Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: RNA Delivery and Therapeutics
Discussion Leader: Alexander Kabanov (University of North Carolina at Chapel Hill, USA)
7:40 pm - 8:20 pm
Chad Mirkin (Northwestern University, USA)
"Spherical Nucleic Acids for Cancer Immunotherapy and Gene Regulation"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
Daniel Anderson (Massachusetts Institute of Technology, USA)
"Nano-Delivery of Nucleic Acids and Genome Editing Tools"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Attacking Tumor Microenvironment
Discussion Leader: Maria Vicent (Centro de Investigacion Principe Felipe, Spain)
9:00 am - 9:40 am
Leaf Huang (University of North Carolina at Chapel Hill, USA)
"Targeting Tumor Associated Fibroblasts for Therapy"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
Sangeeta Bhatia (Massachusetts Institute of Technology, USA)
"Activity-Based Nano Sensors of the Tumor Microenvironment"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
Maria Jose Alonso (University of Santiago de Compostela, Spain)
"Multifunctional Nanocapsules for Chimio- and Immunotherapy"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Early Diagnosis, Imaging and Treatment
Discussion Leader: Shawn Chen (National Institute of Biomedical Imaging and Bioengineering, NIH, USA)
7:30 pm - 8:10 pm
Rachela Popovtzer (Bar-Ilan University, Israel)
"Nanoparticles for In-Vivo Cell Tracking: Imaging, Detection and Stratified Medicine"
8:10 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Shan Wang (Stanford University, USA)
"Nanotechnology for Probing Cancer Pathways, Detecting Cancer Early, and Treating Cancer More Effectively"
9:10 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Cancer Vaccines and Immunoengineering
Discussion Leader: Darrell Irvine (Massachusetts Institute of Technology, USA)
9:00 am - 9:40 am
Liangfang Zhang (University of California, San Diego, USA)
"Biomimetic Nanoparticles for Anticancer Vaccination"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
Michael Goldberg (Dana-Farber Cancer Institute, USA)
"Leveraging Nanotechnology to Improve Cancer Immunotherapy"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
Melody Swartz (University of Chicago, USA)
"Nanomaterials Targeting Lymphatic Vessels for Cancer Immunotherapy"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Natural Nanomaterials
and Cell-Based Therapies
Discussion Leader: Leaf Huang (University of North Carolina at Chapel Hill, USA)
7:30 pm - 8:10 pm
Ennio Tasciotti (Houston Methodist Hospital, USA)
"Biomimetic Engineering of Materials to Tune Immune Response and Inflammation"
8:10 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Molly Shoichet (University of Toronto, Canada)
"Hyaluronan-Based Hydrogels Enable 3D Cell Culture and Biomimetic Drug Screening"
9:10 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Targeted, Responsive
and Remotely Controlled Nanomedicines
Discussion Leader: Tatiana Bronich (University of Nebraska Medical Center, USA)
9:00 am - 9:40 am
Kazunori Kataoka (iCONM - Kawasaki Institute of Industrial Promotion, Japan)
"New Paradigm in Nanosystems Penetration into Cancer Crossing Vascular and Stromal Barriers"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
Omid Farokhzad (Brigham and Women's Hospital / Harvard University, USA)
"Targeted Polymeric Nanoparticles: From Discovery to Clinical Trials and Lessons Learned"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
Alberto Gabizon (Shaare Zedek Medical Center / Hebrew University of Jerusalem, Israel)
"Strategies for Development of Liposome-Based Nanomedicines - From Bench to Bedside"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Nanoinformatics, Rational Design, Modeling and Simulation
Discussion Leader: Alexander Tropsha (University of North Carolina at Chapel Hill, USA)
7:30 pm - 8:10 pm
Fred Prior (University of Arkansas for Medical Sciences, USA)
"Informatics to Enhance Rigor and Transparency in Nanomedicine Research"
8:10 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Stephanie Morris (National Cancer Institute, NIH, USA) and Chiara Pastore (Nature Nanotechnology, United Kingdom)
"Informatics and Data Management in Nanomedicine"
9:10 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Pre-Clinical and Clinical Experience and Lessons Learned
Discussion Leaders: Rogerio Gaspar (University of Lisbon, Portugal) and Puja Sapra (Pfizer, USA)
9:00 am - 9:40 am
Kazuhiro Takahashi (NanoCarrier Co., Ltd., Japan)
"Clinical Development Strategy of Micellar Nanoparticles in NanoCarrier"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
Michelle Bradbury (Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, USA)
"Image-Directed Surgical Treatment of Cancer Using Ultrasmall Silica Nanoparticles: Design, Evaluation and Translation from Lab to Clinic"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
Lawrence Mayer (Jazz Pharmaceuticals, Canada)
"Paving a Novel Approach to Developing Anticancer Combinations Through Tumor-Targeting
Nanomedicines"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Selected Poster Presentations
8 posters will be selected by the GRC vice chair for 10 minute oral presentations, followed by 5 minutes of discussion.
Discussion Leader: Ronit Satchi-Fainaro (Sackler Faculty of Medicine, Tel Aviv University, Israel)
7:30 pm - 7:40 pm
Daniel Heller (Memorial Sloan Kettering Cancer Center, USA)
"Targeted Delivery to Tumor Vasculature Modulates Kinase Inhibitor Pharmacodynamics"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Elena Batrakova (University of North Carolina at Chapel Hill, USA)
"Engineering Exosomes for Targeted Paclitaxel Delivery to Pulmonary Metastases: In Vitro and In Vivo Evaluations"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Assaf Zinger (Technion - Israel Institute of Technology, Israel)
"Pancreatic Ductal Adenocarcinoma Nano-Diggers"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Ayelet David (Ben-Gurion University of the Negev, Israel)
"E-Selectin-Targeted Copolymer Attenuates the Development and Progression of both Atherosclerosis and Cancer"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Helena Florindo (Universidade de Lisboa, Portugal)
"Insights on the Impact of Controlled Multicomponent Nanoscale Systems on Immune Modulation Against Solid Tumors"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Brynn Olden (University of Washington, USA)
"Cationic Polymers for Non-Viral Gene Delivery to Primary Human T Cells"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
William Payne (University of Nebraska Medical Center, USA)
"Computational Modeling of Polymeric Nanoparticles for Rational Design in Drug Delivery"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Abdullah Syed (University of Toronto, Canada)
"3D Mapping of Nanoparticles in Tumours"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure