| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | REGENERATION: LESSONS FROM DEVELOPMENTAL BIOLOGY |
| Discussion Leader: Joyce Wong (Boston University) |
| 7:40 pm - 8:20 pm | Elly Tanaka (Center for Regenerative Therapies Dresden, Germany)
"The remarkable phenomenon of salamander limb regeneration: How do they do it?" |
| 8:20 pm - 8:35 pm | Discussion |
| 8:35 pm - 9:15 pm | Brant Weinstein (National Institutes of Health)
"A fishes eye view of angiogenesis" |
| 9:15 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | ENGINEERED STEM CELL ENVIRONMENTS: THE PATH TO THERAPEUTICS |
| Discussion Leader: Arthur Martin (Corning, Inc.) |
| 9:00 am - 9:10 am | Session Leader's Introduction |
| 9:10 am - 9:30 am | Joerg Lahann (Univ of Michigan)
"Synthetic Polymer Coatings for expansion of Pluripotent Stem Cells" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:05 am | Kristi Anseth (Univ of Colorado)
"Dynamically tunable hydrogels: Stem cell biology in 4 dimensions" |
| 10:05 am - 10:20 am | Discussion |
| 10:20 am - 10:45 am | Coffee Break |
| 10:45 am - 11:05 am | David Schaffer (UC Berkeley)
"Engineering Biomaterials to Investigate Structure-Function Relationships in the Stem Cell Niche" |
| 11:05 am - 11:20 am | Discussion |
| 11:20 am - 11:40 am | Steve Oh (Bioprocessing Technology Institute, Singapore)
"Translating stem cells to 3D microcarrier bioprocesses - achievements and challenges" |
| 11:40 am - 11:55 am | Discussion |
| 11:55 am - 12:15 pm | Karl Tryggvason (Karolinska Institute, Sweden)
"Expansion of pluripotent hES cells from single cell suspensions on laminin matrices" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | INTEGRATED COMPUTATION AND EXPERIMENT: FROM MOLECULES TO CELLS TO SYSTEMS |
| Discussion Leader: Deborah Leckband (Univ Illinois-Urbana Champaign) |
| 7:30 pm - 7:40 pm | Session Leader's Introduction |
| 7:40 pm - 8:00 pm | Igal Szleifer (Northwestern University)
"What is the pH in a biomaterial? Lessons from gels and other systems" |
| 8:00 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:35 pm | Celeste Nelson (Princeton University)
"Multicellular dynamics in engineered tissues" |
| 8:35 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:10 pm | Todd McDevitt (Georgia Tech/Emory University)
"Engineering stem cell extracellular environments to direct emergent behaviors" |
| 9:10 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | VASCULARIZATION, INNERVATION, AND TISSUE INTEGRATION |
| Discussion Leader: Shelly Sakiyama-Elbert (Washington University) |
| 9:00 am - 9:10 am | Session Leader's Introduction |
| 9:10 am - 9:30 am | Andrew Putnam (Univ of Michigan)
"Neovascularization and the Matrix: It's Complicated." |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:05 am | Edward Botchwey (University of Virginia)
"Tissue engineering by in situ manipulation of endogenous stem and progenitor cells" |
| 10:05 am - 10:20 am | Discussion |
| 10:20 am - 10:45 am | Coffee Break |
| 10:45 am - 11:05 am | Laura Suggs (University of Texas at Austin)
"Biomaterial Approaches to Stem Cell Therapy" |
| 11:05 am - 11:20 am | Discussion |
| 11:20 am - 11:40 am | Erin Lavik (Case Western Reserve University)
"Engineering blood vessels to promote neurite outgrowth" |
| 11:40 am - 11:55 am | Discussion |
| 11:55 am - 12:15 pm | Anthony Windebank (Mayo Clinic)
"Taking three dimensional Scaffolds for Nervous System Repair into the Clinic" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TRANSLATING BASIC SCIENCE DISCOVERIES TO THE CLINIC |
| Discussion Leader: David Grainger (University of Utah) |
| 7:30 pm - 7:40 pm | Session Leader's Introduction |
| 7:40 pm - 8:00 pm | Elliott Chaikof (Beth Israel Deaconess Medical Center, Boston MA)
"A Bottom-Up Approach to Engineering Fiber-Reinforced Tissue Composites" |
| 8:00 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:35 pm | Masayuki Yamato (Tokyo Women's Medical University, Tokyo Japan)
"Cell sheet engineering for regenerative medicine: current status of its clinical translation" |
| 8:35 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:10 pm | Molly Stevens (Imperial College, London England)
"Translating technologies for musculoskeletal repair" |
| 9:10 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ADVANCES IN NANOTECHNOLOGY AND MATERIALS SCIENCE FOR BIOMEDICINE |
| Discussion Leader: Marcus Textor (ETH-Zurich, Switzerland) |
| 9:00 am - 9:10 am | Session Leader's Introduction |
| 9:10 am - 9:30 am | Peter Fratzl (Max Planck Institute, Golm Germany)
"Materials science of bone regeneration" |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:05 am | Michael Smith (Boston University)
"Multi-scale mechanics of biological materials: from matrix molecules to cells" |
| 10:05 am - 10:20 am | Discussion |
| 10:20 am - 10:45 am | Coffee Break |
| 10:45 am - 11:05 am | Paula Hammond (MIT)
"Nanolayer Assemblies for Controlled Delivery from 2D and 3D Surfaces" |
| 11:05 am - 11:20 am | Discussion |
| 11:20 am - 11:40 am | Prashant Kumta (Univ of Pittsburgh)
"Experimental and Theoretical Studies on Degradable Metals and Ceramics" |
| 11:40 am - 11:55 am | Discussion |
| 11:55 am - 12:15 pm | Francesco Stellacci (EPFL, Lausanne Switzerland)
"Cell Membrane Penetrating Nanoparticles: From Fundamental Science to Application" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MACROPHAGE: FOREIGN BODY RESPONSE, DIVERSITY AND REPAIR |
| Discussion Leader: Julia Babensee (Georgia Tech) |
| 7:30 pm - 7:40 pm | Session Leader's Introduction |
| 7:40 pm - 8:00 pm | Michael Sefton (University of Toronto, Canada)
"Regeneration inducing biomaterials: alternative foreign body responses" |
| 8:00 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:35 pm | S. Joseph Leibovich (New Jersey Medical School)
"Macrophage Plasticity - Phenotypic Regulation via Adenosine Receptors" |
| 8:35 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:10 pm | Sabine Eming (University of Cologne, Germany)
"Differential roles of macrophages in diverse phases of skin repair" |
| 9:10 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 9:00 am - 12:30 pm | ENGINEERING NEURAL INTERFACES |
| Discussion Leader: Ravi Bellamkonda (Georgia Tech) |
| 9:00 am - 9:10 am | Session Leader's Introduction |
| 9:10 am - 9:30 am | Patrick Tresco (University of Utah)
"The challenge of integrating chronic recording electrodes into brain tissue." |
| 9:30 am - 9:45 am | Discussion |
| 9:45 am - 10:05 am | Mario Romero-Ortega (UT-Southwestern)
"Specific Sensory and Motor Recordings Through Peripheral Nerve Regenerative Multielectrode Interfaces" |
| 10:05 am - 10:20 am | Discussion |
| 10:20 am - 10:45 am | Coffee Break |
| 10:45 am - 11:05 am | Stephanie Lacour (EPFL Lausanne, SWITZERLAND)
"Strategies to improve the mechanical compatibility between neural electrodes and neural tissues" |
| 11:05 am - 11:20 am | Discussion |
| 11:20 am - 11:40 am | Justin Williams (University of Wisconsin)
"In Situ Interrogation of Brain Tissue-Implant Interfaces" |
| 11:40 am - 11:55 am | Discussion |
| 11:55 am - 12:15 pm | Tracy Cui (University of Pittsburgh)
"Bioengineering Approach Targeting Neuronal Loss and Glial Scar Around Neural Probes" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | LESSONS FROM TRANSLATIONAL RESEARCH |
| Discussion Leader: Art Coury (Genzyme, Inc., retired) |
| 7:30 pm - 8:30 pm | Robert S. Langer (MIT)
"The Path to Translation: Lessons Learned Along the Way" |
| 8:30 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
