Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
The Structural Biology of Host-Parasite Interaction
7:40 pm - 8:00 pm
"Visualizing The Molecular Effects of an Anti-Malarial Translation Inhibitor Inside Malaria Parasites"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Toward A Structural Mechanistic Understanding of the Apicomplexan Rhoptry Secretion System at The Host-Parasite Interface"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Parasitizing Parasites: The African Trypanosome in Science and Medicine"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"Understanding the Divergent Biology of Apicomplexan Mitochondria via Structural Analysis"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Cell Biology of Parasites and Host-Parasite Interaction
9:00 am - 9:20 am
"Extracellular Vesicles from The Parasite Trichomonas Vaginalis : Role in Cell Communication"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Insights From Theileria : Commonalities in Host Cell Reprogramming and Exploitation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Preferential Host Lipid Acquisition Leading to The Breakdown of Amphotericin-B Responsiveness in Clinical Isolates of Leishmania Donovani "
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Exploring Stem Cell And Germ Cell Niches In The Tapeworm Hymenolepis Diminuta"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Cryptosporidium : A Growing (Microvilli) Problem"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Implications of Purine Auxotrophy in Toxoplasma Gondii "
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Host-Parasite Interactions of the Third Kind"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Biophysical and Mechanical Aspects of Host-Parasite Interaction
7:30 pm - 7:50 pm
"Physical Aspects of Trypanosome Biology - From Single Molecule Motion To Collective Behavior in The Host"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"How Microsporidian Parasites Use Ballistic Organelles To Invade Host Cells"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Decoding The Dynamic Interplay Between Adhesion And Force During Toxoplasma Motility"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Bridging the Gap Between Surface Flows and Motility Patterns of Malaria Sporozoites"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Identification and Characterization of a New Actor in the Regulation of the Mechanical Properties of Erythrocytes Infected with Plasmodium Falciparum "
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Parasite Genomics and Epigenetics
9:00 am - 9:20 am
"Hybridization in Urogenital Schistosomiasis (HUGS)"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Exploring The Impact of Structural Variants of PfAP2-G On Sexual Commitment"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"A Microscopy-Based CRISPR Screen Reveals The Essential Host Genome for Cryptosporidium Replication and Development"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"High-Resolution scRNA-Seq Reveals Genomic Determinants of Antigen Expression Hierarchy in African Trypanosomes"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Using Computational, Single Cell and Spatial Methods to Explore Host-Parasite Interactions"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Loss of Leishmania Mitochondrial Minicircle DNA is Associated with Attenuated Parasite Virulence in Mice"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Parasite Evolution and Population Genetics
7:30 pm - 7:50 pm
"Insecticides and Parasites: Do They Interact?"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Host-Parasite Relationship Drama: New Approaches Uncover Giardia's Secure Attachment Style"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Expanding the Menu: Novel Diversity of Free-Living Bacterivorous Colpodellids, Relatives of Apicomplexa"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Distribution of Polymorphisms in Malaria Associated Host Genes ARL15, ATP2B4, CD40, G6PD and INPP4B across Selected Malaria Endemic African Populations."
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Hide and Go Seq: Capturing the Antibody-VSG Arms Race During Trypanosoma brucei Infection"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Host Response to Infection and Parasite Countermeasures
9:00 am - 9:20 am
"Antigen Diversification in Trypanosoma Brucei "
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Blood and Bleeding: A Centerpiece of Sand Fly-Leishmania Interactions"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Trogocytosis of Human Cells by Entamoeba Histolytica Enables Protection from Human Serum Complement Lysis"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Prostaglandin Regulation of Type 2 Inflammation During Helminth Infection"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Long-Acting Antimalarials Targeting Late Liver Stages for Malaria Chemovaccination"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"A Combination of Four Nuclear Targeted Effectors Protects Toxoplasma Against Interferon Gamma Driven Human Host Cell Death During Acute Infection"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Using T. Brucei 's Unique Properties to Develop Therapeutic Antibodies against Difficult Targets in Cancer and Other Diseases"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Extended Phenotype: Parasite Manipulation of Host Behavior
7:30 pm - 7:50 pm
"The Last of (Fung)us: Mechanisms of Fruit Fly Behavioral Manipulation by The Killer Fungus Entomophthora Muscae "
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Exploiting Neurotransmitter Crosstalk: The Intricate Chemical Warfare Between A Parasitoid Wasp And its Cockroach Host"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Are we Underestimating the Prevalence of Toxoplasma Infections and their Relationship with Neuropsychiatric Disorders?"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
General Discussion
9:20 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Parasite Developmental Biology
9:00 am - 9:20 am
"Sex, Drugs, and Schistosomes: Control of Schistosome Sexual Development by A Non-Ribosomal Peptide Pheromone"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Uncovering Cell Cycle Checkpoints in Malaria Parasites"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Prospective Isolation and Molecular Characterization of Stem Cells in the Rat Tapeworm, Hymenolepis Diminuta "
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Lost in A Crowd: How Toxoplasma Manages Resources at High Density"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"The Role of Host Adipose Tissue in Trypanosomiasis"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Single-Cell RNA Sequencing and Immunohistochemical Analysis of Reactivating Toxoplasma Bradyzoites in Vivo."
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Parasite Metabolism and Drug Targets
7:30 pm - 7:50 pm
"Non-Covalent Selective Proteasome Inhibitors for Malaria"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Identification of Potent and Orally Efficacious Phosphodiesterase Inhibitors to Treat Cryptosporidiosis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Engineering Tissue-Specific Stability of Phosphatidylinositol 4-Kinase Inhibitors to Treat Pediatric Cryptosporidiosis"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Characterization of a Putative T. Brucei Fexinidazole Resistance Gene Encoding a Novel Glutathione-S-Transferase Protein"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Single Cell RNAseq Reveals the Role of Leucine-Rich Repeat Protein 5 (LRR5) in the Plasmodium Falciparum Artemisinin Response"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure