SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Co-Evolution of Host and Parasite |
| Discussion Leader: Jonathan Howard (University of Cologne, Germany) |
7:40 pm - 8:00 pm | Jonathan Howard (University of Cologne, Germany)
"New insights into the host specificity of Toxoplasma gondii" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Bill Petri (University of Virginia, USA)
"Malnutrition and infection: Leptin as a mediator of mucosal immunity to amebiasis" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:10 pm | Sabrina Krief (Museum of National History, Paris, France)
"Do chimpanzees control their malaria infections?" |
9:10 pm - 9:20 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Parasite Pathogenesis and Virulence |
| Discussion Leader: Steven Hajduk (University of Georgia, USA) |
9:00 am - 9:20 am | Steven Hajduk (University of Georgia, USA)
"Regulation of the susceptibility of African trypanosomes to human innate immunity" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | David Sibley (Washington University, USA)
"Genetic analysis of virulence in Toxoplasma" |
9:50 am - 10:00 am | Discussion |
10:00 am | Group Photo / Coffee Break |
10:30 am - 10:50 am | Nicholas Fasel (University of Lausanne, Switzerland)
"Metastatic leishmaniasis" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Ricardo Gazzineli (Foundation Oswaldo Cruz of Minas Gerais, Brazil)
"Endosomal TLRs: key sensors for protozoan parasites" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:30 pm | Short Talks |
11:30 am - 11:45 am | Suman Dhar (Jawaharlal Nehru University, India)
"Plasmodium falciparum origin recognition complex subunit 1 (PfORC1): Role in the regulation of parasite DNA replication and virulence gene expression"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Melissa Lodoen (University of California Irvine, USA)
"A fluidics approach reveals T. gondii modulation of human monocyte interactions with vascular endothelium"
|
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Katherine Ralston (University of Virginia, USA)
"Chew your food: 'partial ingestion' plays a role in host cell killing by Entamoeba histolytica"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Host Cell Invasion and Modification |
| Discussion Leader: Dominique Soldati-Favre (University of Geneva, Switzerland) |
7:30 pm - 7:50 pm | Dominique Soldati-Favre (University of Geneva, Switzerland)
"Implication of the actinomyosin system in organellar positioning and inheritance in Toxoplasma gondii" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Maryse Lebrun (University of Montpellier, France)
"Insights into the moving junction that drives the apicomplexan invasion process" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Norma Andrews (University of Maryland, USA)
"Iron and heme uptake by Leishmania amazonensis" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:30 pm | Short Talks |
9:00 pm - 9:10 pm | Allison Jackson (University of Glasgow, UK)
"Uncoupling gliding motility and invasion: Using new Toxoplasma invasion mutants to screen for host cell invasion factors"
|
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Souvik Bhattacharjee (University of Notre Dame, USA)
"Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell"
|
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
Important Note: Please be aware that the order of events on Tuesday, June 12 deviates from the standard schedule that is used on all other days of the meeting. The revised schedule is displayed below.
|
7:30 am - 8:30 am | Breakfast |
8:30 am - 10:30 am | Free Time |
10:30 am - 12:30 pm | Poster Session I |
12:30 pm | Lunch |
1:30 pm - 5:00 pm | Parasite Cell Biology |
| Discussion Leader: Kent Hill (University of California Los Angeles, USA) |
1:30 pm - 1:50 pm | Kent Hill (University of California Los Angeles, USA)
"Motility and signaling functions of the trypanosome flagellum" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Photini Sinnis (Johns Hopkins University, USA)
"The role of proteases in sporozoite Infectivity" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm | Coffee Break |
3:00 pm - 3:20 pm | Dan Goldberg (Washington University, USA)
"Chaparoning the malaria parasite through febrile stress" |
3:20 pm - 3:30 pm | Discussion |
3:30 pm - 3:50 pm | Phil Newmark (University of Illinois Urbana Champaign, USA)
"Using planarians as free-living models to understand schistosomes" |
3:50 pm - 4:00 pm | Discussion |
4:00 pm - 5:00 pm | Short Talks |
4:00 pm - 4:10 pm | Maria Francia (University of Georgia, USA)
"Apicomplexan cell division is hard wired through multiple tethers"
|
4:10 pm - 4:15 pm | Discussion |
4:15 pm - 4:25 pm | Alexander Paredez (University of California Berkeley, USA)
"Characterization of a novel player in myosin independent cytokinesis"
|
4:25 pm - 4:30 pm | Discussion |
4:30 pm - 4:40 pm | Philippe Bastin (Institut Pasteur, France)
"Different recipees to construct and to maintain flagella"
|
4:40 pm - 4:45 pm | Discussion |
4:45 pm - 4:55 pm | Dirk Dobbelaere (University of Bern)
"Theileria uses molecular mimicry to recruit a host cell microtubule plus end binding protein to its surface"
|
4:55 pm - 5:00 pm | Discussion |
5:00 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Parasite Adaptations for Survival and Development |
| Discussion Leader: Isabel Roditi (University of Bern, Switzerland) |
7:30 pm - 7:50 pm | Isabel Roditi (University of Bern, Switzerland)
"New insights into the regulation and function of trypanosome surface proteins" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Patricia Johnson (University of California Los Angeles, USA)
"Trichomonas exosomes and host-parasite interactions" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | David Horn (Liverpool School of Tropical Medicine & Hygiene, UK)
"RNAi libraries for high throughput phenotype screening in the African trypanosome" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:30 pm | Short Talks |
9:00 pm - 9:10 pm | Binny Mony (University of Edinburgh, UK)
"Dissecting the stumpy induction pathway in Trypanosoma brucei"
|
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Michael Oberholzer (University of California Los Angeles, USA)
"Social motility in Trypanosoma brucei varies among natural isolates and requires cAMP signaling"
|
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Host Parasite Metabolic Interaction |
| Discussion Leader: Malcolm McConville (Melbourne University, Australia) |
9:00 am - 9:20 am | Malcolm McConville (Melbourne University, Australia)
"Mapping pathways of Leishmania carbon metabolism essential for intracellular survival" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Elaine Holmes (Imperial College, UK)
"Mapping the dialogue between host and parasite" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Mike Ferdig (Notre Dame University, USA)
"Global metabolites, linkage, and integrated networks in malaria parasites" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Kiaran Kirk (Australian National University, Australia)
"Ionic and metabolic interactions between the malaria parasite and its host erythrocyte" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:30 pm | Short Talks |
11:30 am - 11:45 am | Barbara Burleigh (Harvard University, USA)
"Host metabolism regulates intracellular growth of Trypanosoma cruzi amastigotes"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Ian Lewis (Princeton University, USA)
"Tricarboxylic acid cycle reactions are not essential for Plasmodium falciparum"
|
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Matt Gould (University of Edinburgh)
"The Kinetoplast: Adapting to Loss and Other Tales of Resistance"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Parasite Gene Expression Control |
| Discussion Leader: Elisabetta Ullu (Yale University, USA) |
7:30 pm - 7:50 pm | Elisabetta Ullu (Yale University, USA)
"The RNA world in trypanosomes" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Michael White (University of South Florida, USA)
"AP2 factors may serve as gatekeepers of Toxoplasma development" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:30 pm | Short Talks |
8:30 pm - 8:45 pm | Laura Morf Scherer (Stanford University, USA)
"A novel small RNA dependent gene knockdown technique in the pathogenic protist Entamoeba histolytica reveals insight into the role of a Myb transcription factor during peroxide stress"
|
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Rudo Kieft (University of Georgia, USA)
"Transcriptional Regulation of the Haptoglobin/Hemoglobin Receptor Transcription Unit in Trypanosoma brucei"
|
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Nikolay Kolev (Yale University, USA)
"In vitro Metacyclogenesis of Trypanosoma brucei"
|
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Host Immune Response and Parasite Evasion |
| Discussion Leader: Yasmine Belkaid (National Institutes of Health, USA) |
9:00 am - 9:20 am | Yasmine Belkaid (National Institutes of Health, USA)
"Innate and adaptive responses to commensals during mucosal infections" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Carolina Barillas Murry (National Institutes of Health, USA)
"Mosquito immunity and malaria transmission" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Judith Allen (University of Edinburgh, UK)
"The anti-inflammatory nature of helminth-induced inflammation" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Richard Grencis (University of Manchester, UK)
"Resistance and suceptibility to gut nematodes: Innate, adaptive and absent immunity" |
11:20 am - 11:30 am | Discussion |
11:30 am - 12:30 pm | Short Talks |
11:30 am - 11:45 am | Richard Baxter (Yale University, USA)
"Molecular basis for genetic resistance of Anopheles gambiae to Plasmodium: structural comparison of TEP1 susceptible and resistant alleles"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Samarchith Kurup (University of Georgia, USA)
"Enhancing immunity to Trypanosoma cruzi by heterologous expression of TLR-ligands"
|
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Christopher Dupont (University of Pennsylvania, USA)
"A role for infected cells in the initiation of T cell responses to Toxoplasma gondii"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Drug Action and Resistance |
| Discussion Leader: Dyann Wirth (Harvard University, USA) |
7:30 pm - 7:50 pm | Dyann Wirth (Harvard University, USA)
"Harnessing genomics for malaria elimination: Insights into parasite evolution" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Matthew Bogyo (Stanford University, USA)
"A small molecule screen identifies novel regulators of host cell invasion by Toxoplasma gondii" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Deborah Smith (University of York, UK)
"Targeting post-translational modifications in kinetoplastids and Plasmodium" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:30 pm | Short Talks |
9:00 pm - 9:10 pm | Dennis Kyle (University of South Florida)
"Defining the Elusive Artemisinin Resistance Phenotype In Vitro"
|
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Marie-Claude Lafitte (Laval University, Canada)
"MRE11 involvement in DNA repair and drug resistance in Leishmania infantum"
|
9:25 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |