Intracellular Calcium Signalling in Normal Physiology and Disease

June 17 - 18, 2017

Chairs

and

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Calcium Signalling is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas. The aim of this Gordon Research Seminar is to bring together students, postdocs and junior investigators in the field of calcium signaling to share cutting-edge research and to create opportunities for future collaborations.

Topics of discussion in scientific sessions include structure and function of calcium signaling molecules and components, and advances in understanding calcium signaling and the associated changes in physiology and disease. The focus of this meeting is to provide young scientists with an inviting forum for the exchange and discussion of primarily new/unpublished data on intracellular calcium signaling.

Related Meeting

This GRS will be held in conjunction with the "Calcium Signalling" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:30 pm - 4:30 pm	Arrival and Check-in
3:00 pm - 3:15 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm	Keynote Session: The Road to Discovery of MCU Discussion Leader:
3:15 pm - 3:50 pm	"The Road to Discovery of MCU"
3:50 pm - 4:00 pm	Discussion
4:00 pm - 5:30 pm	Poster Session
5:30 pm - 7:30 pm	Role of Ca²⁺ Signaling in Disease and Therapy Discussion Leaders: and
5:30 pm - 5:45 pm	"An Orthogonal Yeast-Mammalian Chemical Screen Identifies DA2801 as a Novel Inhibitor of the Mitochondrial Ca²⁺ Uniporter"
5:45 pm - 5:50 pm	Discussion
5:50 pm - 6:05 pm	"Two Mechanisms of Ca²⁺ Entry in Toxoplasma gondii, Each with Specific Roles in Virulence Pathways"
6:05 pm - 6:10 pm	Discussion
6:10 pm - 6:25 pm	"BH3 Mimetic-Elicited Ca²⁺ Signals in Pancreatic Acinar Cells Are Dependent on Bax and Can Be Reduced by Ca²⁺-Like Peptides"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:45 pm	"TRPC1 Regulates Hypoxia Associated Events in PTEN-Deficient Breast Cancer Cells"
6:45 pm - 6:50 pm	Discussion
6:50 pm - 7:05 pm	"The Role of PMCA4 in Pancreatic Cancer"
7:05 pm - 7:10 pm	Discussion
7:10 pm - 7:25 pm	"Crosstalk Between FGF23 and Angiotensin II Mediated Ca²⁺-Dependent Signaling in Cardiac Hypertrophy"
7:25 pm - 7:30 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Fine-Tuning Ca²⁺ Signaling: Channels, Transporters, and Ca²⁺-Binding Proteins / Mentorship Component: Navigating Conference Networking Discussion Leaders: and
9:00 am - 9:15 am	"Bilobal Architecture of Calmodulin in L-Type Ca²⁺ Channel Regulation"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Competitive POST/STIM1-Dependent Mechanisms Controlling PMCA4 Function During T Cell Activation"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"TRPA1 Expression and Its Functional Activation in Rodent Cortex"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"A Possible Structural Mechanism of Phosphorylation in Mediating Crosstalk Between Calmodulin and PIP₂ on KCNQ4 K⁺ Ion Channels"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	"Successful Conference Networking and Academic Career Development"
10:50 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Advances in Store-Operated Ca²⁺ Entry Discussion Leaders: and
1:30 pm - 1:45 pm	"Interactions Between Transmembrane Helices in ORAI1 Regulate STIM1-Mediated Activation"
1:45 pm - 1:50 pm	Discussion
1:50 pm - 2:05 pm	"TRIC Channels Govern Frequency of Oscillatory Ca²⁺ Signals by Interference with STIM-Orai Ca²⁺ Entry Machinery"
2:05 pm - 2:10 pm	Discussion
2:10 pm - 2:25 pm	"ORAI1 Mutations with Distinct Channel Gating Defects Linked to Tubular Aggregate Myopathy"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes