Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Cannabidiol (CBD): What, Where and How
Discussion Leader: Ozge Gunduz-Cinar (National Institute on Alcohol Abuse and Alcoholism, NIH, USA)
3:15 pm - 3:30 pm
Simon Chamberland (New York University, USA)
"Cannabidiol Elevates the Ratio of Feedforward:Feedback Inhibition to Dampen Hippocampal Activity Propagation"
3:30 pm - 3:35 pm
Discussion
3:35 pm - 3:55 pm
Somayeh Mirlohi (Macquarie University, Australia)
"Modulation of T-Type Calcium Channels by Phytocannabinoids"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Entourage: Terpenes, Flavonoids and Interactions Between Phyto- and Endocannabinoids
Discussion Leader: Gyula Balla (Institute of Experimental Medicine, Hungarian Academy of Sciences, Hungary)
5:30 pm - 5:45 pm
Melissa Benson (The University of Sydney, Australia)
"THCA Has Varying Anticonvulsant Efficacy Across a Range of Mouse Seizure Models"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Tallan Black (College of Pharmacy and Nutrition, University of Saskatchewan, Canada)
"In Vivo Structure-Function Behavioral Analysis of GAT211 Analogs"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Zsofia Laszlo (Institute of Experimental Medicine, Hungarian Academy of Sciences, Hungary)
"Alpha/Beta Hydrolase 4 (Abhd4) Controls Cellular Survival in the Germinative Zones of Developing Mouse Brain"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Jakub Mlost (Institute of Pharmacology, Polish Academy of Sciences, Poland)
"Analgesic Effects and No Tolerance with Prolonged β-Caryophyllene Treatment in the Animal Model of Osteoarthritis: CB2 and Opioid Receptor Dependent Mechanism of Action"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Catharine Mielnik (University of Toronto, Canada)
"Dose, Ratio, Age and Sex Effects of Combinations of THC and CBD in Models of Psychosis"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Cristina Miralpeix (Universitat Internacional de Catalunya (UIC), Spain)
"CPT1C: A Novel Regulator of ABHD6 Activity"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Cannabinoids in the Treatment and Etiology of Disease
Discussion Leader: Debra Karhson (Stanford University, USA)
9:00 am - 9:15 am
Leah Mayo (Center for Social and Affective Neuroscience, Linköping University, Sweden)
"Beneficial Effects of Pharmacological Inhibition of Fatty Acid Amide Hydrolase (FAAH) on Fear- and Stress-Related Behaviors in Healthy Humans"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Jayme McReynolds (University of Cincinnati College of Medicine, USA)
"Involvement of Mesolimbic Endocannabinoid Signaling in Stress-Induced Escalation of Cocaine Intake in Rats"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Michaela Dvorakova (Institute of Molecular Genetics of the ASCR, v.v.i., Czech Republic)
" Distorted Endocannabinoid Signaling in SGIP1 Knock-out Mice Correlates with Altered Modulation of Anxiety, Fear, Stress and Pain Processing"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Jack Jacobs (University of Pennsylvania, USA)
"Endocannabinoid Metabolites Protect Against Seizures in Drosophila melanogaster by Reducing Levels of the TRP Channel Water Witch"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Lyndsey Anderson (Lambert Initiative for Cannabinoid Therapeutics, University of Sydney, Australia)
"A Preclinical Study Exploring Pharmacodynamic and Pharmacokinetic Interactions Between Clobazam and Cannabidiol in a Mouse Model of Dravet Syndrome"
10:35 am - 10:40 am
Discussion
10:40 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers in Cannabinoids: Academia, Pharmacy and Bench-to-Bedside Research
Discussion Leader: Andrew Scheyer (Institut de Neurobiologie de la Méditerranée (INMED), France)
1:30 pm - 2:30 pm
Panel Discussion
Careers in Cannabinoids: Academia, Pharmacy and Bench-to-Bedside Research
Jaideep Bains (University of Calgary, Canada)
Jacqueline Blankman (Lundbeck La Jolla Research Center Inc, USA)
Melanie Kelly (Dalhousie University, Canada)
Mario Stelt (Leiden University, The Netherlands)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes