SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 7:45 pm | Introductory Comments by Alexei Tepikin and Kevin Foskett |
7:45 pm - 9:30 pm | CALCIUM SIGNALLING IN BIOENERGETICS AND APOPTOSIS |
7:45 pm - 8:15 pm | Discussion Leader: Tullio Pozzan (University of Padua)
"State of the field (review/introductory lecture)" |
8:15 pm - 8:40 pm | Rosario Rizzuto (University of Ferrara)
"Mitochondrial calcium channels in apoptosis and autophagy" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Michael Duchen (University College London)
"Modulation of mitochondrial pathways of apoptosis by the ATPase inhibitory protein, IF1" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CALCIUM SIGNALLING IN DISEASE AND AGING |
9:00 am - 9:05 am | Discussion Leader: Ernesto Carafoli (University of Padua) "Introduction" |
9:05 am - 9:30 am | Stephen Pandol (UCLA School of Medicine)
"Calcium, a co-conspirator in pancreatitis?" |
9:30 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Hiroko Bannai (RIKEN, Japan)
"Calcium-dependent tuning of inhibitory neurotransmission based on GABAAR diffusion dynamics" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break / Group Photo |
10:30 am - 10:55 am | Natalia Prevarskaya (University of Lille)
"Calcium and cancer hallmarks" |
10:55 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Grace E. Stutzmann (Rosalind Franklin University)
"Deviant neuronal calcium signalling and early synaptic deficits in Alzheimer's disease" |
11:35 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Llewelyn Roderick (The Babraham Institute)
"Calcium signaling and cardiac hypertrophy" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session 1 |
5:30 pm - 7:30 pm | CALCIUM STORES AND CALCIUM RELEASE CHANNELS |
5:30 pm - 5:35 pm | Discussion Leader: Aldebaran Hofer (Harvard Medical School) "Introduction" |
5:35 pm - 6:00 pm | Antony Galione (Oxford University)
"NAADP receptors and their role in calcium signaling" |
6:00 pm - 6:15 pm | Discussion |
6:15 pm - 6:40 pm | Barbara Ehrlich (Yale University)
"Regulation of intracellular calcium release by calcium binding proteins" |
6:40 pm - 6:55 pm | Discussion |
6:55 pm - 7:20 pm | Colin Taylor (Cambridge University)
"Tuning the sensitivity of IP3 receptors" |
7:20 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MECHANISMS OF CA2+ ENTRY |
9:00 am - 9:05 am | Discussion Leader: Anjana Rao (Harvard Medical School) "Introduction" |
9:05 am - 9:30 am | Anant Parekh (Oxford University)
"Mechanisms regulating STIM1 movement and ICRAC activation" |
9:30 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Late Breaking Science Talk: Trevor Shuttleworth (University of Rochester)
"Orai subunit ARChitecture of ARC channels" |
9:55 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Indu Ambudkar (National Institute of Health/NIDCR)
"Lipid rafts domains and regulation of store-operated calcium entry" |
10:55 am - 11:10 am | Discussion |
11:10 am - 11:35 am | Richard Lewis (Stanford University School of Medicine)
"A molecular mechanism for CRAC channel activation" |
11:35 am - 11:50 am | Discussion |
11:50 am - 12:10 pm | Late Breaking Science Talk: Patrick Hogan (Harvard Medical School)
"STIM1, Orai1, and store-operated calcium entry" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session 1 |
5:30 pm - 7:30 pm | CHANNELS INVOLVED IN CA2+ ENTRY |
5:30 pm - 5:35 pm | Discussion Leader: Kevin Foskett (University of Pennsylvania) "Introduction" |
5:35 pm - 5:55 pm | Late Breaking Science Talk: Don Gill (Temple University School of Medicine) |
5:55 pm - 6:05 pm | Discussion |
6:05 pm - 6:15 pm | Ivan Bogeski (Saarland University, Germany)
"Redox regulation of Orai channels: a mechanism to tune T-cell responses" |
6:15 pm - 6:20 pm | Discussion |
6:20 pm - 6:30 pm | Roger J. Thompson (Hotchkiss Brain Institute, Calgary, Canada)
"Pannexin-1 Channels and Neuronal Calcium Deregulation" |
6:30 pm - 6:35 pm | Discussion |
6:35 pm - 7:30 pm | Debate: "Are TRP channels involved in store-operated Ca2+ entry?" |
| Shmuel Muallem (University of Texas, Southwestern Medical Centre) vs. Jim Putney (National Institute of Environmental Health Science) |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | INTERACTING SECOND MESSENGER CASCADES |
9:00 am - 9:05 am | Discussion Leader: Indu Ambudkar (National Institute of Health/NIDCR) "Introduction" |
9:05 am - 9:30 am | Aldebaran Hofer (Harvard Medical School)
"Store-operated second messenger signaling: variations on a theme" |
9:30 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Dermot Cooper (Cambridge, UK)
"Exploring Calcium and cAMP dynamics in a Calcium-sensitive adenylyl cyclase microdomain" |
9:55 am - 10.00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | David Yule (University of Rochester)
"InsP3 receptors; subtype specific regulation of Ca2+ release by ATP" |
10:55 am - 11:10 am | Discussion |
11:10 am - 11:30 am | Late Breaking Science Talk: Gyorgy Hajnoczky (Thomas Jefferson University) |
11:30 am - 11:40 am | Discussion |
11:40 am - 12:00 pm | Late Breaking Science Talk: Sandip Patel (University College London)
“Essential requirement for two pore channel 1 in NAADP-mediated calcium signalling” |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session 2 |
5:30 pm - 7:30 pm | COMPARATIVE PHYSIOLOGY OF CALCIUM SIGNALS |
5:30 pm - 5:35 pm | Discussion Leader: Mike Berridge (The Babraham Institute) "Introduction" |
5:35 pm - 6:00 pm | Alex Webb (University of Cambridge)
"Circadian Regulation of Calcium Signaling in Arabidopsis" |
6:00 pm - 6:15 pm | Discussion |
6:15 pm - 6:40 pm | Luigia Santella (Stazione Zoologica Anton Dohrn)
"Actin cytoskeleton modulates calcium signaling in starfish oocytes" |
6:40 pm - 6.55 pm | Discussion |
6:55 pm - 7:05 pm | Gaiti Hasan (TIFR, Bangalore, India)
"Intracellular Ca2+ release and Store-operated Ca2+ entry are required for Drosophila flight" |
7:05 pm - 7:10 pm | Discussion |
7:10 pm - 7:20 pm | Myriam Charpentier (Norwich, UK)
"Arbuscular mycorrhiza and Nod factor induced nuclear-localized calcium oscillations: identifying the calcium channel" |
7:20 pm - 7:25 pm | Discussion |
7:25 pm - 7:30 pm | General Discussion |
7:30 pm - 8:00 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
8:00 pm | Dinner |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | DOWNSTREAM FROM CA2+ SIGNALING - THE PHILOSOPHY OF CALCIUM SENSORS |
9:00 am - 9:05 am | Discussion Leader: Robert Burgoyne (The University of Liverpool) "Introduction" |
9:05 am - 9:30 am | Mitsu Ikura (University of Toronto)
"Structural insights into STIM1-mediated initiation of store-operated calcium entry" |
9:30 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Talk Selected From Posters (TBA) |
9:55 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Annete Draeger (University of Bern)
"Dynamic regulation of ceramide platforms by intracellular calcium" |
10:55 am - 11:10 am | Discussion |
11:10 am - 11:35 am | David Yue (The John Hopkins University School of Medicine)
"Novel mechanisms underlying smart Ca2+ decoding by the CaM/Ca channel complex" |
11:35 am - 11:50 am | Discussion |
11:50 am - 12:10 pm | Late Breaking Science Talk: Ilya Bezprozvanny (UT Southwestern medical centre at Dallas)
"Presenilins and calcium signaling in mouse models of AD" |
12:10 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session 2 |
5:30 pm - 7:30 pm | KEYNOTE LECTURE AND FINAL DISCUSSION |
5:30 pm - 5:40 pm | Discussion Leader: Ole Petersen (The University of Liverpool) "Introduction" |
5:40 pm - 6:40 pm | Tobias Mayer (Stanford University)
"Ca2+ signaling from the endoplasmic reticulum to the plasma membrane" |
6:40 pm - 7:00 pm | Discussion |
7:00 pm - 7:30 pm | General Discussion (any topic of the conference) |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |