" |
| DIRK DOBBELAERE (University of Bern)
"Hijacking of the IKK signalosome by transforming Theileria parasites" |
| SERGIO GRINSTEIN (Hospital for Sick Children)
"Role of phosphoinisitides in phagosome formation and maturation" |
| MICHEL DESJARDINS (Université de Montréal)
"Endoplasmic reticulum-mediated phagocytosis defines a novel mechanism of entry into macrophages" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CHEMOTHERAPY TARGETS AND RESISTANCE |
| Discussion leader: MICHAEL FERGUSON (University of Dundee)
"Glycoconjugate byosynthesis: targets against trypanosomatid parasites" |
| TED WHITE (Seattle Biomedical Research Institute)
"Drug resistance in yeasts: Pumps and permutations" |
| ROBERT DONALD (Merck Laboratories)
"Molecular characterization and validation of the Apicomplexa parasite cGMP-dependent protein kinase as a target for small molecule inhibitors" |
| 10:30 am | Coffee break |
| SILVIA MORENO (University of Urbana)
"Structure and function of acidocalcisomes in apicomplexan and trypanosomatid parasites" |
| HELEN PRICE (Imperial College)
"Myristoyl CoA protein N-myristoyl transferase as a drug target for trypanosomatid diseases" |
| GEOFF BENTLEY (University of Leeds)
"The schistosome surface cholinergic system is a target for chemotherapy" |
| STEVE BEVERLEY (Washington University)
"Pteridines as Leishmania virulence factors and targets for chemotherapy" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:45 pm | TRANSPORTERS IN INTRACELLULAR PARASITISM |
| | Discussion Leader: JENNIE BLACKWELL (Cambridge Institute for Medical Research)
"Nramps: endosomal divalent cation transporters that influence infection and autoimmunity" |
| | SCOTT LANDFEAR (University of Oregon)
"Nutrient transporters in Leishmania and African trypanosomes" |
| SENJAY DESAI (NIH)
"A voltage-dependent ion channel on P. falciparum-infected red blood cells" |
| FLORIAN LANG (University of Tubingen)
"Ion channels induced by Plasmodium falciparum in host erythrocytes" |
| | KIARAN KIRK (Australian National University)
"Nutrient acquisition by the intracellular malaria parasite" |
| PAUL ROEPE (Georgetown University)
"New biophysical approaches for studying drug resistant P. falciparum" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PROGRESS TOWARDS A MALARIA VACCINE |
| Discussion leader: VICTOR NUSSENZWEIG (New York University)
"What is the rationale for selecting liver stage malaria vaccine candidates?" |
| TONY HOLDER (National Institute for Medical Research, Mill Hill)
"Malarial merozoites, antibodies and vaccines" |
| SIMONE KORTEN (Oxford University)
"Towards protection against liver stage malaria" |
| 10:30 am | Coffee break |
| BETSY NARDIN (New York University)
"The use of transgenic parasites to evaluate P. falciparum vaccines" |
| PATRICK DUFFY (Seattle Biomedical Research Institute)
"Targeting placental parasites for a pregnancy malaria vaccine" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session 2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:45 pm | FUNCTIONAL GENOMICS |
| Discussion Leader: KEN STUART (Seattle Biomedical Research Institute)
"Dissecting the RNA-editing complex of Trypanosoma brucei" |
| JOHN BOOTHROYD (Stanford University)
"Molecular basis of host-pathogen interaction in toxoplasmosis" |
| ANGELA CRUZ (Universidade Federal de Ribeirao Preto)
"Tackling mapping and sequencing information in Leishmania" |
| NINA AGABIAN (University of California at San Francisco)
"Genomic approaches to Candida virulence" |
| JESSICA KISSINGER (University of Georgia)
"Completion of the Plasmodium falciparum genome sequence. The challenges that lie ahead". |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
