Sunday Evening, January 18
(7:30-9:30)
Evolution and Genetics
Discussion Leader--Guy Baranton
Ulf Göbel |
Diversity and ecology of novel and uncultured treponemes from chronic mixed infections in man and cattle |
John Breznak |
Biology and phylogeny of termite gut spirochetes |
Thad Stanton |
VSH-1, an unusual bacteriophage of Serpulina hyodysenteriae |
David Persing |
Genetic diversity of B. burgdorferi in the United States: A prelude to premunition? |
Monday Morning,
January 19 (9:00-12:30) Gene Organization, Expression,
and Function Discussion Leader--Masahito Fukunaga
Tom Schwan |
Common themes in protein regulation in the genus Borrelia |
Frank Gherardini |
Metal requirements of Borrelia burgdorferi |
David Nelson |
Spirochetes and spit |
Russ Johnson |
Borrelia burgdorferi: plasmids and infectivity |
Howard Kuramitsu |
Identification of virulence factors for oral spirochetes |
Monday Evening,
January 19 (7:30-9:30)
Prospecting the Genomes of Spirochetes--Where do we go from here?
Discussion Leader--Mike Norgard
Sherwood Casjens |
The B. burgdorferi chromosome and plasmids: sequences, genes, and universality. |
Rich Zuerner |
Genetic organization and rearrangement in Leptospira |
George Weinstock |
The genome of Treponema pallidum |
Tuesday Morning, January 20
(9:00-12:30)
Host-Parasite Interactions
Discussion Leader--Richard Ellen
Stephen Barthold |
Immunological relevance of B. burgdorferi antigens expressed during infection of the mammalian host |
Pam Pennington |
Genetics and structure of Vsp/OspC Proteins of Borrelia |
Jorge Benach |
Fibrinolytic system requirements for B. burgdorferi invasion |
Isabelle Saint-Girons |
Intracellular location of virulent Leptospira: Protective effects of eucaryotic cells against the action of penicillin |
Richard Ellen |
How T. denticola sheath proteins perturb the cytoskeleton of cultured cells |
Tuesday Evening, January 20
(7:30-9:30)
Spirochete Membrane Antigens
Discussion Leader--Alan Barbour
Chris Fenno |
The major surface protein (Msp) of Treponema denticola and related organisms |
David Blanco |
Tromp 1 and 2 are outer membrane proteins of T. pallidum |
Justin Radolf |
The quest for spirochetal rare outer membrane proteins: A reappraisal |
Wednesday Morning, January 21
(9:00-12:30)
Mechanisms of Pathogenesis
Discussion Leader--Sven Bergstrom
Graciela Rosen |
The major phenylalanine proteinase of T. denticola |
Sally Cutler |
B. recurrentis: Perspectives on persistance and antigenic variation |
Jing-Ren Zhang |
Genetic and antigenic variation of B. burgdorferi lipoprotein VlsE |
Arturo Centurion |
Identification of a polymorphic, multicopy gene family in pathogenic treponemes |
Wednesday Evening, January 21
(7:30-9:30) Biology and Ecology
Discussion Leader--Ulrike Munderloh
Paul Kolenbrander |
Bacterial interactions and the ecology of oral biofilms |
David Hampson |
Serpulina pilosicoli: Population genetics, pathogenesis and control |
Ron Limberger |
Determining the role of cytoplasmic filaments and the unique aqueous protein Tap1 in treponemal motility |
Lola Stamm |
Spirochetal motility and chemotaxis genes |
Thursday Morning, January 22
(9:00-12:30)
Antigens and Host Responses
Discussion Leader--Janis Weis
Michael Norgard |
Structure-function relationships for T. pallidum lipoproteins |
Linda Bockenstedt |
Role of specific immunity in murine Lyme borreliosis |
Reinhard Straubinger |
Immune and cytokine response to Borrelia burgdorferi during acute Lyme arthritis in the dog model |
Barbara Johnson |
Characterization of the cartilage proteoglycan (aggrecan) binding activity of Borrelia burgdorferi |
Bettina Wilske |
Antigenic heterogeneity in B. burgdorferi strains from Europe |
Markus Simon |
Strategies for Lyme disease vaccination |
Thursday Evening, January
22 (7:30-9:30) Discussion Leader--Sheila Lukehart
Business meeting |
Overview |
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