Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
New Horizons for Cancer Nanotechnology
Discussion Leader: Shiran Ferber (Brigham and Women's Hospital, Harvard Medical School / IMES, Massachusetts Institute of Technology, USA)
3:45 pm - 4:20 pm
Dennis Discher (University of Pennsylvania, USA)
"Where Are We Going and Where Have I Been: From Genomics and Immunotherapy Back to Polymers and Biophysics"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Beyond EPR: New Ideas for Cancer Nanomedicine
Discussion Leader: Abdullah Syed (University of Toronto, Canada)
7:30 pm - 7:50 pm
Hanan Abumanhal (Technion - Israel Institute of Technology, Israel)
"Modulating the pH: Liposomal Bicarbonate Enhance Doxorubicin Activity in Breast Cancer"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Mengying Hu (University of North Carolina at Chapel Hill, USA)
"Fetching an Endogenous Fibrosis Resolution Mechanism: Gene Therapy for Liver Metastasis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Rashmi Mohanty (University of Texas at Austin, USA)
"Peptide Coatings to Improve Nanoparticle Diffusivity in Tumor Extracellular Matrix"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Shrey Sindhwani (University of Toronto, Canada)
"How Do Nanoparticles Enter Solid Tumours?"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Boosting Cancer Immunotherapy with Nanotechnology
Discussion Leader: Zvi Yaari (Memorial Sloan Kettering Cancer Center, USA)
9:00 am - 9:20 am
Xiao Huang (University of California, San Francisco, USA)
"DNA-Scaffolded Biomaterials Enable Modular and Tunable Control of Cell-Based Cancer Immunotherapies"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Lior Levy (Technion - Israel Institute of Technology, Israel)
"iNano-Ghosts: A Cell-Free Nanometric System for Off-the-Shelf Cancer Immunotherapy"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Kaiyuan Ni (University of Chicago, USA)
"Nanoscale Metal-Organic Frameworks Potentiate Checkpoint Blockade Immunotherapy upon Low-Dose X-Ray Irradiation"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Jorieke Weiden (Radboud Institute for Molecular Life Sciences, The Netherlands)
"Polyisocyanopeptide Polymers as Versatile Tools for Efficient T Cell Expansion and Delivery"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers in Cancer Nanotechnology
Established investigators will speak on future directions in cancer nanotechnology, transitioning to independence, publishing strategies, and how to advance in academia and industry.
Discussion Leaders: Chintan Kapadia (University of Delaware, USA) and Mijin Kim (Memorial Sloan Kettering Cancer Center, USA)
1:30 pm - 2:30 pm
Panel Discussion
Creating Your Path: Advice for Early Career Scientists
Ennio Tasciotti (Houston Methodist Research Institute, USA)
Ronit Satchi-Fainaro (Tel Aviv University, Israel)
Darrell Irvine (Massachusetts Institute of Technology, USA)
Dennis Discher (University of Pennsylvania, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
