Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: The Road to Discovery of MCU
Discussion Leader: Galina Schmunk (University of California, Irvine, USA)
3:15 pm - 3:50 pm
Rosario Rizzuto (University of Padova, Italy)
"The Road to Discovery of MCU"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Role of Ca2+ Signaling in Disease and Therapy
Discussion Leaders: Andrew Thomas (Rutgers University, USA) and Crystal Archer (University of Texas Health Science Center at San Antonio, USA)
5:30 pm - 5:45 pm
Daniela Arduino (Gene Center Munich, Germany)
"An Orthogonal Yeast-Mammalian Chemical Screen Identifies DA2801 as a Novel Inhibitor of the Mitochondrial Ca2+ Uniporter"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Miryam Hortua Triana (Center for Tropical and Emerging Global Diseases, University of Georgia, USA)
"Two Mechanisms of Ca2+ Entry in Toxoplasma gondii , Each with Specific Roles in Virulence Pathways"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Pawel Ferdek (Cardiff University, United Kingdom)
"BH3 Mimetic-Elicited Ca2+ Signals in Pancreatic Acinar Cells Are Dependent on Bax and Can Be Reduced by Ca2+ -Like Peptides"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Iman Azimi (The University of Queensland, Australia)
"TRPC1 Regulates Hypoxia Associated Events in PTEN-Deficient Breast Cancer Cells"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Pishyaporn Sritangos (University of Manchester, United Kingdom)
"The Role of PMCA4 in Pancreatic Cancer"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Ketaki Mhatre (Charité Campus Virchow-Klinikum, Germany)
"Crosstalk Between FGF23 and Angiotensin II Mediated Ca2+ -Dependent Signaling in Cardiac Hypertrophy"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Fine-Tuning Ca2+ Signaling: Channels, Transporters, and Ca2+ -Binding Proteins / Mentorship Component: Navigating Conference Networking
Discussion Leaders: Gary St. John Bird (National Institute of Environmental Health Sciences, NIH, USA) and Radhika Khandelwal (Centre for Cellular and Molecular Biology, India)
9:00 am - 9:15 am
Rahul Banerjee (Johns Hopkins University School of Medicine, USA)
"Bilobal Architecture of Calmodulin in L-Type Ca2+ Channel Regulation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Christina Go (Lewis Katz School of Medicine, Temple University, USA)
"Competitive POST/STIM1-Dependent Mechanisms Controlling PMCA4 Function During T Cell Activation"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Ehsan Kheradpezhouh (Australian National University, Australia)
"TRPA1 Expression and Its Functional Activation in Rodent Cortex"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Crystal Archer (University of Texas Health Science Center at San Antonio, USA)
"A Possible Structural Mechanism of Phosphorylation in Mediating Crosstalk Between Calmodulin and PIP2 on KCNQ4 K+ Ion Channels"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Julia Gerasimenko (School of Biosciences, Cardiff University, United Kingdom)
"Successful Conference Networking and Academic Career Development"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Advances in Store-Operated Ca2+ Entry
Discussion Leaders: Aparna Gudlur (La Jolla Institute for Allergy and Immunology, USA) and Emma McIvor (University of Nottingham, United Kingdom)
1:30 pm - 1:45 pm
Priscilla Yeung (Northwestern University, USA)
"Interactions Between Transmembrane Helices in ORAI1 Regulate STIM1-Mediated Activation"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Niroj Shrestha (Medical University of Graz, Austria)
"TRIC Channels Govern Frequency of Oscillatory Ca2+ Signals by Interference with STIM-Orai Ca2+ Entry Machinery"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Monica Bulla Didier (University of Geneva, Switzerland)
"ORAI1 Mutations with Distinct Channel Gating Defects Linked to Tubular Aggregate Myopathy"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
